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公开(公告)号：US08920867B2
公开(公告)日：2014-12-30
申请号：US13239942
申请日：2011-09-22
申请人： Joshua Stopek , Garrett Ebersole , Amin Elachchabi , Daniel Broom
发明人： Joshua Stopek , Garrett Ebersole , Amin Elachchabi , Daniel Broom
CPC分类号： A61K9/7007 , A61K9/0024 , A61K47/34 , A61L31/16 , A61L2300/402 , A61L2300/416
摘要： The present disclosure relates to self-supporting films for delivery of a therapeutic agent containing at least one hydrophobic polymer and at least one therapeutic agent. Methods of forming the self-supporting films are also disclosed.
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公开(公告)号：US08758798B2
公开(公告)日：2014-06-24
申请号：US13051261
申请日：2011-03-18
申请人： Joshua Stopek , Amin Elachchabi , Daniel Broom , Garrett Ebersole
发明人： Joshua Stopek , Amin Elachchabi , Daniel Broom , Garrett Ebersole
CPC分类号： A61K9/7007 , A61B17/00234 , A61F2/0063 , A61F2250/003 , A61F2250/0035 , A61F2250/0067 , A61K9/0024 , A61L27/54 , A61L27/58 , C07K5/06078
摘要： Surgical implants are provided which include a film comprising a first therapeutic agent and a mesh comprising a second therapeutic agent. The surgical implant includes a film in direct contact with a mesh. The first therapeutic agent may be released at a first rate and the second therapeutic agent may be released at a second rate.
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公开(公告)号：US09211175B2
公开(公告)日：2015-12-15
申请号：US13173659
申请日：2011-06-30
CPC分类号： A61F2/0063 , A61F2/0045 , A61F2210/0004 , A61F2250/0067 , A61F2250/0071
摘要： The present disclosure relates to self-detachable medical devices containing a detachable film layer and polymeric film layer.
摘要翻译： 本公开涉及包含可拆卸膜层和聚合物膜层的可自行拆卸的医疗装置。
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公开(公告)号：US20120095418A1
公开(公告)日：2012-04-19
申请号：US13240032
申请日：2011-09-22
申请人： Joshua Stopek , Garrett Ebersole , Amin Elachchabi , Daniel Broom
发明人： Joshua Stopek , Garrett Ebersole , Amin Elachchabi , Daniel Broom
IPC分类号： A61K31/445 , A61P29/00 , A61M35/00 , A61K9/70
CPC分类号： A61K9/7007 , A61K9/0024 , A61K47/34 , A61L31/16 , A61L2300/402 , A61L2300/416
摘要： The present disclosure relates to self-supporting films for delivery of a therapeutic agent containing at least one hydrophobic polymer and at least one therapeutic agent. Methods of forming the self-supporting films are also disclosed.
摘要翻译： 本公开涉及用于递送含有至少一种疏水性聚合物和至少一种治疗剂的治疗剂的自支撑膜。 还公开了形成自支撑膜的方法。
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5.发明申请公开(公告)号：US20120094004A1
公开(公告)日：2012-04-19
申请号：US13239942
申请日：2011-09-22
申请人： Joshua Stopek , Garrett Ebersole , Amin Elachchabi , Daniel Broom
发明人： Joshua Stopek , Garrett Ebersole , Amin Elachchabi , Daniel Broom
CPC分类号： A61K9/7007 , A61K9/0024 , A61K47/34 , A61L31/16 , A61L2300/402 , A61L2300/416
摘要： The present disclosure relates to self-supporting films for delivery of a therapeutic agent containing at least one hydrophobic polymer and at least one therapeutic agent. Methods of forming the self-supporting films are also disclosed.
摘要翻译： 本公开涉及用于递送含有至少一种疏水性聚合物和至少一种治疗剂的治疗剂的自支撑膜。 还公开了形成自支撑膜的方法。
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公开(公告)号：US20120009240A1
公开(公告)日：2012-01-12
申请号：US13173718
申请日：2011-06-30
申请人： Joshua Stopek , Daniel Broom , Amin Elachchabi , Garrett Ebersole
发明人： Joshua Stopek , Daniel Broom , Amin Elachchabi , Garrett Ebersole
IPC分类号： A61K9/70 , A61K9/00 , A61K31/519 , A61P23/02 , A61K31/445 , A61K31/165 , A61M35/00 , A61P35/00 , A61K33/24 , A61K31/513
CPC分类号： A61K9/0024 , A61K9/7007 , A61K31/165 , A61K31/445 , A61K31/513 , A61K31/519
摘要： The present disclosure relates to self-supporting films for delivery of a therapeutic agent containing at least one hydrophobic polymer and at least one therapeutic agent. Methods of forming the multilayer films are also disclosed.
摘要翻译： 本公开涉及用于递送含有至少一种疏水性聚合物和至少一种治疗剂的治疗剂的自支撑膜。 还公开了形成多层膜的方法。
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公开(公告)号：US09861590B2
公开(公告)日：2018-01-09
申请号：US13240032
申请日：2011-09-22
申请人： Joshua Stopek , Garrett Ebersole , Amin Elachchabi , Daniel Broom
发明人： Joshua Stopek , Garrett Ebersole , Amin Elachchabi , Daniel Broom
CPC分类号： A61K9/7007 , A61K9/0024 , A61K47/34 , A61L31/16 , A61L2300/402 , A61L2300/416
摘要： The present disclosure relates to self-supporting films for delivery of a therapeutic agent containing at least one hydrophobic polymer and at least one therapeutic agent. Methods of forming the self-supporting films are also disclosed.
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公开(公告)号：US09216240B2
公开(公告)日：2015-12-22
申请号：US12987259
申请日：2011-01-10
申请人： Daniel Broom , Joshua Stopek , Amin Elachchabi
发明人： Daniel Broom , Joshua Stopek , Amin Elachchabi
CPC分类号： A61L31/16 , A61F2/0063 , A61L15/44 , A61L27/54 , A61L2300/402 , A61L2300/45 , A61L2300/602
摘要： A medical device includes a substrate having at least one surface. The surface has a central portion and a peripheral portion. At least one bioactive agent is disposed over at least a portion of the surface. The medical device having a concentration gradient of the at least one bioactive between the central and peripheral portions.
摘要翻译： 医疗装置包括具有至少一个表面的基底。 表面具有中心部分和周边部分。 在表面的至少一部分上设置至少一种生物活性剂。 所述医疗装置具有在所述中央部分和所述周边部分之间的所述至少一种生物活性物的浓度梯度。
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公开(公告)号：US08758800B2
公开(公告)日：2014-06-24
申请号：US13051395
申请日：2011-03-18
申请人： Joshua Stopek , Amin Elachchabi , Daniel Broom , Garrett Ebersole
发明人： Joshua Stopek , Amin Elachchabi , Daniel Broom , Garrett Ebersole
CPC分类号： A61F2/0063 , A61B17/00234 , A61F2250/003 , A61F2250/0067 , A61K9/0024 , A61L27/54 , A61L27/58 , C07K5/06078
摘要： Surgical implants are provided which include a film comprising a first therapeutic agent and a mesh comprising a second therapeutic agent. The surgical implant includes a film in direct contact with a mesh. The first therapeutic agent may be released at a first rate and the second therapeutic agent may be released at a second rate.
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公开(公告)号：US20110236460A1
公开(公告)日：2011-09-29
申请号：US13051395
申请日：2011-03-18
申请人： Joshua Stopek , Amin Elachchabi , Daniel Broom , Garrett Ebersole
发明人： Joshua Stopek , Amin Elachchabi , Daniel Broom , Garrett Ebersole
IPC分类号： A61K9/70 , A61K31/445 , A61K31/165 , A61P29/00 , A61P23/02
CPC分类号： A61F2/0063 , A61B17/00234 , A61F2250/003 , A61F2250/0067 , A61K9/0024 , A61L27/54 , A61L27/58 , C07K5/06078
摘要： Surgical implants of the present disclosed include a film comprising a first therapeutic agent and a mesh comprising a second therapeutic agent. The surgical implant includes a film in direct contact with a mesh. The first therapeutic agent may be released at a first rate and the second therapeutic agent may be released at a second rate.
摘要翻译： 本公开的外科植入物包括包含第一治疗剂的膜和包含第二治疗剂的网。 手术植入物包括与网状物直接接触的膜。 第一治疗剂可以以第一速率释放，并且第二治疗剂可以以第二速率释放。
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