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公开(公告)号:US20050223416A1
公开(公告)日:2005-10-06
申请号:US11087789
申请日:2005-03-22
申请人: Johannes Nuijens , Henricus Van Veen , Frank Pieper , Joris Heus
发明人: Johannes Nuijens , Henricus Van Veen , Frank Pieper , Joris Heus
IPC分类号: A01K67/027 , A23L1/305 , A61K38/00 , A61K38/55 , A61P9/00 , A61P9/10 , A61P17/02 , A61P29/00 , A61P31/04 , A61P37/06 , C07K14/81 , C12N15/09 , C12N15/85 , A61K38/54
CPC分类号: C07K14/8121 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2227/105 , A01K2227/107 , A01K2267/01 , A23C2230/05 , A61K38/00 , C12N15/8509
摘要: The invention provides transgenic nonhuman mammals expressing C1 inhibitor in their milk. The C1 inhibitor is useful in treating patients with hereditary angioedema or patients requiring immunosuppression.
摘要翻译: 本发明提供了在其乳中表达C1抑制剂的转基因非人哺乳动物。 C1抑制剂可用于治疗遗传性血管性水肿患者或需要免疫抑制的患者。