Implantable drug delivery device and methods

    公开(公告)号:US10532132B2

    公开(公告)日:2020-01-14

    申请号:US13910730

    申请日:2013-06-05

    IPC分类号: A61L31/06 A61L31/16

    摘要: A method is provided for local controlled delivery of a drug to the seminal vesicle, the prostate, the ejaculatory duct, or the vas deferens of a patient in need of treatment. In one embodiment, the method includes implanting a resorbable drug delivery device within the seminal vesicle, the prostate, the ejaculatory duct, or the vas deferens of the patient. The drug delivery device may include an elastic device body housing at least one drug reservoir which contains at least one drug. In a preferred embodiment, the method further includes releasing the drug from the device in a controlled manner to, typically directly to, the seminal vesicle, the prostate, the ejaculatory duct, or the vas deferens.

    Implantable device with intravesical tolerability and methods of treatment
    6.
    发明授权
    Implantable device with intravesical tolerability and methods of treatment 有权
    具有膀胱内耐受性和治疗方法的植入式装置

    公开(公告)号:US08679094B2

    公开(公告)日:2014-03-25

    申请号:US12972364

    申请日:2010-12-17

    IPC分类号: A61K9/22

    摘要: Intravesical devices are provided that are wholly deployable within the bladder of a patient in need of treatment and are well tolerated by the patient. The device may include an elastic body having a retention shape having (i) dimensions that provide intravesical mobility and that prevent voiding of the medical device through the urethra, and (ii) dimensions, buoyancy, or both, that exclude the medical device from entering the orifices of the ureters. The elastic body may exert a maximum acting force less than 1 N when compressed to a shape with a maximum dimension in any dimension of 3 cm. The device may include a drug for controlled release within the bladder, for treatment of the bladder or a regional tissue. Methods of treatment are also provided that include selecting a patient in need of treatment in the bladder where tolerability of the treatment is a primary concern.

    摘要翻译: 提供了可以在需要治疗的患者的膀胱内完全展开并且被患者良好耐受的膀胱内装置。 该装置可以包括具有保持形状的弹性体,其具有(i)提供膀胱内移动性的尺寸并且防止医疗装置通过尿道的排尿,以及(ii)排除医疗装置进入的尺寸,浮力或两者 输尿管孔。 当压缩到任何尺寸为3cm的最大尺寸的形状时,弹性体可发挥小于1N的最大作用力。 该装置可以包括用于膀胱内控制释放的药物,用于膀胱或区域组织的治疗。 还提供了治疗方法,包括在膀胱中选择需要治疗的患者,其中治疗的耐受性是主要关注的。

    Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites
    10.
    发明申请
    Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites 审中-公开
    膀胱和其他泌尿生殖部位植入装置的系统和方法

    公开(公告)号:US20110218488A1

    公开(公告)日:2011-09-08

    申请号:US13042200

    申请日:2011-03-07

    IPC分类号: A61M31/00

    CPC分类号: A61M31/00

    摘要: An implantable drug delivery device includes a drug reservoir portion, a retention frame portion, and a guide wire portion. The drug reservoir portion houses a drug. The retention frame portion houses a retention frame. The guide wire portion defines a hollow bore for receiving a guide wire.

    摘要翻译: 可植入药物输送装置包括药物储存部分,保持框架部分和导丝部分。 药物储存部分容纳药物。 保持框架部分容纳保持框架。 引导线部分限定用于接收导丝的中空孔。