公开(公告)号：US20100068315A1

公开(公告)日：2010-03-18

申请号：US12623341

申请日：2009-11-20

申请人： Jong Won LEE ,  Ki-Chul HWANG ,  Hyung Soo HAN ,  Sun Ha LIM ,  Hyeong-Kyu LEE ,  Sang Hyuk LEE ,  Kyu Won KIM ,  Hyung Oh JUN ,  Hyun Jeong KIM ,  In-Seon LEE ,  Chae Ha YANG

发明人： Jong Won LEE ,  Ki-Chul HWANG ,  Hyung Soo HAN ,  Sun Ha LIM ,  Hyeong-Kyu LEE ,  Sang Hyuk LEE ,  Kyu Won KIM ,  Hyung Oh JUN ,  Hyun Jeong KIM ,  In-Seon LEE ,  Chae Ha YANG

IPC分类号： A61K36/899 ,  A61P25/28

CPC分类号： A61K36/899 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/322 ,  A23V2250/21

摘要： The present invention relates to a composition comprising extracts of Gramineae plant that improves cell viability under hypoxic conditions by inhibiting apoptosis. Thus, the extract of Triticum aestivum L., one of the Gramineae plant, of the present invention, in particular, prevents damage of brain, heart and kidney in animal models of ischemic diseases, and it also improves memory in an animal model of Alzheimer's disease. Therefore, a composition comprising extracts of Gramineae can be used as therapeutic agents or health care foods for preventing and treating ischemic diseases and degenerative brain diseases.

摘要翻译： 本发明涉及包含通过抑制细胞凋亡在缺氧条件下改善细胞活力的禾本科植物提取物的组合物。 因此，特别地，本发明的禾本科植物之一的小麦Triticum aestivum L.的提取物防止脑，心脏和肾脏在缺血性疾病的动物模型中的损伤，并且还改善了阿尔茨海默病动物模型中的记忆 疾病。 因此，包含禾本科植物提取物的组合物可用作预防和治疗缺血性疾病和退行性脑疾病的治疗剂或保健食品。