公开(公告)号：US20050272749A1

公开(公告)日：2005-12-08

申请号：US10531981

申请日：2003-11-04

申请人： Jordi Tormo Blasco ,  Carsten Bletner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

发明人： Jordi Tormo Blasco ,  Carsten Bletner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

IPC分类号： C07D487/04 ,  A61K31/519

CPC分类号： C07D487/04

摘要： 5-Alkyl-7-aminotriazolopyrimidines of the formula I, where: R1, R2 are hydrogen, alkyl, alkenyl, alkynyl, haloalkyl, cycloalkyl, phenyl, naphthyl; 5- or 6-membered saturated, unsaturated or aromatic heterocyclyl which contains one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom; or R1 and R2 together with the bridging nitrogen atom can form a 5- or 6-membered ring which contains one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom; R3 is cycloalkyl or bicycloalkyl; where R1, R2 and R3 may be substituted as outlined in the description; X is alkyl or haloalkyl; and their salts; processes and intermediates for their preparation, compositions comprising them and their use for controlling phytopathogenic harmful fungi are described.

摘要翻译： 式I的5-烷基-7-氨基三唑并嘧啶，其中：R 1，R 2是氢，烷基，烯基，炔基，卤代烷基，环烷基，苯基，萘基; 含有1-4个氮原子或一至三个氮原子和一个硫或氧原子的5-或6-元饱和，不饱和或芳族杂环基; 或R 1和R 2与桥连氮原子一起可以形成含有1-4个氮原子或一至三个氮原子的5-或6-元环，并且 一个硫或氧原子; R 3是环烷基或双环烷基; 其中R 1，R 2和R 3可以如说明书中概述的那样被取代; X是烷基或卤代烷基; 和它们的盐; 描述了其制备方法和中间体，包含它们的组合物及其用于控制​​植物病原性有害真菌的用途。

公开(公告)号：US20050272748A1

公开(公告)日：2005-12-08

申请号：US10531980

申请日：2003-11-14

申请人： Jordi Tormo Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

发明人： Jordi Tormo Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

IPC分类号： A01N43/90 ,  C07D487/04 ,  A61K31/519

CPC分类号： C07D487/04 ,  A01N43/90

摘要： 2-Mercapto-substituted triazolopyrimidines of the formula I in which the substituents are as defined below: L is halogen, cyano, nitro, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, alkoxy, alkenyloxy, alkynyloxy, haloalkoxy or —C(═O)-A; A is hydrogen, hydroxyl, alkyl, alkenyl, alkoxy, haloalkoxy, alkylamino or dialkylamino; m is 0, 1, 2, 3, 4 or 5; X is halogen, cyano, alkyl, haloalkyl, alkoxy or haloalkoxy; R1, R2 are hydrogen, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, alkadienyl, haloalkenyl, cycloalkenyl, alkynyl, haloalkynyl or cycloalkynyl, phenyl, naphthyl or a five- to ten-membered saturated, partially unsaturated or aromatic heterocycle which contains one to four hetero atoms from the group consisting of O, N and S; R1 and R2 together with the nitrogen atom to which they are attached may also form a five- or six-membered ring which may be interrupted by an atom from the group consisting of O, N and S; where R1 and/or R2 may be substituted as stated in the description; processes for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic harmful fungi are described.

摘要翻译： 2-巯基取代的式Ⅰ的三唑并嘧啶，其中取代基如下：L是卤素，氰基，硝基，烷基，烯基，炔基，卤代烷基，卤代烯基，烷氧基，烯氧基，炔氧基，卤代烷氧基或-C ）-一个; A是氢，羟基，烷基，烯基，烷氧基，卤代烷氧基，烷基氨基或二烷基氨基; m为0,1,2,3,4或5; X是卤素，氰基，烷基，卤代烷基，烷氧基或卤代烷氧基; R 1，R 2是氢，烷基，卤代烷基，环烷基，卤代环烷基，烯基，链二烯基，卤代烯基，环烯基，炔基，卤代炔基或环炔基，苯基，萘基或五 至10元饱和，部分不饱和或芳族杂环，其含有一个至四个由O，N和S组成的组的杂原子; R 1和R 2与它们所连接的氮原子一起也可以形成五元或六元环，其可被来自基团的原子中断 由O，N和S组成; 其中R 1和/或R 2可以如描述中所述被取代; 描述了制备这些化合物的方法，包含它们的组合物及其用于控制​​植物病原性有害真菌的用途。

公开(公告)号：US20060241128A1

公开(公告)日：2006-10-26

申请号：US10532719

申请日：2003-11-04

申请人： Jordi Tormo I Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

发明人： Jordi Tormo I Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

IPC分类号： A01N43/90 ,  C07D487/04

CPC分类号： C07C69/65 ,  A01N43/90 ,  C07D487/04

摘要： Substituted 6-(2-halogenphenyl)-triazolopyrimidines of formula I in which R1 denote alkyl, alkenyl, alkynyl, alkadienyl, haloalkyl, haloalkenyl, cycloalkyl, phenyl, naphthyl, or a 5- or 6-membered saturated, unsaturated, or aromatic heterocycle, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, wherein R1 and R2 radicals may be substituted as defined in the description, R2 denote hydrogen, or a group mentioned for R1; or R1 and R2 together with the interjacent nitrogen atom represent a 5- or 6-membered heterocycle, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, which ring may be substituted as defined in the description; Hal is halogen; L1, L3 independently denote hydrogen, halogen, or alkyl; L2 is hydrogen, halogen, haloalkyl, or NH2, NHRb, or N(Rb)2, wherein Rb is as defined in the description, wherein at least one from L1, L2, and L3 is not hydrogen; X is halogen, cyano, alkyl, alkoxy, haloalkoxy or alkenyloxy. processes for their preparation, compositions containing them and to their use for combating phytopathogenic fungi.

摘要翻译： 其中R 1表示烷基，烯基，炔基，链二烯基，卤代烷基，卤代烯基，环烷基，苯基，萘基或5-或6-元的取代的6-（2-卤代苯基） - 三唑并嘧啶， 含有1至4个氮原子或1至3个氮原子和1个硫或氧原子的饱和，不饱和或芳族杂环，其中R 1和R 2可以是 如说明书中所定义，R 2表示氢或R 1所提及的基团; 或R 1和R 2连同中间的氮原子代表含有1-4个氮原子或一至三个氮原子的一个或多个六元杂环，一个 硫或氧原子，该环可以如说明书中所定义取代; 卤素是卤素; L 1，L 3独立地表示氢，卤素或烷基; L 2是氢，卤素，卤代烷基或NH 2，NHR b或/或N（R b） 其中R b如描述中所定义，其中至少一个L 1，L 2， ，而L 3不是氢; X是卤素，氰基，烷基，烷氧基，卤代烷氧基或烯氧基。 其制备方法，含有它们的组合物及其用于对抗植物病原真菌的用途。

公开(公告)号：US20060079537A1

公开(公告)日：2006-04-13

申请号：US10531898

申请日：2003-11-14

申请人： Jordi Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

发明人： Jordi Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

IPC分类号： A61K31/519 ,  C07D487/04

CPC分类号： C07D487/04 ,  A01N43/90

摘要： 2-Substituted triazolopyrimidines of the formula I, in which the substituents are as defined below: L are halogen, cyano, nitro, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, alkoxy, alkenyloxy, alkynyloxy, haloalkoxy, —C(═O)-A or S(═O)pA′; A and A′ are as defined in the description; p is 0, 1 or 2; m is 0, 1, 2, 3, 4 or 5; X is cyano, alkyl, haloalkyl, alkoxy or haloalkoxy; R1,R2 are hydrogen, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, alkadienyl, haloalkenyl, cycloalkenyl, alkynyl, haloalkynyl or cycloalkynyl, phenyl, naphthyl or a five- to ten-membered saturated, partially unsaturated or aromatic heterocycle which contains one to four heteroatoms from the group consisting of O, N and S, R1 and R2 together with the nitrogen atom to which they are attached may also form a five- or six-membered ring which may be interrupted by an atom from the group consisting of O, N and S, where R1 and/or R2 may be substituted as defined in the description; and R3 is cyano, hydroxyl, alkoxy, alkenyloxy, haloalkoxy, haloalkenyloxy, NR1R2 or S(O)nR31, where n and R31 are as defined in the description; Processes and intermediates for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic harmful fungi are described.

摘要翻译： 氰基，硝基，烷基，烯基，炔基，卤代烷基，卤代烯基，烷氧基，烯氧基，炔氧基，卤代烷氧基，-C（ - O） - 取代的取代基如下： -A或S（-O） A'; A和A'如说明书所定义; p为0,1或2; m为0,1,2,3,4或5; X是氰基，烷基，卤代烷基，烷氧基或卤代烷氧基; R 1，R 2是氢，烷基，卤代烷基，环烷基，卤代环烷基，烯基，链二烯基，卤代烯基，环烯基，炔基，卤代炔基或环炔基，苯基，萘基或五 - 至十元饱和的，部分不饱和的或芳族杂环，其含有一至四个由O，N和S组成的组的杂原子，R 1和R 2连同 它们所连接的氮原子也可以形成可被来自O，N和S的原子间隔的五元或六元环，其中R 1和/或 R 2可以如说明书中定义的取代; 和R 3是氰基，羟基，烷氧基，烯氧基，卤代烷氧基，卤代烯氧基，NR 1 R 2或S（O）n 其中n和R 31如在说明书中所定义的; 描述了制备这些化合物的方法和中间体，包含它们的组合物及其用于控制​​植物病原性有害真菌的用途。

公开(公告)号：US20060199801A1

公开(公告)日：2006-09-07

申请号：US10551810

申请日：2004-04-16

申请人： Jordi i Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Oliver Wagner ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Maria Scherer ,  Reinhard Stierl

发明人： Jordi i Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Oliver Wagner ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Maria Scherer ,  Reinhard Stierl

IPC分类号： A61K31/551 ,  A61K31/541 ,  A61K31/53 ,  A61K31/519

CPC分类号： C07D487/04 ,  A01N43/90

摘要： Bicyclic compounds of the formula I in which A1 or A5 is C and the other of the two variables A1, A5 is N, C or C—R3; A2, A3, A4 independently of one another are N or C—R3a, where one of the variables A2, A3 or A4 may also be S or a group N—R4 if A1 and A5 are both C, and where A4 is not N or C—R3a if A1 is N, A3 is C—R3a and A5 is C, and where A1 is attached to A2 and A3 to A4 or A2 is attached to A3 and A4 to A5 or A1 is attached to A5 and A2 to A3 or A1 is attached to A5 and A3 to A4 or A1 is attached to A2 and A4 to A5 by double bonds; n is 0, 1, 2, 3, 4 or 5; Ra is halogen, cyano, C1-C6-alkyl, C1-C6-alkoxy, C1-C6-haloalkyl, C1-C6-haloalkoxy, C2-C6-alkenyl, C2-C6-alkenyloxy or C(O)R5; R1 is halogen, cyano, C1-C10-alkyl, where a carbon atom of the C1-C10-alkyl radical may be replaced by a silicium atom, C1-C6-haloalkyl, C2-C10-alkenyl, C2-C6-haloalkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, C3-C8-cycloalkyl-C1-C4-alkyl, where the cycloalkyl moiety of the two last-mentioned groups may be unsubstituted or contain 1, 2, 3, 4, 5, or 6 radicals selected from the group consisting of C1-C4-alkylidene, C1-C4-alkyl, halogen, C1-C4-haloalkyl and hydroxy and the alkyl moiety of C3-C8-cycloalkyl-C1-C4-alkyl may be unsubstituted or contain 1, 2, 3, or 4 radicals selected from the group consisting of halogen, C1-C4-haloalkyl and hydroxy, C5-C8-cycloalkenyl which may be unsubstituted or contain 1, 2, 3 or 4 radicals selected from the group consisting of C1-C4-alkyl, halogen, C1-C4-haloalkyl and hydroxy, OR6, SR6, NR7R8, a radical of the formula —C(R11)(R12)C(═NOR13)(R14) or a radical of the formula —C(═NOR15)C(═NOR16)(R17); R2 is halogen, cyano, C1-C6-alkyl, C1-C6-haloalkyl, C2-C6-alkenyl, C2-C6-haloalkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, C5-C8-cycloalkenyl, OR6, SR6 or NR7R8; and the agriculturally acceptable salts of the compounds I, crop protection compositions comprising at least one compound of the formula I and/or an agriculturally acceptable salt of I and at least one solid or liquid carrier and a method for controlling phytopathogenic harmful fungi are described.

公开(公告)号：US20060167017A1

公开(公告)日：2006-07-27

申请号：US10539039

申请日：2003-12-16

申请人： Bernd Muller ,  Jordi Blasco ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Wassilios Grammenos ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

发明人： Bernd Muller ,  Jordi Blasco ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Wassilios Grammenos ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

IPC分类号： C07D487/04 ,  A01N43/90

CPC分类号： C07D487/04

摘要： Triazolopyrimidines of the formula I where the index and the substituents are as defined below: R1 is C1-C10-alkyl, C2-C10-alkenyl, C2-C10-alkynyl, C3-C10-cycloalkyl, C3-C10-cycloalkenyl, phenyl, naphthyl, or a five- to ten-membered saturated, partially unsaturated or aromatic heterocycle which is attached via carbon to the triazolopyrimidine and contains one to four heteroatoms from the group consisting of N, O and S; R2 is C1-C4-alkyl which may be substituted by halogen, cyano, nitro or C1-C2-alkoxy; n is 0 or an integer from 1 to 4; R is as defined in the description; X is SOm—Rx, NRxRy or NRx—(C═O)—Ry; m is 0 or an integer from 1 to 3; and processes for preparing these compounds, compositions comprising them and their use for controlling harmful fungi are described.

摘要翻译： 其中指数和取代基如下定义的式I的三唑并嘧啶：R 1是C 1 -C 10 - 烷基， C 1 -C 10亚烷基，C 2 -C 10 - 炔基，C 3 - 亚烷基 C 1 -C 10 - 环烷基，C 3 -C 10 - 环烯基，苯基，萘基或五至十元饱和的， 部分不饱和或芳族杂环，其通过碳连接到三唑并嘧啶并且包含一至四个由N，O和S组成的组的杂原子; R 2是可以被卤素，氰基，硝基或C 1 H 3取代的C 1 -C 4 - 烷基 -C 2 - 烷氧基; n为0或1至4的整数; R如说明书所定义; X是SO x，x，x，x，y，x，y，x， - （CO）-R y; m为0或1〜3的整数; 并描述了制备这些化合物的方法，包含它们的组合物及其用于控制​​有害真菌的用途。

公开(公告)号：US20050176736A1

公开(公告)日：2005-08-11

申请号：US10508409

申请日：2003-03-19

申请人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl ,  Ulrich Schofl

发明人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl ,  Ulrich Schofl

IPC分类号： A01N43/90 ,  C07C255/57 ,  C07D487/04 ,  A61K31/519

CPC分类号： C07D487/04 ,  A01N43/90 ,  C07C255/57

摘要： The invention relates to triazolopyrimidines of formula (I), in which the substituents are defined as follows: L1 represents cyano, S(═O)nA1 or C(═O)A2, wherein A1 stands for hydrogen, hydroxy, alkyl, alkylamino or dialkylamino; A2 stands for C1-C8 alkoxy, C1-C6 haloalkoxy or one of the groups named in A1; and n stands for 0, 1 or 2; L2, L3 represent hydrogen or halogen; L4, L5 represent hydrogen, halogen or alkyl; X represents halogen, cyano, alkyl, haloalkyl, alkoxy or haloalkoxy; R1 represents alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, alkadienyl, haloalkenyl, cycloalkenyl, alkynyl, haloalkynyl or cycloalkynyl, phenyl, naphthyl, or a five to ten-membered saturated, partially unsaturated or aromatic heterocyclus containing between one and four heteroatoms from the group containing O, N or S; R2 represents hydrogen or R1; R1 and R2 can form, together with the nitrogen atom to which they are bonded, a five or six-membered ring, which can be interrupted and/or substituted by an atom from the group O, N and S; whereby R1 and/or R2 can be substituted in accordance with the description. The invention also relates to methods and intermediate products for producing said compounds, to agents containing the latter and to the use of said compounds for combating harmful fungi.

摘要翻译： 本发明涉及式（I）的三唑并嘧啶，其中取代基定义如下：L 1表示氰基，S（-O）n A 1 或其中A 1代表氢，羟基，烷基，烷基氨基或二烷基氨基;或C（= O） A 2代表C 1 -C 8烷氧基，C 1 -C 6烷基，C 1 -C 6 - >卤代烷氧基或在A 中命名的基团之一; 而n代表0,1或2; L 2，L 3表示氢或卤素; L 4，L 5代表氢，卤素或烷基; X表示卤素，氰基，烷基，卤代烷基，烷氧基或卤代烷氧基; R 1表示烷基，卤代烷基，环烷基，卤代环烷基，烯基，链烯基，卤代烯基，环烯基，炔基，卤代炔基或环炔基，苯基，萘基或五至十元饱和，部分不饱和或芳族杂环 含有一个至四个来自含有O，N或S的基团的杂原子; R 2表示氢或R 1; R 1和R 2可以与它们所键合的氮原子一起形成五元或六元环，其可被中断和/或被 来自O，N和S族的原子; 其中R 1和/或R 2可以根据描述被取代。 本发明还涉及用于生产所述化合物的方法和中间产物，含有后者的试剂和所述化合物用于防治有害真菌的用途。

公开(公告)号：US20070054929A1

公开(公告)日：2007-03-08

申请号：US10555894

申请日：2004-05-10

申请人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Oliver Wagner ,  Siegfried Strathmann ,  Ulrich Schofl ,  Maria Scherer ,  Reinhard Stierl

发明人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Oliver Wagner ,  Siegfried Strathmann ,  Ulrich Schofl ,  Maria Scherer ,  Reinhard Stierl

IPC分类号： A61K31/506 ,  C07D403/04

CPC分类号： C07D239/48 ,  A01N43/56 ,  C07D403/04

摘要： The present invention relates to pyrimidines of the formula I in which the index n and the substituents L, R1-R3 are as defined in the description and R4 corresponds to one of the formulae and to processes and intermediates for preparing these compounds, to compositions comprising them and to their use for controlling phytopathogenic harmful fungi.

摘要翻译： 本发明涉及式I的嘧啶，其中指数n和取代基L，R 1〜R 3如说明书中所定义， 4对应于一个公式，以及制备这些化合物的方法和中间体，包含它们的组合物及其用于控制​​植物病原性有害真菌的用途。

公开(公告)号：US20060258685A1

公开(公告)日：2006-11-16

申请号：US10558251

申请日：2004-05-27

申请人： Olivier Wagner ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Wassilios Grammenos ,  Andreas Gypser ,  Bernd Muller ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Jordi Blasco ,  Alan Akers ,  John-Bryan Speakman ,  Michael Rack ,  Reinhard Stierl ,  Maria Scherer ,  Ulrich Schofl ,  Siegfried Strathmann

发明人： Olivier Wagner ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Wassilios Grammenos ,  Andreas Gypser ,  Bernd Muller ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Jordi Blasco ,  Alan Akers ,  John-Bryan Speakman ,  Michael Rack ,  Reinhard Stierl ,  Maria Scherer ,  Ulrich Schofl ,  Siegfried Strathmann

IPC分类号： A61K31/519 ,  C07D487/04

CPC分类号： C07D487/04 ,  A01N43/90

摘要： The invention relates to substituted pyrazolopyrimidines of formula (I) wherein the substituents have the following designations: L represents halogen, alkyl, halogenalkyl, alkenyl, alkoxy, amino, NHR, NR2, cyano, S(═O)nA1 or C(═O)A2, R representing alkyl or alkylcarbonyl, A1 representing hydrogen, hydroxy, alkyl, alkylamino or dialkylamino, n representing 0, 1 or 2, and A2 representing alkenyl, alkoxy, halogenalkoxy or one of the groups cited for A1; m represents 0 or 1 to 5; R1 represents alkyl, halogenalkyl, cycloalkyl, halogencycloalkyl, alkenyl, alkadienyl, halogenalkenyl, cycloalkenyl, alkinyl, halogenalkinyl or cycloalkinyl, phenyl, naphthyl, or a five-membered to ten-membered saturated, partially unsaturated or aromatic heterocycle containing between one and four heteroatoms from the group O, N or S; and R2 represents hydrogen or one of the groups cited for R1. Together with the nitrogen atom to which they are bonded, R1 and R2 can form a five-membered to six-membered ring that can be interrupted by an atom from the groups O, N and S, and R1 and/or R2 can also be substituted according to the description. Furthermore, in formula (I): X represents halogen, cyano, OH, alkyl, alkoxy or halogenalkoxy; Y represents a five-membered to ten-membered saturated, partially unsaturated or aromatic heterocycle according to the description, or a group X or another group according to the description; p represents 1 or 2, the groups Y being potentially different when p=2; and p represents 0, when X is according to the description. The invention also relates to methods and intermediate products for producing said compounds, agents containing the same, and the use thereof for controlling phytopathogenic fungi.

公开(公告)号：US20060058326A1

公开(公告)日：2006-03-16

申请号：US10541386

申请日：2004-01-28

申请人： Bernd Muller ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Wassilios Grammenos ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Jordi Tormo I Blasco ,  Oliver Wagner ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

发明人： Bernd Muller ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Wassilios Grammenos ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Jordi Tormo I Blasco ,  Oliver Wagner ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

IPC分类号： A61K31/513

CPC分类号： C07D239/56 ,  A01N43/54 ,  A01N43/56 ,  A01N43/58 ,  A01N43/60 ,  A01N43/653 ,  A01N43/707 ,  A01N43/78 ,  A01N43/82 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D403/04

摘要： Pyrimidines of the formula I in which Ln is as defined in the description and the substituents R1, R2 and R3 are as defined below: R1 is C1-C10-alkyl, C2-C10-alkenyl, C2-C10-alkynyl, C3-C12-cycloalkyl, C3-C10-cycloalkenyl, phenyl or a five- to ten-membered saturated, partially unsaturated or aromatic heterocycle which is attached via carbon and contains one to four heteroatoms from the group consisting of O, N and S; R2 is halogen, cyano, C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkynyl, C1-C4-alkoxy, C3-C4-alkenyloxy or C3-C4-alkynyloxy, where the alkyl, alkenyl and alkynyl radicals of R2 may be substituted by halogen, cyano, nitro, C1-C2-alkoxy or C1-C4-alkoxycarbonyl; R3 is a five- or six-membered saturated, partially unsaturated or aromatic mono- or bicyclic heterocycle which contains one to four heteroatoms from the group consisting of O, N and S; and processes and intermediates for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic harmful fungi are described.

摘要翻译： 式I的嘧啶