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1.
公开(公告)号:US20120004202A1
公开(公告)日:2012-01-05
申请号:US13077138
申请日:2011-03-31
申请人: John Edward PARK , Nveed CHAUDHARY , Gerald Juergen ROTH , Armin HECKEL , Thorsten LEHMANN-LINTZ , Joerg KLEY
发明人: John Edward PARK , Nveed CHAUDHARY , Gerald Juergen ROTH , Armin HECKEL , Thorsten LEHMANN-LINTZ , Joerg KLEY
IPC分类号: A61K31/4045 , A61K31/4178 , A61K31/4439 , A61K31/5377 , A61K31/541 , A61P17/00 , A61P11/00 , A61P11/06 , A61P29/00 , A61P1/16 , A61P13/12 , A61K31/496 , A61K31/56
CPC分类号: A61K31/496 , A61K31/404 , A61K31/4178 , C07D209/34 , C07D403/06
摘要: The present invention relates to the use of indolinones of general formula substituted in the 6 position, wherein R1 to R6 and X are defined as in claim 1, the isomers and the salts thereof, particularly the physiologically acceptable salts thereof, as a medicament for the prevention or treatment of specific fibrotic diseases.
摘要翻译: 本发明涉及在6位上被取代的通式的二氢吲哚酮的用途,其中R 1至R 6和X如权利要求1中所定义,其异构体及其盐,特别是其生理上可接受的盐作为药物用于 预防或治疗特定的纤维化疾病。
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2.
公开(公告)号:US20140128409A1
公开(公告)日:2014-05-08
申请号:US14153542
申请日:2014-01-13
申请人: John Edward PARK , Nveed CHAUDHARY , Gerald Juergen ROTH , Armin HECKEL , Thorsten LEHMANN-LINTZ , Joerg KLEY
发明人: John Edward PARK , Nveed CHAUDHARY , Gerald Juergen ROTH , Armin HECKEL , Thorsten LEHMANN-LINTZ , Joerg KLEY
IPC分类号: A61K31/496 , C07D403/06 , A61K31/4178 , A61K31/404 , C07D209/34
CPC分类号: A61K31/496 , A61K31/404 , A61K31/4178 , C07D209/34 , C07D403/06
摘要: The present invention relates to the use of indolinones of general formula substituted in the 6 position, wherein R1 to R6 and X are defined as in claim 1, the isomers and the salts thereof, particularly the physiologically acceptable salts thereof, as a medicament for the prevention or treatment of specific fibrotic diseases.
摘要翻译: 本发明涉及在6位上被取代的通式的二氢吲哚酮的用途,其中R 1至R 6和X如权利要求1中所定义,其异构体及其盐,特别是其生理上可接受的盐作为药物用于 预防或治疗特定的纤维化疾病。
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3.
公开(公告)号:US20100204211A1
公开(公告)日:2010-08-12
申请号:US12645151
申请日:2009-12-22
申请人: John Edward PARK , Gerald Juergen ROTH , Armin HECKEL , Nveed CHAUDHARY , Trixi BRANDL , Georg DAHMANN , Matthias GRAUERT
发明人: John Edward PARK , Gerald Juergen ROTH , Armin HECKEL , Nveed CHAUDHARY , Trixi BRANDL , Georg DAHMANN , Matthias GRAUERT
IPC分类号: A61K31/496 , A61K31/404 , A61K31/551 , A61K31/5377 , A61P11/00
CPC分类号: A61K31/4045 , A61K31/404 , A61K31/4178 , A61K31/44 , A61K31/445 , A61K31/454 , A61K31/495 , A61K31/496 , A61K31/5377 , A61K31/551 , A61K45/06 , C07D209/34 , C07D295/155 , C07D295/215 , C07D401/12 , C07D403/12 , A61K2300/00
摘要: The present invention relates to the use of indolinones of general formula substituted in the 6 position, wherein R1 to R5 and X are defined as in claim 1, the isomers and the salts thereof, particularly the physiologically acceptable salts thereof, as a medicament for the prevention or treatment of specific fibrotic diseases.
摘要翻译: 本发明涉及在6位上被取代的通式的二氢吲哚酮的用途,其中R 1至R 5和X如权利要求1中所定义,其异构体及其盐,特别是其生理上可接受的盐作为药物用于 预防或治疗特定的纤维化疾病。
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4.
公开(公告)号:US20140296217A1
公开(公告)日:2014-10-02
申请号:US14184821
申请日:2014-02-20
申请人: John Edward PARK , Gerald Juergen ROTH , Armin HECKEL , Nveed CHAUDHARY , Trixi BRANDL , Georg DAHMANN , Matthias GRAUERT
发明人: John Edward PARK , Gerald Juergen ROTH , Armin HECKEL , Nveed CHAUDHARY , Trixi BRANDL , Georg DAHMANN , Matthias GRAUERT
IPC分类号: C07D209/34 , C07D403/12 , A61K31/4045 , A61K31/454 , A61K31/5377 , A61K31/496 , A61K45/06 , A61K31/551 , C07D401/12 , A61K31/4178
CPC分类号: A61K31/4045 , A61K31/404 , A61K31/4178 , A61K31/44 , A61K31/445 , A61K31/454 , A61K31/495 , A61K31/496 , A61K31/5377 , A61K31/551 , A61K45/06 , C07D209/34 , C07D295/155 , C07D295/215 , C07D401/12 , C07D403/12 , A61K2300/00
摘要: The present invention relates to the use of indolinones of general formula substituted in the 6 position, wherein R1 to R5 and X are defined as in claim 1, the isomers and the salts thereof, particularly the physiologically acceptable salts thereof, as a medicament for the prevention or treatment of specific fibrotic diseases.
摘要翻译: 本发明涉及在6位上被取代的通式的二氢吲哚酮的用途,其中R 1至R 5和X如权利要求1中所定义,其异构体及其盐,特别是其生理上可接受的盐作为药物用于 预防或治疗特定的纤维化疾病。
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公开(公告)号:US20110076238A1
公开(公告)日:2011-03-31
申请号:US12963250
申请日:2010-12-08
IPC分类号: A61K31/439 , A61K9/12 , A61P35/00
CPC分类号: A61K31/46 , A61K31/135
摘要: The invention relates to the use of anticholinergics for preparing a pharmaceutical composition for the prevention and treatment of proliferative processes.
摘要翻译: 本发明涉及抗胆碱能药物用于制备用于预防和治疗增殖过程的药物组合物的用途。
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