公开(公告)号：US20090259280A1

公开(公告)日：2009-10-15

申请号：US12251008

申请日：2008-10-14

申请人： Kevin Wilkin ,  Jeryle Walter ,  Timothy Raymond Odell ,  Jeremy Koff ,  Morten Hansen ,  Arkady Glukhovsky ,  Timothy Deer ,  Julie S. Armstrong

发明人： Kevin Wilkin ,  Jeryle Walter ,  Timothy Raymond Odell ,  Jeremy Koff ,  Morten Hansen ,  Arkady Glukhovsky ,  Timothy Deer ,  Julie S. Armstrong

IPC分类号： A61N1/05

CPC分类号： A61N1/057 ,  A61N1/0558

摘要： An apparatus includes a coupling portion, a bioerodible anchor portion and a bioerodable retainer. The coupling portion is configured to be coupled to an electrical conductor. The bioerodible retention portion is adjacent to the coupling portion and is moveable from a collapsed configuration to an expanded configuration. The bioerodible retention portion is configured to anchor the electrical conductor with respect to body tissue when the bioerodible retention portion is in its expanded configuration. The bioerodible anchor portion is formulated to erode when disposed within the body tissue at a first rate. The bioerodible retainer is coupled to the bioerodible anchor portion and is configured to inhibit movement of the bioerodible anchor portion from the collapsed configuration to the expanded configuration. The bioerodible retainer is formulated to erode when disposed within the body tissue at a second rate greater than the first rate.

摘要翻译： 一种装置包括联接部分，生物可蚀解锚定部分和可生物侵蚀的保持器。 耦合部分被配置为耦合到电导体。 生物可蚀解保留部分与联接部分相邻并且可从折叠构型移动到扩张构型。 生物可蚀解保持部分构造成当生物可蚀解保持部分处于其膨胀构型时相对于身体组织锚固电导体。 当以第一速率设置在身体组织内时，配制生物可蚀解锚固部分以侵蚀。 生物可蚀性保持器联接到生物可蚀解锚定部分并且被配置成禁止生物可蚀解锚固部分从折叠构型到膨胀构型的移动。 配置生物可蚀性保持器时，以大于第一速率的第二速率设置在身体组织内时被腐蚀。

公开(公告)号：US20090099612A1

公开(公告)日：2009-04-16

申请号：US12251014

申请日：2008-10-14

申请人： Julie S. Armstrong

发明人： Julie S. Armstrong

IPC分类号： A61N1/36 ,  A61N1/05

CPC分类号： A61N1/05 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/602 ,  A61N1/0568

摘要： An apparatus includes an elongate member having a proximal end portion and a distal end portion. The proximal end portion is configured to receive an electrical current from a current source. The elongate member is configured to transmit the electrical current from the proximal end portion to the distal end portion. At least a portion of the elongate member is configured to be disposed within a body of a patient. An electrode is coupled to the distal end portion of the elongate member. The electrode is configured to transmit a portion of the electrical current from the distal end portion of the elongate member to a target bodily tissue. A coating is disposed on at least a portion of the elongate member. The coating is formulated to release at least one of a therapeutic agent, a conductive agent, and/or an insulative agent into the body of the patient in response to the electrical current being transmitted from the proximal end portion to the distal end portion of the elongate member.

摘要翻译： 一种装置包括具有近端部分和远端部分的细长部件。 近端部分构造成从电流源接收电流。 细长构件构造成将电流从近端部分传递到远端部分。 细长构件的至少一部分构造成设置在患者的身体内。 电极连接到细长构件的远端部分。 电极被配置为将电流的一部分从细长构件的远端部分传递到目标身体组织。 在细长构件的至少一部分上设置涂层。 将涂层配制成将治疗剂，导电剂和/或绝缘剂中的至少一种释放到患者体内，以响应于电流从基端部传递到远端部分 细长构件。