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1.
公开(公告)号:US08034899B2
公开(公告)日:2011-10-11
申请号:US12254259
申请日:2008-10-20
申请人: John Dwyer , Brian L. Bray , Stephen E. Schneider , Huyi Zhang , Nicolai A. Tvermoes , Barbara E. Johnston , Paul E. Friedrich
发明人: John Dwyer , Brian L. Bray , Stephen E. Schneider , Huyi Zhang , Nicolai A. Tvermoes , Barbara E. Johnston , Paul E. Friedrich
CPC分类号: C07K14/005 , A61K38/00 , C12N2740/16022 , C12N2740/16122 , G01N2333/16 , G01N2800/26
摘要: Provided is an HIV fusion inhibitor peptide having an amino acid sequence of any one of SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, or SEQ ID NO:15; and provided is a pharmaceutical composition comprising a HIV fusion inhibitor peptide and one or more of a pharmaceutically acceptable carrier and macromolecular carrier, and uses and methods of treatment provided by these compositions.
摘要翻译: 本发明提供了具有SEQ ID NO:9,SEQ ID NO:10,SEQ ID NO:11,SEQ ID NO:12,SEQ ID NO:13,SEQ ID NO: 14或SEQ ID NO:15; 并且提供了包含HIV融合抑制剂肽和药学上可接受的载体和大分子载体中的一种或多种的药物组合物,以及由这些组合物提供的用途和治疗方法。
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2.
公开(公告)号:US20090105143A1
公开(公告)日:2009-04-23
申请号:US12254259
申请日:2008-10-20
申请人: John J. Dwyer , Brian L. Bray , Stephen E. Schneider , Huyi Zhang , Nicolai A. Tvermoes , Barbara E. Johnston , Paul E. Friedrich
发明人: John J. Dwyer , Brian L. Bray , Stephen E. Schneider , Huyi Zhang , Nicolai A. Tvermoes , Barbara E. Johnston , Paul E. Friedrich
CPC分类号: C07K14/005 , A61K38/00 , C12N2740/16022 , C12N2740/16122 , G01N2333/16 , G01N2800/26
摘要: Provided is an HIV fusion inhibitor peptide having an amino acid sequence of any one of SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, or SEQ ID NO:15; and provided is a pharmaceutical composition comprising a HIV fusion inhibitor peptide and one or more of a pharmaceutically acceptable carrier and macromolecular carrier, and uses and methods of treatment provided by these compositions.
摘要翻译: 本发明提供了具有SEQ ID NO:9,SEQ ID NO:10,SEQ ID NO:11,SEQ ID NO:12,SEQ ID NO:13,SEQ ID NO: 14或SEQ ID NO:15; 并且提供了包含HIV融合抑制剂肽和药学上可接受的载体和大分子载体中的一种或多种的药物组合物,以及由这些组合物提供的用途和治疗方法。
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公开(公告)号:US20100261876A1
公开(公告)日:2010-10-14
申请号:US12679609
申请日:2008-09-25
申请人: Brian L. Bray , Barbara E. Johnston , Stephen E. Schneider , Nicolai A. Tvermoes , Huyi Zhang , Paul E. Friedrich
发明人: Brian L. Bray , Barbara E. Johnston , Stephen E. Schneider , Nicolai A. Tvermoes , Huyi Zhang , Paul E. Friedrich
CPC分类号: C07K14/005 , A61K38/00 , C07K2319/00 , C12N2740/16122
摘要: Provided herein are methods for synthesis of peptides. In particular, provided herein are methods of synthesis for therapeutic antiviral peptides.
摘要翻译: 本文提供了合成肽的方法。 特别地,本文提供了治疗性抗病毒肽的合成方法。
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4.
公开(公告)号:US20120040891A1
公开(公告)日:2012-02-16
申请号:US13222766
申请日:2011-08-31
申请人: John J. Dwyer , Brian L. Bray , Stephen E. Schneider , Huyi Zhang , Nicolai A. Tvermoes , Barbara E. Johnston , Paul E. Friedrich
发明人: John J. Dwyer , Brian L. Bray , Stephen E. Schneider , Huyi Zhang , Nicolai A. Tvermoes , Barbara E. Johnston , Paul E. Friedrich
CPC分类号: C07K14/005 , A61K38/00 , C12N2740/16022 , C12N2740/16122 , G01N2333/16 , G01N2800/26
摘要: Provided is an HIV fusion inhibitor peptide having an amino acid sequence of any one of SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, or SEQ ID NO:15; and provided is a pharmaceutical composition comprising a HIV fusion inhibitor peptide and one or more of a pharmaceutically acceptable carrier and macromolecular carrier, and uses and methods of treatment provided by these compositions.
摘要翻译: 本发明提供了具有SEQ ID NO:9,SEQ ID NO:10,SEQ ID NO:11,SEQ ID NO:12,SEQ ID NO:13,SEQ ID NO: 14或SEQ ID NO:15; 并且提供了包含HIV融合抑制剂肽和药学上可接受的载体和大分子载体中的一种或多种的药物组合物,以及由这些组合物提供的用途和治疗方法。
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