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1.发明申请Pharmaceutical Formulations and Compositions of a Selective Antagonist of Either CXCR2 or Both CXCR1 and CXCR2 and Methods of Using the Same for Treating Inflammatory Disorders 有权CXCR2或CXCR1和CXCR2两者的选择性拮抗剂的药物制剂和组合物及其用于治疗炎性疾病的方法公开(公告)号：US20080021100A1
公开(公告)日：2008-01-24
申请号：US11761588
申请日：2007-06-12
申请人： Jim Kou , Jonathan Eichman
发明人： Jim Kou , Jonathan Eichman
IPC分类号： A61K31/341 , A61P29/00
CPC分类号： A61K9/4825 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/4808 , A61K9/4858 , A61K9/4866 , A61K47/10 , A61K47/20 , A61K47/26 , A61K47/32 , A61K47/38
摘要： The present invention provides compositions as well as kits and methods based on a selective antagonist of either CXCR2 or both CXCR1 and CXCR2 that are useful for treating inflammatory disorders.
摘要翻译： 本发明提供了组合物以及基于可用于治疗炎症性疾病的CXCR2或CXCR1和CXCR2两者的选择性拮抗剂的试剂盒和方法。
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公开(公告)号：US20050037072A1
公开(公告)日：2005-02-17
申请号：US10946556
申请日：2004-09-21
申请人： S. Pather , Joseph Robinson , Jonathan Eichman , Rajendra Khankari , John Hontz
发明人： S. Pather , Joseph Robinson , Jonathan Eichman , Rajendra Khankari , John Hontz
IPC分类号： A61K9/00 , A61K9/20 , A61K9/28 , A61K9/46 , A61K31/4468 , A61K31/5415
CPC分类号： A61K9/0056 , A61K9/0007 , A61K9/006 , A61K9/2072 , A61K9/2866 , A61K9/2886 , A61K31/4468 , A61K31/5415
摘要： The pharmaceutical compositions of the present invention comprise rectally and vaginally administerable dosage forms that contain effervescent agents as penetration enhancers for drugs. Effervescence occurs in the rectum or vagina, once the dosage form is administered or at a predetermined time following administration. The effervescent agents can be used alone or in combination with pH adjusting substance, which further promote dissolution and absorption of the active ingredient.
摘要翻译： 本发明的药物组合物包含含有泡腾剂作为药物渗透促进剂的直肠和阴道给药剂型。 在直肠或阴道中发生泡腾，一旦施用剂型或在施用后的预定时间。 泡腾剂可以单独使用或与pH调节物质组合使用，这进一步促进活性成分的溶解和吸收。
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公开(公告)号：US20060292219A1
公开(公告)日：2006-12-28
申请号：US11511098
申请日：2006-08-28
CPC分类号： A61K9/0007 , A61K9/0056 , A61K9/006 , A61K31/4468 , A61K31/5415
摘要： A pharmaceutical dosage form adapted to supply a medicament to the oral cavity for buccal, sublingual or gingival absorption of the medicament which contains an orally administrable medicament in combination with an effervescent for use in promoting absorption of the medicament in the oral cavity. The use of an additional pH adjusting substance in combination with the effervescent for promoting the absorption drugs is also disclosed.
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公开(公告)号：US20050064030A1
公开(公告)日：2005-03-24
申请号：US10977029
申请日：2004-10-29
IPC分类号： A61K9/00 , A61K9/46 , A61K31/4468 , A61K31/5415 , A61K9/20 , B27N3/00
CPC分类号： A61K9/0007 , A61K9/0056 , A61K9/006 , A61K31/4468 , A61K31/5415
摘要： A pharmaceutical dosage form adapted to supply a medicament to the oral cavity for buccal, sublingual or gingival absorption of the medicament which contains an orally administrable medicament in combination with an effervescent for use in promoting absorption of the medicament in the oral cavity. The use of an additional pH adjusting substance in combination with the effervescent for promoting the absorption drugs is also disclosed.
摘要翻译： 一种药物剂型，其适于向口腔中提供药物的口腔，舌下或牙龈吸收，所述药物包含与可用于促进所述药物在口腔中的吸收的泡腾剂相结合的可口服给药的药物。 还公开了与泡腾剂结合使用另外的pH调节物质以促进吸收药物。
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