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    Pharmaceutical use of substituted amides
    2.
    发明申请
    Pharmaceutical use of substituted amides 审中-公开
    药物使用取代酰胺

    公开(公告)号：US20080108598A1

    公开(公告)日：2008-05-08

    申请号：US12006765

    申请日：2008-01-03

    申请人： Henrik Andersen ,  Gita Camilla Kampen ,  Inge Christensen ,  John Mogensen ,  Annette Larsen ,  John Kilburn

    发明人： Henrik Andersen ,  Gita Camilla Kampen ,  Inge Christensen ,  John Mogensen ,  Annette Larsen ,  John Kilburn

    IPC分类号： A61K31/55 ,  A61P3/10

    CPC分类号： A61K45/06 ,  A61K31/16 ,  A61K31/415 ,  C07D209/02 ,  C07D401/06 ,  C07D401/12 ,  C07D403/12 ,  C07D487/08

    摘要： The use of substituted amides for modulating the activity of 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) and the use of these compounds as pharmaceutical compositions, are described. Also a novel class of substituted amides, their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments are described. The present compounds are modulators and more specifically inhibitors of the activity of 11βHSD1 and may be useful in the treatment, prevention and/or prophylaxis of a range of medical disorders where a decreased intracellular concentration of active glucocorticoid is desirable.

    摘要翻译： 描述了使用取代的酰胺调节11β-羟类固醇脱氢酶1型（11betaHSD1）的活性以及这些化合物作为药物组合物的用途。 还描述了一类新颖的取代的酰胺，它们在治疗中的用途，包含该化合物的药物组合物及其在制备药物中的用途。 本发明化合物是调节剂，更具体地是11betaHSD1活性的抑制剂，并且可用于治疗，预防和/或预防一系列需要活性糖皮质激素的细胞内浓度降低的医学疾病。

    Shelf talker having short and long term information
    3.
    发明申请
    Shelf talker having short and long term information 失效
    具有短期和长期信息的货架谈话者

    公开(公告)号：US20050030157A1

    公开(公告)日：2005-02-10

    申请号：US10633714

    申请日：2003-08-04

    申请人： Robert Capurso ,  James Papa ,  John Kilburn

    发明人： Robert Capurso ,  James Papa ,  John Kilburn

    IPC分类号： G06Q30/00 ,  G09G3/18 ,  H04Q1/00

    CPC分类号： G06Q30/06 ,  G09G3/18 ,  G09G2380/04

    摘要： A shelf talker for displaying short and longer term information includes a backplane including a plurality of electrical conductors; a plurality of single character display chips mounted on the backplane in electrical contact with the electrical conductors for displaying the short term information; and a graphic overlay located over the backplane bearing the longer term information and defining apertures for displaying the short term information displayed by the single character display chips.

    摘要翻译： 用于显示短期和长期信息的货架谈话者包括一个包括多个电导体的背板; 安装在所述背板上与所述电导体电接触以显示所述短期信息的多个单字显示芯片; 以及位于背板上的图形覆盖物，其具有较长期信息并且限定用于显示由单个字符显示芯片显示的短期信息的孔。

    Reflectance-matching layer for cholesteric display having dye layer and reflective conductors
    6.
    发明申请
    Reflectance-matching layer for cholesteric display having dye layer and reflective conductors 审中-公开
    具有染料层和反射导体的胆甾型显示器的反射匹配层

    公开(公告)号：US20050253987A1

    公开(公告)日：2005-11-17

    申请号：US10847188

    申请日：2004-05-17

    申请人： Stanley Stephenson ,  John Kilburn ,  Terry Martin

    发明人： Stanley Stephenson ,  John Kilburn ,  Terry Martin

    IPC分类号： G02F1/1335 ,  G02F1/137

    CPC分类号： G02F1/133512 ,  G02F1/13718

    摘要： A display sheet comprises in order a substrate, transparent first conductors, a light-modulating material having different first and second field-changeable stable optical states, a light-absorbing layer that absorbs a portion of the visible spectrum and transmits a portion of the visible spectrum, substantially reflective second conductors forming conductive segments that operate in conjunction with the light-absorbing layer to provide reflective light additional to that provided by the light-modulating material, and substantially reflective non-conductive material, disposed over one or more background areas of light-absorbing layer not covered by second conductors, to provide reflective light additional to that provided by the light-modulating material such that the total reflected light in background areas more closely match the total reflected light in the segmented areas when both areas are in the same optical state

    摘要翻译： 显示片依次包括衬底，透明第一导体，具有不同的第一和第二场变化的稳定光学状态的光调制材料，吸收可见光谱的一部分并透射可见光的一部分的光吸收层 形成导电段的基本上反射的第二导体，其与光吸收层一起工作以提供除由光调制材料提供的反射光之外的反射光，以及设置在一个或多个背景区域上的基本上反射的非导电材料 光吸收层未被第二导体覆盖，以提供除了由光调制材料提供的光附加的反射光，使得当两个区域都在该区域中时，背景区域中的总反射光更接近匹配分段区域中的总反射光 相同的光学状态