公开(公告)号：US4661610A

公开(公告)日：1987-04-28

申请号：US887940

申请日：1986-07-22

申请人： Josef Muller ,  Walter-Wielant Wiersdorff ,  Wolfram Burst ,  Heinz Dralle ,  Ernst Schaffner ,  Rolf Steinkamp

发明人： Josef Muller ,  Walter-Wielant Wiersdorff ,  Wolfram Burst ,  Heinz Dralle ,  Ernst Schaffner ,  Rolf Steinkamp

IPC分类号： C07C255/53 ,  C07C120/04

CPC分类号： C07C255/00

摘要： Veratryl cyanide is prepared by chloromethylating veratrol in solution in toluene and then reacting the resulting veratryl chloride with from 1 to 5 moles of an alkali metal cyanide, by a process in which the toluene from the chloromethylation is not removed for the reaction with cyanide, and from 3 to 25% by weight, based on veratryl chloride, of water, from 5 to 50% by weight, based on toluene, of a ketone of 3 to 6 carbon atoms and from 0.1 to 10% by weight, based on veratryl chloride, of a phase transfer catalyst are added before the reaction with cyanide.

摘要翻译： 通过在甲苯溶液中氯甲基化藜芦醇，然后使得到的藜芦酰与1至5摩尔碱金属氰化物反应，其中氯甲基化的甲苯未被除去以与氰化物反应， 3至25重量％，基于藜芦醚，水，5至50重量％，基于甲苯，3至6个碳原子的酮和0.1至10重量％，基于藜芦 的相转移催化剂在与氰化物反应之前加入。