专利检索 ap:("Joslin Diabetes Center, Inc.") AND inv:"George Liang King" 第 1 页

1.

发明申请
Methods to Accelerate Wound Healing in Diabetic Subjects 审中-公开

公开(公告)号：US20180066327A1

公开(公告)日：2018-03-08

申请号：US15557740

申请日：2016-03-14

申请人： Joslin Diabetes Center, Inc.

发明人： George Liang King , Mogher Khamaisi , Hillary A. Keenan

IPC分类号： A61K35/33 , A61K35/36 , A61K35/545 , A61K38/10 , C12N15/113 , C12N5/077 , C12N15/52

CPC分类号： C12Y207/10002 , A61K35/33 , A61K35/36 , A61K35/545 , A61K38/10 , A61K38/1709 , A61K48/00 , C12N5/0656 , C12N15/1137 , C12N15/52 , C12N2310/14 , C12N2310/141 , C12N2501/727

摘要： Methods of accelerating wound healing in diabetic subjects using autologous cell grafts treated to specifically inhibit Protein Kinase C delta (PKC6), as well as cells and compositions for use in these methods. Provided herein are methods for preparing cells for application to a wound in a diabetic subject. The methods include incubating the cells in the presence of an effective amount of a PKC6 inhibitor.

2.

发明申请
RETINOL-BINDING PROTEIN 3 (RBP3) AS A PROTECTIVE FACTOR IN NON-DIABETIC RETINAL DEGENERATION 有权

公开(公告)号：US20210000855A1

公开(公告)日：2021-01-07

申请号：US16866346

申请日：2020-05-04

申请人： Joslin Diabetes Center, Inc.

发明人： George Liang King , Hillary A. Keenan

IPC分类号： A61K31/711 , A61K38/17 , A61K45/06 , A61K35/76 , C12N15/86 , A61K48/00 , A61K31/7088 , A61K38/16 , C12N15/861

摘要： Methods for increasing retinal thickness in a non-diabetic mammal, comprising administering to the mammal one or both of: (i) a composition comprising RBP3 polypeptide, and/or (ii) a composition comprising a nucleic acid encoding an RBP3 polypeptide.