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    Neurostimulation leads for trial nerve stimulation and methods of use
    5.
    发明授权
    Neurostimulation leads for trial nerve stimulation and methods of use 有权

    公开(公告)号：US12042662B2

    公开(公告)日：2024-07-23

    申请号：US17396260

    申请日：2021-08-06

    申请人： Axonics, Inc.

    发明人： Henry Lee ,  David Marvicsin ,  Trishna Dave

    IPC分类号： A61N1/05 ,  A61N1/36 ,  A61N1/372 ,  A61N1/375

    CPC分类号： A61N1/37518 ,  A61N1/0558 ,  A61N1/36062 ,  A61N1/37205 ,  A61N1/36071 ,  A61N1/36107

    摘要： Devices and methods for providing neurostimulation to a patient, particularly in trial systems assessing suitability of a permanently implanted neurostimulation, are provided herein. In one aspect, a trial neurostimulation lead includes a coiled conductor coupled to a proximal contact connector having a retention flange that withstands tensile force from tension in the lead so as to maintain the electrical connection during a trial period. In another aspect, a trial neurostimulation system includes a lead extension that includes a regression stopper between the implanted distal connector and proximal lead disposed outside the body to prevent regression of the lead through a secondary incision, thereby preventing infection and facilitating explant of the system. Methods of assembling and utilizing such leads and systems are detailed herein.

    IMPLANTABLE MEDICAL LEAD AND RELATED DEVICES AND METHODS
    6.
    发明公开
    IMPLANTABLE MEDICAL LEAD AND RELATED DEVICES AND METHODS 审中-公开

    公开(公告)号：US20240238587A1

    公开(公告)日：2024-07-18

    申请号：US18559238

    申请日：2022-05-06

    申请人： Foresite Capital Holdings, LLC

    发明人： Jon Obray ,  Rick Obray ,  Eric Olson

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0553 ,  A61N1/0558

    摘要： An implantable medical lead for electrical stimulation may include a body, which may include a flexible distal end, a flexible proximal end, and a rigid portion extending between the flexible distal end and the flexible proximal end. The body may include an aperture extending through the flexible distal end and the flexible proximal end and configured to receive a guidewire therethrough. The implantable medical lead may include an electrode coupled to the rigid portion and an electrical conductor electrically connected to the electrode and extending from the electrode through the flexible proximal end. A medical anchor to secure the implantable medical lead may include a body and a clamp element configured to move between an open position and a closed position. A surgical instrument to implant the implantable medical lead may include a first arm having a first clamp surface and a second arm having a second clamp surface.

    SUBCUTANEOUS DEVICE WITH ANCHORING ARMS
    7.
    发明公开
    SUBCUTANEOUS DEVICE WITH ANCHORING ARMS 审中-公开

    公开(公告)号：US20240226582A9

    公开(公告)日：2024-07-11

    申请号：US18493567

    申请日：2023-10-24

    申请人： Calyan Technologies, Inc.

    发明人： Yatheendhar D. Manicka

    IPC分类号： A61N1/375 ,  A61N1/05 ,  A61N1/36 ,  A61N1/365

    CPC分类号： A61N1/37518 ,  A61N1/0558 ,  A61N1/36135 ,  A61N1/365

    摘要： A subcutaneously implantable device includes a housing, a first anchoring arm attached to the housing that is configured to anchor the device to a muscle, a bone, and/or a first tissue, and a first prong with a proximal end attached to the housing and a distal end extending away from the housing that is configured to be positioned adjacent to or contact an organ, a nerve, or a second tissue. A first electrode is on the distal end of the first prong that is configured to contact the organ, the nerve, and/or the second tissue. Circuitry in the housing is in electrical communication with the first electrode and is configured to sense an electrical signal from the organ, the nerve, and/or the second tissue through the first electrode, and/or deliver electrical stimulation to the organ, the nerve, and/or the second tissue through the first electrode.

    Closed-loop spinal cord electrical stimulation system
    10.
    发明授权
    Closed-loop spinal cord electrical stimulation system 有权

    公开(公告)号：US12023493B2

    公开(公告)日：2024-07-02

    申请号：US17606427

    申请日：2020-01-09

    申请人： SOOCHOW UNIVERSITY

    发明人： Yaobo Liu ,  Dan Yang ,  Wei Yang ,  Kai Zhou ,  Wei Wei ,  Hui Zhang

    IPC分类号： A61N1/05 ,  A61B5/00 ,  A61B5/389 ,  A61N1/36

    CPC分类号： A61N1/36003 ,  A61B5/389 ,  A61B5/4848 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/36062 ,  A61N1/36153 ,  A61N1/36171 ,  A61B2503/40 ,  A61B2503/42

    摘要： A closed-loop spinal cord electrical stimulation system includes a spinal epidural electrical stimulation electrode, a low limb electrical stimulation electrode, a closed-loop electrical stimulator and a controller. The spinal epidural electrical stimulation electrode, the low limb electrical stimulation electrode and the controller are electrically connected to the closed-loop electrical stimulator respectively. The spinal epidural electrical stimulation electrode is used for applying a first electrical stimulation to the spinal epidural site, and the low limb electrical stimulation electrode is used for applying a second electrical stimulation to a low limb. The voltage of the first electric stimulation is 400-600 mV, the voltage of the second electric stimulation is 1 V-1.5 V, and the stimulation frequency of the both is 10-20 Hz. The stimulation system can send electrophysiological signals similar to sensorimotor neural circuitry to the subject with spinal cord injury, and can activate and remodel the neural circuit.