公开(公告)号：US5141870A

公开(公告)日：1992-08-25

申请号：US642976

申请日：1991-01-18

申请人： John R. Bedbrook ,  Roy S. Chaleff ,  Saverio C. Falco ,  Barbara J. Mazur ,  Cristopher R. Somerville ,  Narendra S. Yadav

发明人： John R. Bedbrook ,  Roy S. Chaleff ,  Saverio C. Falco ,  Barbara J. Mazur ,  Cristopher R. Somerville ,  Narendra S. Yadav

IPC分类号： C12N9/88 ,  C12N15/82

CPC分类号： C12N9/88 ,  C12N15/8278

摘要： A nucleic acid fragment encoding a herbicide-resistant plant acetolactate synthase protein is disclosed. This nucleic acid fragment contains at least one nucleotide mutation resulting in one amino acid change in one of seven substantially conserved regions of acetolactate synthase amino acid homology. This mutation results in the production of an acetolactate synthase protein which is resistant to sulfonylurea herbicide compounds compared to the wild-type protin. Transformation of herbicide sensitive plants or plant cells with the fragment results in resistance to the herbicide.

摘要翻译： 公开了编码除草剂抗性植物乙酰乳酸合酶蛋白的核酸片段。 该核酸片段含有至少一个核苷酸突变，导致乙酰乳酸合酶氨基酸同源性的七个基本上保守的区域之一发生一个氨基酸变化。 与野生型蛋白相比，该突变导致对磺酰脲类除草剂化合物具有抗性的乙酰乳酸合酶蛋白。 用片段转化除草剂敏感植物或植物细胞导致对除草剂的抗性。