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    Adjuvants for rectal delivery of drug
    7.
    发明授权
    Adjuvants for rectal delivery of drug 失效
    佐剂用于直肠给药

    公开(公告)号：US4425337A

    公开(公告)日：1984-01-10

    申请号：US335498

    申请日：1981-12-30

    申请人： Jose Alexander ,  Joseph A. Fix

    发明人： Jose Alexander ,  Joseph A. Fix

    IPC分类号： A61K9/02 ,  A61K31/54 ,  A61K47/22

    CPC分类号： A61K47/22 ,  A61K31/54 ,  A61K9/02 ,  Y10S514/946

    摘要： A method and drug form enhancing the rate of absorption of a rectally administered drug from the rectal compartment into the blood stream of a warm blooded animal. The method includes the steps of preparing a drug form capable of being rectally administered. The drug form comprises a therapeutically effective unit dosage amount of a selected drug of the type which is capable of being absorbed into the blood stream from the rectal compartment and phenothiazines or salts thereof being present in the drug form in a sufficient amount to be effective in enhancing the drug absorption rate, when rectally administering the drug form to warm blooded animals.

    摘要翻译： 一种提高直肠给药的药物从直肠隔室吸入温血动物血液的方法和药物形式。 该方法包括制备能够被直肠给药的药物形式的步骤。 药物形式包括治疗有效的单位剂量的所选择的能够被吸收到来自直肠隔室的血液中的药物，吩噻嗪或其盐以足够的量存在于药物形式中 当将该药物形式直接给予温血动物时，提高药物吸收率。