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1.
公开(公告)号:US20050131648A1
公开(公告)日:2005-06-16
申请号:US10760678
申请日:2004-01-20
申请人: Jonathan Derry , William Fanslow , William Dougall
发明人: Jonathan Derry , William Fanslow , William Dougall
CPC分类号: G01N33/6872 , C07K14/4702 , G01N2500/00 , G16B50/00
摘要: The present invention provides methods for identifying a molecule that antagonizes or agonizes CD40 activity by screening for molecules that modulate the binding of NEMO and CYLD. Also provided are assays useful in screening for the binding of NEMO and CYLD and databases and methods useful for analyzing the resultant information.
摘要翻译: 本发明提供了通过筛选调节NEMO和CYLD的结合的分子来鉴定拮抗或激动CD40活性的分子的方法。 还提供了可用于筛选NEMO和CYLD的结合的测定法和用于分析所得信息的数据库和方法。