公开(公告)号：US20050163290A1

公开(公告)日：2005-07-28

申请号：US11088360

申请日：2005-03-24

申请人： Timothy Gilles ,  Joseph Rogers ,  Richard Dishman

发明人： Timothy Gilles ,  Joseph Rogers ,  Richard Dishman

IPC分类号： G06Q30/06 ,  H04M3/22 ,  H04M3/51 ,  H04M11/00

CPC分类号： G06Q30/06 ,  G06Q30/0603 ,  H04M3/2254 ,  H04M3/51

摘要： A system and method for exchanging telecommunication service information between a telecommunication service provider and a telecommunication service customer include electronically receiving a request in a predefined format to establish an interactive session with a telecommunications customer, determining whether the telecommunications customer is authorized for electronically exchanging information and continuing only if the customer is authorized, parsing the request to identify information related to at least one telecommunications service offered by the telecommunications services provider, the telecommunications service having an associated identification code, determining whether the requested telecommunication service is available in a particular location, and automatically generating information associated with the requested telecommunications service and transmitting the information using the predetermined format to the customer. In one embodiment, the predetermined format is determined by a standards organization, such as ANSI, and transmitted during an interactive session using a TCP/IP connection.

公开(公告)号：US5192753A

公开(公告)日：1993-03-09

申请号：US689499

申请日：1991-04-23

申请人： Patrick L. McGeer ,  Joseph Rogers ,  John Sibley ,  Edith McGeer

发明人： Patrick L. McGeer ,  Joseph Rogers ,  John Sibley ,  Edith McGeer

IPC分类号： A61K45/00 ,  A61K31/00 ,  A61K31/19 ,  A61K31/195 ,  A61K31/235 ,  A61K31/38 ,  A61K31/40 ,  A61K31/405 ,  A61K31/415 ,  A61K31/42 ,  A61K31/425 ,  A61K31/44 ,  A61K31/54 ,  A61K31/60 ,  A61P25/28 ,  A61P29/00

CPC分类号： A61K31/621 ,  A61K31/00 ,  A61K31/19 ,  A61K31/195 ,  A61K31/235 ,  A61K31/38 ,  A61K31/40 ,  A61K31/405 ,  A61K31/415 ,  A61K31/42 ,  A61K31/425 ,  A61K31/44 ,  A61K31/54 ,  A61K31/60

摘要： This invention pertains to the novel use of anti-rheumatoid arthritic drugs in the treatment of dementia. A method of treating dementia in human beings which comprises administering to the human being a therapeutic amount of a non-steroidal anti-inflammatory drug (NSAID) which has the ability to inhibit prostaglandin synthesis in the human being.

摘要翻译： 本发明涉及抗风湿关节炎药物在治疗痴呆症中的新用途。 一种治疗人类痴呆症的方法，其包括向人体施用治疗量的非甾体抗炎药（NSAID），其具有抑制人类前列腺素合成的能力。

公开(公告)号：US10107588B2

公开(公告)日：2018-10-23

申请号：US14045220

申请日：2013-10-03

申请人： Joseph Rogers

发明人： Joseph Rogers

IPC分类号： F41C33/02 ,  F41C33/04

摘要： The present invention describes to a new and improved handgun holster that provides concealment of and easy access to the firearm when worn on the torso. The device may be worn at different levels along the torso including that of: deep concealment, inside the waistband, and at the midsection of the torso. The holster includes a protective back that acts to guide the user to proper hand placement when drawing the firearm, as the back plate transforms into a cone shape when the user's thumb is pressed against the protective plate of the holster to remove the firearm and the user's fingers are correctly placed along the opposing side of the weapon grip during the drawing act. The handgun holster further acts as a storage compartment by folding the back plate over the grip of a firearm and wrapping and securing the attachment arms around the holster.

公开(公告)号：US20140097216A1

公开(公告)日：2014-04-10

申请号：US14045220

申请日：2013-10-03

申请人： Joseph Rogers

发明人： Joseph Rogers

IPC分类号： F41C33/02

CPC分类号： F41C33/0209 ,  F41C33/02 ,  F41C33/0227 ,  F41C33/0263 ,  F41C33/046 ,  F41C33/048

摘要： The present invention describes to a new and improved handgun holster that provides concealment of and easy access to the firearm when worn on the torso. The device may be worn at different levels along the torso including that of: deep concealment, inside the waistband, and at the midsection of the torso. The holster includes a protective back that acts to guide the user to proper hand placement when drawing the firearm, as the back plate transforms into a cone shape when the user's thumb is pressed against the protective plate of the holster to remove the firearm and the user's fingers are correctly placed along the opposing side of the weapon grip during the drawing act. The handgun holster further acts as a storage compartment by folding the back plate over the grip of a firearm and wrapping and securing the attachment arms around the holster.

摘要翻译： 本发明描述了一种新的和改进的手枪枪套，当佩戴在躯干上时，提供了对枪支的隐藏和容易的接近。 该装置可以沿着躯干穿着不同的水平，包括：深层隐藏，腰带内部和躯干中部。 皮套包括一个保护背部，用于引导用户在绘制枪支时进行适当的手部放置，因为当用户的拇指按压在皮套的保护板上时背板转换成圆锥形，以移除枪支，并且用户的 手指在绘图动作期间沿着武器夹具的相对侧正确放置。 手枪套还通过将背板折叠在枪支的手柄上并且将附接臂包围并固定在机架上而进一步充当储藏室。

公开(公告)号：US20110086925A1

公开(公告)日：2011-04-14

申请号：US12797591

申请日：2010-06-09

申请人： Diego Mastroeni ,  Joseph Rogers ,  Andrew Grover ,  Paul D. Coleman

发明人： Diego Mastroeni ,  Joseph Rogers ,  Andrew Grover ,  Paul D. Coleman

IPC分类号： A61K47/00 ,  G01N33/53 ,  C12Q1/68 ,  A61P25/28

CPC分类号： G01N33/5308 ,  C12Q1/6883 ,  G01N33/56972 ,  G01N33/6896 ,  G01N2800/2821

摘要： Various embodiments provide methods for the detection, the diagnosis, and/or the progression monitoring of Alzheimer's disease by observing the epigenetic markers in leukocytes. Methods for determining a state of Alzheimer's disease are provided. Accordingly, these methods can comprise the steps of placing a sample comprising at least one blood component onto a substrate labeling the sample to identify at least one epigenetic marker; determining an amount of the at least one epigenetic marker; comparing the amount to a reference value; and determining a state of Alzheimer's disease.

摘要翻译： 各种实施方案通过观察白细胞中的表观遗传标记来提供用于阿尔茨海默氏病的检测，诊断和/或进展监测的方法。 提供了确定阿尔茨海默病状态的方法。 因此，这些方法可以包括以下步骤：将包含至少一种血液成分的样品放置在标记样品的底物上，以鉴定至少一种表观遗传标记; 确定所述至少一种表观遗传标记的量; 将数量与参考值进行比较; 并确定阿尔茨海默病的状态。

公开(公告)号：US20060205024A1

公开(公告)日：2006-09-14

申请号：US11371667

申请日：2006-03-08

申请人： Joseph Rogers ,  Rena Li ,  Diego Mastroeni ,  Andrew Grover ,  Marwan Sabbagh

发明人： Joseph Rogers ,  Rena Li ,  Diego Mastroeni ,  Andrew Grover ,  Marwan Sabbagh

IPC分类号： G01N33/537 ,  G01N33/53 ,  G01N33/543 ,  G01N33/00

CPC分类号： G01N33/6896 ,  G01N2800/2821

摘要： A method or technique of detecting, diagnosing, monitoring, and evaluating a neurodegenerative disease, such as Alzheimer's disease, in a human body fluid is disclosed. The invention provides for a method of detecting amyloid peptides associated with erythrocytes and amyloid peptide complement complexes, as a diagnostic test for the detection, monitoring, evaluation or diagnosis of Alzheimer's disease and amyloid-based neurodegenerative diseases. More specifically the invention is directed to a method for detecting presence and amount of amyloid peptides such as amyloid beta (“Aβ”) and Aβ complement complexes, and related complement complexes and compounds with a role in neurodegenerative diseases, in an erythrocyte fraction of a human bodily fluid.

摘要翻译： 公开了一种在人体液中检测，诊断，监测和评价神经变性疾病如阿尔茨海默氏病的方法或技术。 本发明提供了检测与红细胞和淀粉样蛋白肽补体复合物相关的淀粉样肽的方法，作为阿尔茨海默氏病和淀粉样蛋白基神经变性疾病的检测，监测，评价或诊断的诊断试验。 更具体地，本发明涉及一种用于检测淀粉样肽如淀粉样蛋白β（“Abeta”）和Abeta补体复合物的存在和量的方法，以及相关的补体复合物和在神经变性疾病中起作用的化合物，其在红细胞分数 人体液体