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公开(公告)号:US20070021422A1
公开(公告)日:2007-01-25
申请号:US11374683
申请日:2006-06-27
申请人: John Mabus , Jeffrey Palmer , Stephen Prouty , Pamela Hornby , Paul Wade
发明人: John Mabus , Jeffrey Palmer , Stephen Prouty , Pamela Hornby , Paul Wade
IPC分类号: A61K31/53 , A61K31/513
CPC分类号: A61K31/513 , A61K31/53 , C07D239/545 , C07D251/46
摘要: The present invention relates to methods of monitoring the biological activity of the PK1 receptor.
摘要翻译: 本发明涉及监测PK1受体的生物学活性的方法。
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2.METHODS, KITS, AND COMPOSITIONS FOR GENERATING NEW HAIR FOLLICLES AND GROWING HAIR 有权
标题翻译: 用于产生新的头发毛发和生长头发的方法,用具和组合物公开(公告)号:US20100120768A1
公开(公告)日:2010-05-13
申请号:US12443122
申请日:2007-09-27
IPC分类号: A61K31/5377 , A61K31/135 , A61K31/203 , A61K31/496 , A61K31/436 , A61K31/506 , A61K31/155 , A61K31/435 , A61P17/14
CPC分类号: A61K9/0014 , A61K8/02 , A61K8/70 , A61K2800/782 , A61K2800/91 , A61Q7/00
摘要: The invention features methods, kits, and compositions for generating new hair follicles and growing hair on a subject.
摘要翻译: 本发明的特征在于产生新毛囊和在受试者上生长头发的方法,试剂盒和组合物。
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3.HETEROAROMATIC AND AROMATIC PIPERAZINYL AZETIDINYL AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS 有权
标题翻译: 异佛尔酮和维生素A亚胺基酰胺作为单糖胆碱酯酶抑制剂公开(公告)号:US20100324015A1
公开(公告)日:2010-12-23
申请号:US12765617
申请日:2010-04-22
申请人: Kristen Chevalier , Jose Clemente , Scott Dax , Chris Flores , Li Liu , Mark Macielag , Mark McDonnell , Marina Nelen , Erica Nulton , Stephen Prouty , Matthew Todd , Sui-Po Zhang , Bin Zhu
发明人: Kristen Chevalier , Jose Clemente , Scott Dax , Chris Flores , Li Liu , Mark Macielag , Mark McDonnell , Marina Nelen , Erica Nulton , Stephen Prouty , Matthew Todd , Sui-Po Zhang , Bin Zhu
IPC分类号: A61K31/496 , C07D403/14 , A61K31/506 , C07D401/14 , C07D417/14 , C07D413/14 , A61P29/00 , A61P1/04 , A61P25/00
CPC分类号: C07D413/14 , C07D205/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/14 , C07D409/14 , C07D413/12 , C07D417/12
摘要: Disclosed are compounds, compositions and methods for treating diseases, syndromes, conditions and disorders that are affected by the inhibition of MGL, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, r, R2 and Z are defined herein.
摘要翻译: 公开了用于治疗受到抑制MGL(包括疼痛)的疾病,综合征,病症和障碍的化合物,组合物和方法。 这样的化合物由式(I)表示如下:其中Y,r,R 2和Z如本文所定义。
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公开(公告)号:US06844510B2
公开(公告)日:2005-01-18
申请号:US10638966
申请日:2003-08-11
申请人: Stephen Prouty , Steven Kille , Charles McCall , Kevin Shell , Jack Tseng , Art Stephen
发明人: Stephen Prouty , Steven Kille , Charles McCall , Kevin Shell , Jack Tseng , Art Stephen
CPC分类号: B60Q1/1469
摘要: A stalk switch having an energy storage element disposed coxially about a handle to store energy when the handle is in a contact position and release energy to provide a force to drive the handle back to the neutral position from the contact position. The energy storage element may be a sleeve made of an elastomeric material. Such a sleeve may also provide for overload protection for contact closures of the switch. The stalk switch may also have at least one microswitch to align operation of a contact closure with actual motion of the handle.
摘要翻译: 一种具有能量存储元件的杆开关,所述能量存储元件在手柄处于接触位置的同时位于手柄处以存储能量并且释放能量以提供力以将手柄从接触位置驱动回到中立位置。 储能元件可以是由弹性材料制成的套筒。 这种套筒还可以为开关的接触闭合提供过载保护。 杆开关还可以具有至少一个微动开关,以将触点闭合的操作与手柄的实际运动对准。
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5.Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors 有权
标题翻译: 杂芳基和芳香哌嗪基氮杂环丁烷酰胺作为单酰基甘油脂肪酶抑制剂公开(公告)号:US08415341B2
公开(公告)日:2013-04-09
申请号:US12765617
申请日:2010-04-22
申请人: Kristen Chevalier , Jose Clemente , Scott Dax , Chris Flores , Li Liu , Mark Macielag , Mark McDonnell , Marina Nelen , Erica Nulton , Stephen Prouty , Matthew Todd , Sui-Po Zhang , Bin Zhu
发明人: Kristen Chevalier , Jose Clemente , Scott Dax , Chris Flores , Li Liu , Mark Macielag , Mark McDonnell , Marina Nelen , Erica Nulton , Stephen Prouty , Matthew Todd , Sui-Po Zhang , Bin Zhu
IPC分类号: A61K31/496 , A61K31/551 , C07D401/06 , C07D401/14 , C07D403/12 , C07D409/14 , C07D417/12
CPC分类号: C07D413/14 , C07D205/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/14 , C07D409/14 , C07D413/12 , C07D417/12
摘要: Disclosed are compounds, compositions and methods for treating diseases, syndromes, conditions and disorders that are affected by the inhibition of MGL, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, r, R2 and Z are defined herein.
摘要翻译: 公开了用于治疗受到抑制MGL(包括疼痛)的疾病,综合征,病症和障碍的化合物,组合物和方法。 这样的化合物由式(I)表示如下:其中Y,r,R 2和Z如本文所定义。
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6.HETEROAROMATIC AND AROMATIC PIPERAZINYL AZETIDINYL AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS 有权
标题翻译: 异佛尔酮和维生素A亚胺基酰胺作为单糖胆碱酯酶抑制剂公开(公告)号:US20100324016A1
公开(公告)日:2010-12-23
申请号:US12765675
申请日:2010-04-22
申请人: Chris FLORES , Marina Nelen , Erica Nulton , Stephen Prouty , Matthew Todd , Sui-Po Zhang
发明人: Chris FLORES , Marina Nelen , Erica Nulton , Stephen Prouty , Matthew Todd , Sui-Po Zhang
IPC分类号: A61K31/496 , C07D401/14 , C07D403/12 , C07D413/14 , A61P29/00 , A61P1/04 , A61P25/00
CPC分类号: C07D413/14 , C07D205/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/14 , C07D409/14 , C07D413/12 , C07D417/12
摘要: Disclosed are compounds, compositions and methods for treating diseases, syndromes, conditions and disorders that are affected by the inhibition of MGL, including pain. Such compounds are represented by Formula (I) as follows: wherein R1, W and are defined herein.
摘要翻译: 公开了用于治疗受到抑制MGL(包括疼痛)的疾病,综合征,病症和障碍的化合物,组合物和方法。 这样的化合物由式(I)表示如下:其中R1,W和本文定义。
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7.Methods, kits, and compositions for generating new hair follicles and growing hair 有权
标题翻译: 用于产生新毛囊和生长头发的方法,试剂盒和组合物公开(公告)号:US08252749B2
公开(公告)日:2012-08-28
申请号:US12443122
申请日:2007-09-27
IPC分类号: A61K38/00
CPC分类号: A61K9/0014 , A61K8/02 , A61K8/70 , A61K2800/782 , A61K2800/91 , A61Q7/00
摘要: The invention features methods, kits, and compositions for generating new hair follicles and growing hair on a subject.
摘要翻译: 本发明的特征在于产生新毛囊和在受试者上生长头发的方法,试剂盒和组合物。
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8.Methods, Kits, and Compositions for Generating New Hair Follicles and Growing Hair 审中-公开
标题翻译: 用于产生新毛囊和生长发的方法,试剂盒和组合物公开(公告)号:US20120156228A1
公开(公告)日:2012-06-21
申请号:US13229008
申请日:2011-09-09
IPC分类号: A61K39/00 , A61K31/33 , A61K31/5377 , A61K31/517 , A61P37/06 , A61K31/42 , A61P31/04 , A61P31/00 , A61P37/08 , A61P29/00 , A61K31/56 , A61K31/505
CPC分类号: A61K9/0014 , A61K8/02 , A61K8/70 , A61K2800/782 , A61K2800/91 , A61Q7/00
摘要: The invention features methods, kits, and compositions for generating new hair follicles and growing hair on a subject.
摘要翻译: 本发明的特征在于产生新毛囊和在受试者上生长头发的方法,试剂盒和组合物。
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9.Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors 有权
标题翻译: 杂芳基和芳香哌嗪基氮杂环丁烷酰胺作为单酰基甘油脂肪酶抑制剂公开(公告)号:US08435977B2
公开(公告)日:2013-05-07
申请号:US12765675
申请日:2010-04-22
申请人: Chris Flores , Marina Nelen , Erica Nulton , Stephen Prouty , Matthew Todd , Sui-Po Zhang
发明人: Chris Flores , Marina Nelen , Erica Nulton , Stephen Prouty , Matthew Todd , Sui-Po Zhang
IPC分类号: A61K31/496
CPC分类号: C07D413/14 , C07D205/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/14 , C07D409/14 , C07D413/12 , C07D417/12
摘要: Disclosed are compounds, compositions and methods for treating diseases, syndromes, conditions and disorders that are affected by the inhibition of MGL, including pain. Such compounds are represented by Formula (I) as follows: wherein R1, W and are defined herein.
摘要翻译: 公开了用于治疗受到抑制MGL(包括疼痛)的疾病,综合征,病症和障碍的化合物,组合物和方法。 这样的化合物由式(I)表示如下:其中R1,W和本文定义。
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