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公开(公告)号：US20120233855A1
公开(公告)日：2012-09-20
申请号：US13486864
申请日：2012-06-01
CPC分类号： A61N1/0556 , B29C39/10 , B29C45/14426 , Y10T29/49117
摘要： A nerve cuff comprising a wall band member having an inner surface defining a lumen when the wall band member is in a closed configuration for receiving a nerve therethrough. At least one longitudinal and contiguous conductor extends within the lumen. The conductor is insulated and has at least one exposed portion thereby providing an electrode. When mounting the nerve cuff to a nerve, each electrode is in electrical communication with the nerve. A multi-channel nerve cuff further comprises a plurality of longitudinal ridges formed on the inner surface with each adjacent pair of ridges defining a longitudinal chamber. Each chamber comprises a respective conductor extending therein. When mounting the multi-channel nerve cuff to the nerve, the ridges abut the nerve providing for each chamber to isolate respective longitudinal portions of the nerve. A method and an apparatus for manufacturing such nerve cuffs are also disclosed.
摘要翻译： 一种神经套囊，其包括壁带构件，当所述壁带构件处于用于接收神经的闭合构型时，所述壁带构件具有限定内腔的内表面。 至少一个纵向和相邻导体在管腔内延伸。 导体是绝缘的并且具有至少一个暴露部分，从而提供电极。 将神经袖带安装在神经上时，每个电极与神经电连通。 多通道神经套还包括形成在内表面上的多个纵向脊，每个相邻的脊脊限定纵向腔。 每个室包括在其中延伸的相应导体。 当将多通道神经袖带安装到神经时，脊邻接神经，提供每个腔室以分离神经的各个纵向部分。 还公开了用于制造这种神经箍的方法和装置。
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公开(公告)号：US08428749B2
公开(公告)日：2013-04-23
申请号：US13486864
申请日：2012-06-01
IPC分类号： A61N1/00
CPC分类号： A61N1/0556 , B29C39/10 , B29C45/14426 , Y10T29/49117
摘要： A nerve cuff comprising a wall band member having an inner surface defining a lumen when the wall band member is in a closed configuration for receiving a nerve therethrough. At least one longitudinal and contiguous conductor extends within the lumen. The conductor is insulated and has at least one exposed portion thereby providing an electrode. When mounting the nerve cuff to a nerve, each electrode is in electrical communication with the nerve. A multi-channel nerve cuff further comprises a plurality of longitudinal ridges formed on the inner surface with each adjacent pair of ridges defining a longitudinal chamber. Each chamber comprises a respective conductor extending therein. When mounting the multi-channel nerve cuff to the nerve, the ridges abut the nerve providing for each chamber to isolate respective longitudinal portions of the nerve. A method and an apparatus for manufacturing such nerve cuffs are also disclosed.
摘要翻译： 一种神经套囊，其包括壁带构件，当所述壁带构件处于用于接收神经的闭合构型时，所述壁带构件具有限定内腔的内表面。 至少一个纵向和相邻导体在管腔内延伸。 导体是绝缘的并且具有至少一个暴露部分，从而提供电极。 将神经袖带安装在神经上时，每个电极与神经电连通。 多通道神经套还包括形成在内表面上的多个纵向脊，每个相邻的脊脊限定纵向腔。 每个室包括在其中延伸的相应导体。 当将多通道神经袖带安装到神经时，脊邻接神经，提供每个腔室以分离神经的各个纵向部分。 还公开了用于制造这种神经箍的方法和装置。
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公开(公告)号：US08214056B2
公开(公告)日：2012-07-03
申请号：US11809934
申请日：2007-06-04
IPC分类号： A61N1/00
CPC分类号： A61N1/0556 , B29C39/10 , B29C45/14426 , Y10T29/49117
摘要： A nerve cuff comprising a wall band member having an inner surface defining a lumen when the wall band member is in a closed configuration for receiving a nerve therethrough. At least one longitudinal and contiguous conductor extends within the lumen. The conductor is insulated and has at least one exposed portion thereby providing an electrode. When mounting the nerve cuff to a nerve, each electrode is in electrical communication with the nerve. A multi-channel nerve cuff further comprises a plurality of longitudinal ridges formed on the inner surface with each adjacent pair of ridges defining a longitudinal chamber. Each chamber comprises a respective conductor extending therein. When mounting the multi-channel nerve cuff to the nerve, the ridges abut the nerve providing for each chamber to isolate respective longitudinal portions of the nerve. A method and an apparatus for manufacturing such nerve cuffs are also disclosed.
摘要翻译： 一种神经套囊，其包括壁带构件，当所述壁带构件处于用于接收神经的闭合构型时，所述壁带构件具有限定内腔的内表面。 至少一个纵向和相邻导体在管腔内延伸。 导体是绝缘的并且具有至少一个暴露部分，从而提供电极。 将神经袖带安装在神经上时，每个电极与神经电连通。 多通道神经套还包括形成在内表面上的多个纵向脊，每个相邻的脊脊限定纵向腔。 每个室包括在其中延伸的相应导体。 当将多通道神经袖带安装到神经时，脊邻接神经，提供每个腔室以分离神经的各个纵向部分。 还公开了用于制造这种神经箍的方法和装置。
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公开(公告)号：US20100047376A1
公开(公告)日：2010-02-25
申请号：US12301582
申请日：2007-08-29
IPC分类号： B29C45/14
CPC分类号： B29C45/2673 , A61N1/0556 , B29C45/0055 , B29C45/03 , B29C45/14065 , B29C45/14426 , B29C45/14639 , B29C2045/0058 , B29K2083/00 , B29L2031/753
摘要： A mold for a nerve cuff having a first molding body defining a first molding cavity and a second molding body defining second molding cavity. The first and second molding bodies being mountable to one another thereby providing for the first and second molding cavities to interface. When interfacing the first and second molding cavities and injecting moldable material therebetween provides the nerve cuff following curing of the moldable material. An industrial mold including interfacing first and second cavities is also disclosed. A removable cassette for interposing between a first and a second molding cavity is also disclosed. Methods of making a nerve cuff are disclosed herein. Nerve cuffs produced by the foregoing molds, cassettes, industrial molds and methods are also disclosed.
摘要翻译： 一种用于神经囊的模具，其具有限定第一模腔的第一模制体和限定第二模腔的第二模制体。 第一和第二成型体可彼此安装，从而为第一和第二模腔提供界面。 当连接第一和第二模腔并注射可模制材料时，在可模制材料固化之后提供神经箍。 还公开了一种包括接合第一和第二腔的工业模具。 还公开了用于插入第一和第二模腔之间的可移动盒。 本文公开了制造神经箍的方法。 还公开了由上述模具，盒，工业模具和方法生产的神经袖口。
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公开(公告)号：US20080065184A1
公开(公告)日：2008-03-13
申请号：US11809934
申请日：2007-06-04
IPC分类号： A61N1/05
CPC分类号： A61N1/0556 , B29C39/10 , B29C45/14426 , Y10T29/49117
摘要： A nerve cuff comprising a wall band member having an inner surface defining a lumen when the wall band member is in a closed configuration for receiving a nerve therethrough. At least one longitudinal and contiguous conductor extends within the lumen. The conductor is insulated and has at least one exposed portion thereby providing an electrode. When mounting the nerve cuff to a nerve, each electrode is in electrical communication with the nerve. A multi-channel nerve cuff further comprises a plurality of longitudinal ridges formed on the inner surface with each adjacent pair of ridges defining a longitudinal chamber. Each chamber comprises a respective conductor extending therein. When mounting the multi-channel nerve cuff to the nerve, the ridges abut the nerve providing for each chamber to isolate respective longitudinal portions of the nerve. A method and an apparatus for manufacturing such nerve cuffs are also disclosed.
摘要翻译： 一种神经套囊，其包括壁带构件，当所述壁带构件处于用于接收神经的闭合构型时，所述壁带构件具有限定内腔的内表面。 至少一个纵向和相邻导体在管腔内延伸。 导体是绝缘的并且具有至少一个暴露部分，从而提供电极。 将神经袖带安装在神经上时，每个电极与神经电连通。 多通道神经套还包括形成在内表面上的多个纵向脊，每个相邻的脊脊限定纵向腔。 每个室包括在其中延伸的相应导体。 当将多通道神经袖带安装到神经时，脊邻接神经，提供每个腔室以分离神经的各个纵向部分。 还公开了用于制造这种神经箍的方法和装置。
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公开(公告)号：US09101679B2
公开(公告)日：2015-08-11
申请号：US12893742
申请日：2010-09-29
申请人： Simon Robitaille , Sylvie Dufresne , Jean-Martin Vallieres , Cynthia Martel , Helene Leblond , Nancy Dassie , Marie-Christine Gagne , Karine Martel , Claudia Bedard , Bruno Tremblay
发明人： Simon Robitaille , Sylvie Dufresne , Jean-Martin Vallieres , Cynthia Martel , Helene Leblond , Nancy Dassie , Marie-Christine Gagne , Karine Martel , Claudia Bedard , Bruno Tremblay
CPC分类号： A61L2/202 , A61L2/20 , A61L2/208 , A61L2202/122 , A61L2202/13 , A61L2202/14 , A61L2202/24 , B65D23/001
摘要： A method of sterilizing an article by sequentially exposing the article to hydrogen peroxide and ozone is disclosed. The article is exposed under vacuum first to an evaporated aqueous solution of hydrogen peroxide and subsequently to an ozone containing gas. The exposure is carried out without reducing the water vapor content of the sterilization atmosphere, the water vapor content being derived from the aqueous solvent of the hydrogen peroxide solution and from the decomposition of the hydrogen peroxide into water and oxygen. The complete sterilization process is carried out while the chamber remains sealed and without removal of any component of the sterilization atmosphere. For this purpose, the chamber is initially evacuated to a first vacuum pressure sufficient to cause evaporation of the aqueous hydrogen peroxide at the temperature of the chamber atmosphere. The chamber is then sealed for the remainder of the sterilization process and during all sterilant injection cycles. Keeping the chamber sealed and maintaining the hydrogen peroxide and its decomposition products in the chamber for the subsequent ozone sterilization step results in a synergistic increase in the sterilization efficiency and allows for the use of much lower sterilant amounts and sterilization cycle times than would be expected from using hydrogen peroxide and ozone in combination.
摘要翻译： 公开了通过将制品依次暴露于过氧化氢和臭氧来对制品进行灭菌的方法。 将该制品首先在真空下暴露于蒸发的过氧化氢水溶液中，随后暴露于含臭氧气体。 曝光是在不降低灭菌气氛的水蒸气含量的情况下进行的，水蒸汽含量来自过氧化氢溶液的水性溶剂和由过氧化氢分解成水和氧气。 在室保持密封且不除去灭菌气氛的任何成分的情况下完成灭菌过程。 为此，腔室最初被抽空到第一真空压力，足以在室气氛的温度下引起过氧化氢水溶液的蒸发。 然后将腔室密封用于灭菌过程的剩余部分和所有灭菌剂注射循环期间。 将室密封并将过氧化氢及其分解产物保持在室中用于随后的臭氧消毒步骤导致灭菌效率的协同增加，并允许使用比预期的更低的杀菌剂量和灭菌循环时间 使用过氧化氢和臭氧组合使用。
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