公开(公告)号：US20190048077A1

公开(公告)日：2019-02-14

申请号：US16079927

申请日：2017-05-01

申请人： Jonathan Tsai ,  Nathaniel Fernhoff ,  Rahul Sinha ,  Yuval Rinkevich ,  Irving L. Weissman

发明人： Jonathan Tsai ,  Nathaniel Fernhoff ,  Rahul Sinha ,  Yuval Rinkevich ,  Irving L. Weissman

IPC分类号： C07K16/28 ,  A61K31/343 ,  A61K31/198 ,  A61K31/473 ,  A61K31/7004 ,  A61K38/05 ,  A61K38/16 ,  A61K38/17 ,  A61K49/00 ,  A61P41/00

摘要： Aspects of the present disclosure include methods of treating a subject to reduce adhesion formation, the method comprising administering to a subject in need of thereof an agent that that targets adhesion-formation by injured mesothelial cells. The agent can act at a variety of checkpoints in the development of adhesions by injured mesothelial cells, including: targeting the injured mesothelial cells for destruction, recruiting inflammatory macrophages to the site of adhesion, preventing neutrophil recruitment to the site of adhesion, and/or inhibiting the expression or activity of a gene product whose expression is induced in the injured mesothelial cells. Compositions and kits for performing the methods are also provided.

公开(公告)号：US20100198642A1

公开(公告)日：2010-08-05

申请号：US12614766

申请日：2009-11-09

申请人： Gautam Nadkarni ,  I. B. Madhukar ,  Himani Tewari ,  Elton Martin Barretto ,  Praveen Poornima Muraleedharan Nair ,  Rahul Sinha ,  S. Subramania Satish Kumar ,  Rohit Nand ,  Vishwanathan S.

发明人： Gautam Nadkarni ,  I. B. Madhukar ,  Himani Tewari ,  Elton Martin Barretto ,  Praveen Poornima Muraleedharan Nair ,  Rahul Sinha ,  S. Subramania Satish Kumar ,  Rohit Nand ,  Vishwanathan S.

IPC分类号： G06Q10/00

CPC分类号： G06Q10/0633 ,  G06Q10/06

摘要： The present invention provides a method, system and computer program product for managing one or more processes in an organization. The system enables a user to define various process clusters. The process clusters include various associated processes that are made compliant with a predefined set of standards. Further, the system integrates various process clusters and enables interaction among various processes. Furthermore, the system provides a common access to the process clusters and the associated processes.

摘要翻译： 本发明提供一种用于管理组织中的一个或多个进程的方法，系统和计算机程序产品。 该系统使用户能够定义各种进程集群。 过程集群包括符合预定义的一组标准的各种关联过程。 此外，该系统集成了各种流程集群，并实现了各种流程之间的交互。 此外，系统提供对进程集群和相关进程的公共访问。