Sterilization method and apparatus
    1.
    发明授权
    Sterilization method and apparatus 有权
    灭菌方法和装置

    公开(公告)号:US09101679B2

    公开(公告)日:2015-08-11

    申请号:US12893742

    申请日:2010-09-29

    IPC分类号: A61L2/20 B65D23/00

    摘要: A method of sterilizing an article by sequentially exposing the article to hydrogen peroxide and ozone is disclosed. The article is exposed under vacuum first to an evaporated aqueous solution of hydrogen peroxide and subsequently to an ozone containing gas. The exposure is carried out without reducing the water vapor content of the sterilization atmosphere, the water vapor content being derived from the aqueous solvent of the hydrogen peroxide solution and from the decomposition of the hydrogen peroxide into water and oxygen. The complete sterilization process is carried out while the chamber remains sealed and without removal of any component of the sterilization atmosphere. For this purpose, the chamber is initially evacuated to a first vacuum pressure sufficient to cause evaporation of the aqueous hydrogen peroxide at the temperature of the chamber atmosphere. The chamber is then sealed for the remainder of the sterilization process and during all sterilant injection cycles. Keeping the chamber sealed and maintaining the hydrogen peroxide and its decomposition products in the chamber for the subsequent ozone sterilization step results in a synergistic increase in the sterilization efficiency and allows for the use of much lower sterilant amounts and sterilization cycle times than would be expected from using hydrogen peroxide and ozone in combination.

    摘要翻译: 公开了通过将制品依次暴露于过氧化氢和臭氧来对制品进行灭菌的方法。 将该制品首先在真空下暴露于蒸发的过氧化氢水溶液中,随后暴露于含臭氧气体。 曝光是在不降低灭菌气氛的水蒸气含量的情况下进行的,水蒸汽含量来自过氧化氢溶液的水性溶剂和由过氧化氢分解成水和氧气。 在室保持密封且不除去灭菌气氛的任何成分的情况下完成灭菌过程。 为此,腔室最初被抽空到第一真空压力,足以在室气氛的温度下引起过氧化氢水溶液的蒸发。 然后将腔室密封用于灭菌过程的剩余部分和所有灭菌剂注射循环期间。 将室密封并将过氧化氢及其分解产物保持在室中用于随后的臭氧消毒步骤导致灭菌效率的协同增加,并允许使用比预期的更低的杀菌剂量和灭菌循环时间 使用过氧化氢和臭氧组合使用。

    Method and apparatus for ozone sterilization
    2.
    发明授权
    Method and apparatus for ozone sterilization 有权
    臭氧灭菌方法和设备

    公开(公告)号:US07588720B2

    公开(公告)日:2009-09-15

    申请号:US11554763

    申请日:2006-10-31

    摘要: The present invention provides a method and apparatus for sterilizing articles using an ozone-containing gas, where condensation of water from the sterilization atmosphere during the sterilization process is substantially prevented. The inventive sterilization method includes providing a sterilization chamber and placing an article into the sterilization chamber. The sterilization chamber is sealed prior to equalizing the temperature of the article and the atmosphere in the sterilization chamber. A vacuum is applied to achieve a preselected vacuum pressure in the sterilization chamber. Once the vacuum pressure is set, water vapour is supplied to the sterilization chamber. Ozone-containing gas is then supplied to the sterilization chamber and the sterilization chamber remains sealed for a preselected treatment period, where the sterilization chamber remains sealed throughout the whole process. Finally, vacuum in the sterilization chamber is released.

    摘要翻译: 本发明提供一种使用含臭氧气体灭菌物品的方法和装置,其中基本上防止了在灭菌过程中来自灭菌气氛的水的冷凝。 本发明的灭菌方法包括提供灭菌室并将物品放入灭菌室。 在均匀化灭菌室内物品的温度和气氛之前密封灭菌室。 施加真空以在灭菌室中实现预选的真空压力。 一旦设定了真空压力,则向灭菌室供给水蒸汽。 然后将含臭氧气体供应到灭菌室,并且灭菌室在预选的处理期间保持密封,其中在整个过程中消毒室保持密封。 最后,消毒室中的真空被释放。

    STERILIZATION METHOD AND APPARATUS
    3.
    发明申请
    STERILIZATION METHOD AND APPARATUS 有权
    杀菌方法和装置

    公开(公告)号:US20110076192A1

    公开(公告)日:2011-03-31

    申请号:US12893742

    申请日:2010-09-29

    IPC分类号: A61L2/16 B65D90/02

    摘要: A method of sterilizing an article by sequentially exposing the article to hydrogen peroxide and ozone is disclosed. The article is exposed under vacuum first to an evaporated aqueous solution of hydrogen peroxide and subsequently to an ozone containing gas. The exposure is carried out without reducing the water vapor content of the sterilization atmosphere, the water vapor content being derived from the aqueous solvent of the hydrogen peroxide solution and from the decomposition of the hydrogen peroxide into water and oxygen. The complete sterilization process is carried out while the chamber remains sealed and without removal of any component of the sterilization atmosphere. For this purpose, the chamber is initially evacuated to a first vacuum pressure sufficient to cause evaporation of the aqueous hydrogen peroxide at the temperature of the chamber atmosphere. The chamber is then sealed for the remainder of the sterilization process and during all sterilant injection cycles. Keeping the chamber sealed and maintaining the hydrogen peroxide and its decomposition products in the chamber for the subsequent ozone sterilization step results in a synergistic increase in the sterilization efficiency and allows for the use of much lower sterilant amounts and sterilization cycle times than would be expected from using hydrogen peroxide and ozone in combination.

    摘要翻译: 公开了通过将制品依次暴露于过氧化氢和臭氧来对制品进行灭菌的方法。 将该制品首先在真空下暴露于蒸发的过氧化氢水溶液中,随后暴露于含臭氧气体。 曝光是在不降低灭菌气氛的水蒸气含量的情况下进行的,水蒸汽含量来自过氧化氢溶液的水性溶剂和由过氧化氢分解成水和氧气。 在室保持密封且不除去灭菌气氛的任何成分的情况下完成灭菌过程。 为此,腔室最初被抽空到第一真空压力,足以在室气氛的温度下引起过氧化氢水溶液的蒸发。 然后将腔室密封用于灭菌过程的剩余部分和所有灭菌剂注射循环期间。 将室密封并将过氧化氢及其分解产物保持在室中用于随后的臭氧消毒步骤导致灭菌效率的协同增加,并允许使用比预期的更低的杀菌剂量和灭菌循环时间 使用过氧化氢和臭氧组合使用。

    Method and apparatus for ozone sterilization

    公开(公告)号:US07128872B2

    公开(公告)日:2006-10-31

    申请号:US10005786

    申请日:2001-11-08

    CPC分类号: A61L2/20 A61L2/202 A61L2/24

    摘要: The sterilization method disclosed includes the steps of providing a sterilization chamber; placing the article into the sterilization chamber; equalizing the temperature of the article and the sterilization atmosphere; sealing the sterilization chamber; applying a vacuum of a preselected vacuum pressure to the sterilization chamber; supplying water vapour to the sterilization chamber under vacuum; supplying ozone-containing gas to the sterilization chamber; maintaining the sterilization chamber sealed for a preselected treatment period; and releasing the vacuum in the sterilization chamber; whereby a vacuum pressure is used which lowers the boiling temperature of water in the sterilization chamber below the temperature in the sterilization chamber. One or more ventilating cycles can be added to the preferred method for removing the remaining ozone and humidity from the sterilization chamber. Single cycle sterilization with ozone is more efficient and provides for a shorter sterilization cycle than with ETO and requires few changes in user habits. Moreover, the ozone-based process in accordance with the invention is compatible for use with current packaging, such as sterile pouches and rigid containers. The sterilization process is simple and substantially avoids human errors caused by false interpretation and handling. The ozone sterilization method of the invention requires substantially no aeration or cooling down of sterilized instruments so that they can be used immediately following the sterilization cycle. This allows hospitals to reduce the cost of maintaining expensive medical device inventories.

    Method and apparatus for ozone sterilization
    5.
    发明申请
    Method and apparatus for ozone sterilization 有权
    臭氧灭菌方法和设备

    公开(公告)号:US20070258855A1

    公开(公告)日:2007-11-08

    申请号:US11554763

    申请日:2006-10-31

    IPC分类号: A61L2/20 B01J19/00

    摘要: The present invention provides a method and apparatus for sterilizing articles using an ozone-containing gas, where condensation of water from the sterilization atmosphere during the sterilization process is substantially prevented. The inventive sterilization method includes providing a sterilization chamber and placing an article into the sterilization chamber. The sterilization chamber is sealed prior to equalizing the temperature of the article and the atmosphere in the sterilization chamber. A vacuum is applied to achieve a preselected vacuum pressure in the sterilization chamber. Once the vacuum pressure is set, water vapour is supplied to the sterilization chamber. Ozone-containing gas is then supplied to the sterilization chamber and the sterilization chamber remains sealed for a preselected treatment period, where the sterilization chamber remains sealed throughout the whole process. Finally, vacuum in the sterilization chamber is released.

    摘要翻译: 本发明提供一种使用含臭氧气体对制品进行灭菌的方法和装置,其中基本上防止了在灭菌过程中来自灭菌气氛的水的冷凝。 本发明的灭菌方法包括提供灭菌室并将物品放入灭菌室。 在均匀化灭菌室内物品的温度和气氛之前密封灭菌室。 施加真空以在灭菌室中实现预选的真空压力。 一旦设定了真空压力,则向灭菌室供给水蒸汽。 然后将含臭氧气体供应到灭菌室,并且灭菌室在预选的处理期间保持密封,其中在整个过程中消毒室保持密封。 最后,消毒室中的真空被释放。