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    Antiseptic based on bispyridinium alkanes
    4.
    发明授权
    Antiseptic based on bispyridinium alkanes 有权
    基于双吡啶烷烃的防腐剂

    公开(公告)号：US08541454B2

    公开(公告)日：2013-09-24

    申请号：US13156635

    申请日：2011-06-09

    申请人： Sabine Behrends ,  Andreas Dettmann ,  Mona Golombiewski ,  Elke Kassens

    发明人： Sabine Behrends ,  Andreas Dettmann ,  Mona Golombiewski ,  Elke Kassens

    IPC分类号： A01N43/40 ,  A61K31/4425

    CPC分类号： A61K9/0014 ,  A01N43/40 ,  A61K31/4425 ,  A61K47/10 ,  A01N2300/00 ,  A01N25/12

    摘要： An antimicrobially effective composition includes a) at least 0.15% by weight of bispyridinium alkane, b) at least 3.5% by weight of humectant and c) water. Upon dilution with water, the composition produces a solution with an osmolality of from 230 to 350 mOsmol/kg and is free from surfactant. It is used as an antiseptic and is suitable for use in a method for the disinfection of injured or uninjured skin of a human being or animal, preference being given to use in the case of newborns, in particular those born prematurely.

    摘要翻译： 抗微生物组合物包括a）至少0.15重量％的双吡啶烷烃，b）至少3.5重量％的湿润剂和c）水。 用水稀释后，组合物产生的重量摩尔渗透压浓度为230至350mOsmol / kg，不含表面活性剂。 它用作防腐剂，并且适用于消毒人或动物的受伤或未受伤皮肤的方法，优选在新生儿的情况下使用，特别是过早出生的那些。

    STABILIZED, ANTIMICROBIALLY EFFECTIVE COMPOSITION WITH A CONTENT OF BISPYRIDINIUM ALKANE
    5.
    发明申请
    STABILIZED, ANTIMICROBIALLY EFFECTIVE COMPOSITION WITH A CONTENT OF BISPYRIDINIUM ALKANE 有权
    具稳定性，具有双嘧丝巴碱含量的抗微生物有效成分

    公开(公告)号：US20110003857A1

    公开(公告)日：2011-01-06

    申请号：US12919523

    申请日：2009-02-18

    申请人： Wolfgang Beilfuss ,  Andreas Dettmann ,  Sabine Behrends ,  Mona Golombiewski ,  Thomas Spuida ,  Elke Kassens

    发明人： Wolfgang Beilfuss ,  Andreas Dettmann ,  Sabine Behrends ,  Mona Golombiewski ,  Thomas Spuida ,  Elke Kassens

    IPC分类号： A61K31/444 ,  A61P31/04

    CPC分类号： A61K31/4425 ,  A01N43/40 ,  A61K8/4926 ,  A61Q11/00 ,  A61Q17/005 ,  A01N25/22 ,  A01N25/30 ,  A01N2300/00

    摘要： An aqueous-based composition which includes a) at least one bispyridinium alkane (for example octenidine) and b) at least one stabilizer selected from antioxidants, complexing agents, reducing agents, UV filters and photoprotective agents, in particular α-tocopherol, and BHT. The composition can also include c) one or more auxiliaries selected from, for example, nonionic surfactants, ethers, solvents and polymers, in particular fatty alcohol alkoxylates and alkoxylated fatty acid monoglycerides. The presence of the stabilizer reduces or prevents the appearance of decomposition products of bispyridinium alkanes and, in the case of the presence of auxiliaries, of decomposition products of the auxiliaries, such as ethers and peroxides.

    摘要翻译： 一种水基组合物，其包含a）至少一种双吡啶烷烃（例如，辛烯尼酸）和b）至少一种稳定剂，其选自抗氧化剂，络合剂，还原剂，UV过滤剂和光保护剂，特别是α-生育酚和BHT 。 组合物还可以包括c）一种或多种选自例如非离子表面活性剂，醚，溶剂和聚合物，特别是脂肪醇烷氧基化物和烷氧基化脂肪酸单甘油酯的助剂。 稳定剂的存在降低或防止双吡啶烷烃的分解产物的出现，以及在助剂的存在的情况下，助剂如醚和过氧化物的分解产物的出现。

    Stabilized, antimicrobially effective composition with a content of bispyridinium alkane
    6.
    发明授权
    Stabilized, antimicrobially effective composition with a content of bispyridinium alkane 有权
    具有双吡啶烷烃含量的稳定的抗微生物组合物

    公开(公告)号：US08609697B2

    公开(公告)日：2013-12-17

    申请号：US12919523

    申请日：2009-02-18

    申请人： Wolfgang Beilfuss ,  Andreas Dettmann ,  Sabine Behrends ,  Mona Golombiewski ,  Thomas Spuida ,  Elke Kassens

    发明人： Wolfgang Beilfuss ,  Andreas Dettmann ,  Sabine Behrends ,  Mona Golombiewski ,  Thomas Spuida ,  Elke Kassens

    IPC分类号： A01N43/40 ,  A61K31/4425

    CPC分类号： A61K31/4425 ,  A01N43/40 ,  A61K8/4926 ,  A61Q11/00 ,  A61Q17/005 ,  A01N25/22 ,  A01N25/30 ,  A01N2300/00

    摘要： An aqueous-based composition which includes a) at least one bispyridinium alkane (for example octenidine) and b) at least one stabilizer selected from antioxidants, complexing agents, reducing agents, UV filters and photoprotective agents, in particular α-tocopherol, and BHT. The composition can also include c) one or more auxiliaries selected from, for example, nonionic surfactants, ethers, solvents and polymers, in particular fatty alcohol alkoxylates and alkoxylated fatty acid monoglycerides. The presence of the stabilizer reduces or prevents the appearance of decomposition products of bispyridinium alkanes and, in the case of the presence of auxiliaries, of decomposition products of the auxiliaries, such as ethers and peroxides.

    摘要翻译： 一种水基组合物，其包含a）至少一种双吡啶烷烃（例如，辛烯尼酸）和b）至少一种选自抗氧化剂，络合剂，还原剂，UV过滤剂和光保护剂，特别是α-生育酚和BHT的稳定剂 。 组合物还可以包括c）一种或多种选自例如非离子表面活性剂，醚，溶剂和聚合物，特别是脂肪醇烷氧基化物和烷氧基化脂肪酸单甘油酯的助剂。 稳定剂的存在降低或防止双吡啶烷烃的分解产物的出现，以及在助剂的存在的情况下，助剂如醚和过氧化物的分解产物的出现。

    Tuberculocidal disinfectant
    10.
    发明授权
    Tuberculocidal disinfectant 失效
    结核消毒剂

    公开(公告)号：US06376547B1

    公开(公告)日：2002-04-23

    申请号：US09231632

    申请日：1999-01-15

    申请人： Sabine Behrends ,  Andreas Dettmann ,  Michael Mohr

    发明人： Sabine Behrends ,  Andreas Dettmann ,  Michael Mohr

    IPC分类号： A61K3100

    CPC分类号： A01N37/44 ,  A01N47/44 ,  A01N33/12 ,  A01N39/00 ,  A01N25/30 ,  A01N2300/00

    摘要： The invention relates to the use of an N,N′-substituted glycine or of an N,N′-substituted derivative of glycine (a) of the general formula I in which R1 is hydrogen or a straight-chain or branched, saturated or unsaturated alkyl, alkaryl or aralkyl radical having 1 to 30 C atoms, which can optionally contain heteroatoms such as O, S and N, R2 is a straight-chain or branched, saturated or unsaturated alkyl, alkaryl or aralkyl radical having 1 to 30 C atoms containing at least one primary, secondary or tertiary amino group and X is OH, OR3, NH2, NHR4, NR4R5 or O−M+, where R3, R4 and R5 are straight-chain or branched, saturated or unsaturated alkyl, alkaryl or aralkyl radicals which can be identical to or different from one another, and M is a metal cation, as active compound in a tuberculocidal disinfectant.

    摘要翻译： 本发明涉及使用N，N'-取代的甘氨酸或N，N-取代的甘氨酸衍生物（a），其通式为Iin，其中R 1为氢或直链或支链，饱和或不饱和的 具有1至30个C原子的烷基，烷芳基或芳烷基，其可以任选地含有杂原子如O，S和N，R 2是具有1至30个C原子的直链或支链，饱和或不饱和的烷基，烷芳基或芳烷基 含有至少一个伯，仲或叔氨基，X是OH，OR 3，NH 2，NHR 4，NR 4 R 5或O-M +，其中R 3，R 4和R 5是直链或支链，饱和或不饱和的烷基，烷芳基或芳烷基 其可以相同或不同，M是金属阳离子，作为结核消毒剂中的活性化合物。