公开(公告)号：US07332185B2

公开(公告)日：2008-02-19

申请号：US10280198

申请日：2002-10-24

申请人： John G. Babish ,  M. Terrence Howell

发明人： John G. Babish ,  M. Terrence Howell

IPC分类号： A01N65/00

CPC分类号： A61K31/00 ,  A23L33/10 ,  A61K31/12 ,  A61K45/06 ,  A61K2300/00

摘要： A novel formulation is provided that serves to specifically inhibit the COX-2 mediated inflammation response in animals. The formulation comprises comprising an effective amount of component I selected from the group consisting of alpha acids and beta acids and an effective amount of at least one component II selected from the group consisting of alpha acids, beta acids, essential oils, fats and waxes, with the proviso that component I and II are not the same compound. The composition provides specific inhibition of cyclooxygenase-2 with little or no effect on cyclooxygenase-1.

摘要翻译： 提供了一种用于特异性抑制COX-2介导的动物炎症反应的新型制剂。 该制剂包含有效量的选自α酸和β酸的组分I和有效量的至少一种选自α酸，β酸，精油，脂肪和蜡的组分II， 条件是组分I和II不是相同的化合物。 该组合物对环加氧酶-2的特异性抑制作用，对环氧合酶-1几乎没有或没有影响。

公开(公告)号：US07205151B2

公开(公告)日：2007-04-17

申请号：US09885721

申请日：2001-06-20

申请人： John G. Babish ,  M. Terrence Howell

发明人： John G. Babish ,  M. Terrence Howell

IPC分类号： A01N35/78

CPC分类号： A61K31/00 ,  A23L33/10 ,  A61K31/12 ,  A61K45/06 ,  A61K2300/00

摘要： A novel formulation is provided that serves to specifically inhibit the COX-2 mediated inflammatory response in animals. The formulation comprises an effective amount of component I selected from the group consisting of alpha acids and beta acids and an effective amount of at least one component II selected from the group consisting of alpha acids, beta acids, essential oils, fats and waxes, with the proviso that component I and II are not the same compound. The composition provides specific inhibition of cyclooxygenase-2 with little or no effect on cyclooxygenase-1.

摘要翻译： 提供了用于特异性抑制动物中COX-2介导的炎性反应的新型制剂。 该制剂包含有效量的选自α酸和β酸的组分I和有效量的至少一种选自α酸，β酸，精油，脂肪和蜡的组分II，其中 条件是组分I和II不是相同的化合物。 该组合物对环加氧酶-2的特异性抑制作用，对环氧合酶-1几乎没有或没有影响。