-
公开(公告)号:US20100143438A1
公开(公告)日:2010-06-10
申请号:US12515514
申请日:2007-11-19
申请人: John Simon Todd , Vincent Rein Ulijn , Julie Gough
发明人: John Simon Todd , Vincent Rein Ulijn , Julie Gough
IPC分类号: A61F2/00 , C12M1/22 , C12M1/24 , C12N11/02 , A61K38/06 , C08B15/06 , C07K14/78 , C08G63/91 , C08G18/83 , C08F20/18 , C08F112/08 , C08F283/02 , C08G79/02
CPC分类号: G01N33/543 , A61L27/227 , A61L27/34 , A61L27/54 , A61L31/047 , A61L31/10 , A61L31/16 , A61L2300/00 , A61L2300/80 , C07K5/1021 , C07K17/02 , G01N2333/78 , G01N2333/96433 , G01N2333/96486 , G01N2333/976
摘要: A substrate is provided having a biomolecule immobilised thereon, wherein the biomolecule is connected via an enzyme-cleavable link to a blocking moiety such that cleavage of the link causes removal of the blocking moiety and activation of the biomolecule.
摘要翻译: 提供了具有固定在其上的生物分子的底物,其中生物分子通过可酶切链接连接到阻断部分,使得链接的切割引起去除阻断部分并激活生物分子。