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公开(公告)号:US08728470B2
公开(公告)日:2014-05-20
申请号:US13287642
申请日:2011-11-02
IPC分类号: A61K39/395 , C07K16/00
CPC分类号: C07K16/3007 , A61K2039/505 , C07K2317/622 , C07K2319/00
摘要: The present invention relates to CAB molecules, ADEPT constructs directed against CEA, and their use in therapy.
摘要翻译: 本发明涉及CAB分子,针对CEA的ADEPT构建体及其在治疗中的用途。
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公开(公告)号:US20120107314A1
公开(公告)日:2012-05-03
申请号:US13287642
申请日:2011-11-02
IPC分类号: A61K39/395 , C07H21/04
CPC分类号: C07K16/3007 , A61K2039/505 , C07K2317/622 , C07K2319/00
摘要: The present invention relates to CAB molecules, ADEPT constructs directed against CEA, and their use in therapy.
摘要翻译: 本发明涉及CAB分子,针对CEA的ADEPT构建体及其在治疗中的用途。
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公开(公告)号:US20110160440A1
公开(公告)日:2011-06-30
申请号:US10581106
申请日:2004-12-10
CPC分类号: C07K16/3007 , A61K2039/505 , C07K16/40 , C07K2317/565 , C07K2317/622 , C07K2317/92 , C07K2317/94 , C07K2319/00
摘要: The present invention relates to CAB molecules, ADEPT constructs directed against CEA, and their use in diagnosis and therapy.
摘要翻译: 本发明涉及CAB分子,针对CEA的ADEPT构建体及其在诊断和治疗中的用途。
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公开(公告)号:US08088609B2
公开(公告)日:2012-01-03
申请号:US10590870
申请日:2005-04-12
IPC分类号: C07K16/00
CPC分类号: C07K16/3007 , A61K2039/505 , C07K2317/622 , C07K2319/00
摘要: The present invention relates to CAB molecules, ADEPT constructs directed against CEA, and their use in therapy.
摘要翻译: 本发明涉及CAB分子,针对CEA的ADEPT构建体及其在治疗中的用途。
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公开(公告)号:US20080096810A1
公开(公告)日:2008-04-24
申请号:US10590870
申请日:2005-04-12
CPC分类号: C07K16/3007 , A61K2039/505 , C07K2317/622 , C07K2319/00
摘要: The present invention relates to CAB molecules, ADEPT constructs directed against CEA, and their use in therapy.
摘要翻译: 本发明涉及CAB分子,针对CEA的ADEPT构建体及其在治疗中的用途。
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公开(公告)号:US20120094357A1
公开(公告)日:2012-04-19
申请号:US13323291
申请日:2011-12-12
IPC分类号: C12N9/96
CPC分类号: B82Y5/00 , A61K47/6899 , A61K2039/505 , C07K16/30 , C07K2317/622
摘要: The present invention relates to TAB molecules, ADEPT constructs directed against TAG-72, and their use in therapy.
摘要翻译: 本发明涉及TAB分子,针对TAG-72的ADEPT构建体及其在治疗中的应用。
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公开(公告)号:US08188240B2
公开(公告)日:2012-05-29
申请号:US13323291
申请日:2011-12-12
IPC分类号: C07K16/00
CPC分类号: B82Y5/00 , A61K47/6899 , A61K2039/505 , C07K16/30 , C07K2317/622
摘要: The present invention relates to TAB molecules, ADEPT constructs directed against TAG-72, and their use in therapy.
摘要翻译: 本发明涉及TAB分子,针对TAG-72的ADEPT构建体及其在治疗中的应用。
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公开(公告)号:US08101728B2
公开(公告)日:2012-01-24
申请号:US11885492
申请日:2006-04-21
IPC分类号: C07K16/00
CPC分类号: B82Y5/00 , A61K47/6899 , A61K2039/505 , C07K16/30 , C07K2317/622
摘要: The present invention relates to TAB molecules, ADEPT constructs directed against TAG-72, and their use in therapy.
摘要翻译: 本发明涉及TAB分子,针对TAG-72的ADEPT构建体及其在治疗中的应用。
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公开(公告)号:US20090203104A1
公开(公告)日:2009-08-13
申请号:US11885492
申请日:2006-04-21
IPC分类号: C12N9/96
CPC分类号: B82Y5/00 , A61K47/6899 , A61K2039/505 , C07K16/30 , C07K2317/622
摘要: The present invention relates to TAB molecules, ADEPT constructs directed against TAG-72, and their use in therapy.
摘要翻译: 本发明涉及TAB分子,针对TAG-72的ADEPT构建体及其在治疗中的应用。
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公开(公告)号:US10421798B2
公开(公告)日:2019-09-24
申请号:US14379192
申请日:2012-07-11
申请人: Volker Schellenberger , Pei-Yun Chang , Fatbardha Varfaj , Sheng Ding , Joshua Silverman , Chia-wei Wang , Benjamin Spink , Willem P. Stemmer , Volker Schellenberger , Nathan Geething , John Kulman , Tongyao Liu , Garabet G. Toby , Haiyan Jiang , Robert Peters , Deping Wang , Baisong Mei
发明人: Volker Schellenberger , Pei-Yun Chang , Fatbardha Varfaj , Sheng Ding , Joshua Silverman , Chia-wei Wang , Benjamin Spink , Willem P. Stemmer , Nathan Geething , John Kulman , Tongyao Liu , Garabet G. Toby , Haiyan Jiang , Robert Peters , Deping Wang , Baisong Mei
IPC分类号: C07K14/755 , A61K38/00
摘要: The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.
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