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![4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE](/abs-image/US/2014/09/11/US20140256784A1/abs.jpg.150x150.jpg)
1.发明申请4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE 有权4H-THIENO [3,2-C]基于琥珀酸的抑制剂及其使用方法公开(公告)号：US20140256784A1
公开(公告)日：2014-09-11
申请号：US14284106
申请日：2014-05-21
申请人： Joseph BARBOSA , Kenneth Gordon CARSON , Michael Walter GARDYAN , Jason Patrick HEALY , Qiang HAN , Ross MABON , Praveen PABBA , James TARVER, JR. , Kristen M. TERRANOVA , Ashok TUNOORI , Xiaolian XU
发明人： Joseph BARBOSA , Kenneth Gordon CARSON , Michael Walter GARDYAN , Jason Patrick HEALY , Qiang HAN , Ross MABON , Praveen PABBA , James TARVER, JR. , Kristen M. TERRANOVA , Ashok TUNOORI , Xiaolian XU
IPC分类号： C07D495/04
CPC分类号： C07D495/04 , C07D333/52
摘要： Compounds that may be used to inhibit Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting bone.
摘要翻译： 本发明描述了可用于抑制Notum果胶乙酰酯酶的化合物，以及包含它们的组合物及其用于治疗影响骨骼的疾病和障碍的方法。
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![4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE](/abs-image/US/2012/11/29/US20120302562A1/abs.jpg.150x150.jpg)
2.发明申请4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE 审中-公开4H-THIENO [3,2-C]基于琥珀酸的抑制剂及其使用方法公开(公告)号：US20120302562A1
公开(公告)日：2012-11-29
申请号：US13478529
申请日：2012-05-23
申请人： Joseph BARBOSA , Kenneth Gordon CARSON , Michael Walter GARDYAN , Jason Patrick HEALY , Qiang HAN , Ross MABON , Praveen PABBA , James TARVER, JR. , Kristen M. TERRANOVA , Ashok TUNOORI , Xiaolian XU
发明人： Joseph BARBOSA , Kenneth Gordon CARSON , Michael Walter GARDYAN , Jason Patrick HEALY , Qiang HAN , Ross MABON , Praveen PABBA , James TARVER, JR. , Kristen M. TERRANOVA , Ashok TUNOORI , Xiaolian XU
IPC分类号： A61K31/381 , C07D333/74 , A61K31/382 , C07D413/12 , A61K31/5377 , A61P19/10 , A61K31/41 , A61K31/4178 , A61K31/422 , A61K31/4535 , A61K31/4025 , A61K31/4436 , C07D495/04 , C07D409/12
CPC分类号： C07D495/04 , C07D333/52
摘要： Compounds that may be used to inhibit Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting bone.
摘要翻译： 本发明描述了可用于抑制Notum果胶乙酰酯酶的化合物，以及包含它们的组合物及其用于治疗影响骨骼的疾病和障碍的方法。
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3.发明申请公开(公告)号：US20120329818A1
公开(公告)日：2012-12-27
申请号：US13486122
申请日：2012-06-01
申请人： Hugh Alfred BURGOON , Nicole Cathleen GOODWIN , Bryce Alden HARRISON , Jason Patrick HEALY , Ying LIU , Ross MABON , Brett MARINELLI , David Brent RAWLINS , Dennis Stewart RICE , Norris Andrew WHITLOCK
发明人： Hugh Alfred BURGOON , Nicole Cathleen GOODWIN , Bryce Alden HARRISON , Jason Patrick HEALY , Ying LIU , Ross MABON , Brett MARINELLI , David Brent RAWLINS , Dennis Stewart RICE , Norris Andrew WHITLOCK
CPC分类号： C07D487/04
摘要： Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use. Particular compounds are of the formula:
摘要翻译： 公开了LIM激酶2的抑制剂，以及包含它们的药物组合物及其使用方法。 具体化合物具有下式：
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