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    Medical electrical lead
    5.
    发明授权
    Medical electrical lead 有权
    医用电线

    公开(公告)号：US08694128B2

    公开(公告)日：2014-04-08

    申请号：US12020479

    申请日：2008-01-25

    申请人： Kevin R. Seifert ,  Gregory A. Boser

    发明人： Kevin R. Seifert ,  Gregory A. Boser

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0568 ,  A61N1/0575

    摘要： A medical device lead is presented. One embodiment of the claimed invention includes a lead body, a conductor, and a flexible component. The lead body includes a proximal end and a distal end. The conductor is coupled to the lead body. A sleeve is coupled to the distal end of the lead body. The flexible component is coupled to the distal end of the sleeve. The distal end of the flexible component includes an outer diameter that is greater than the outer diameter of the proximal end.

    摘要翻译： 提供医疗器械引线。 要求保护的发明的一个实施例包括引线体，导体和柔性部件。 引线体包括近端和远端。 导体耦合到引线体。 套筒联接到引线主体的远端。 柔性部件联接到套筒的远端。 柔性部件的远端包括大于近端的外径的外径。

    Anti-infective medical device
    6.
    发明授权
    Anti-infective medical device 有权
    抗感染医疗器械

    公开(公告)号：US08691258B2

    公开(公告)日：2014-04-08

    申请号：US11008445

    申请日：2004-12-09

    申请人： Kenneth T. Heruth ,  Christopher M. Hobot ,  William J. Hooper ,  Mark S. Lent ,  Ruchika Singhal ,  Robert M. Skime ,  Randall V. Sparer ,  Maura G. Donovan ,  William J. Bertrand

    发明人： Kenneth T. Heruth ,  Christopher M. Hobot ,  William J. Hooper ,  Mark S. Lent ,  Ruchika Singhal ,  Robert M. Skime ,  Randall V. Sparer ,  Maura G. Donovan ,  William J. Bertrand

    IPC分类号： A61F13/00 ,  A01N25/00

    CPC分类号： A61N1/05 ,  A61N1/0568 ,  A61N1/375

    摘要： Implantable medical devices (IMDS) having anti-infective properties are described. Anti-infective agents are disposed in, on, or about at least a portion of a surface of the medical device. The anti-infective agents are disposed in or on a vehicle, which may be in the form of a coating layer or covering. The vehicle may be biodegradable so that, over time, the anti-infective agent is removed from a tissue location into which the device is implanted, reducing the likelihood that microorganisms resistant to the anti-infective agent will develop. IMDs having an anti-infective agent and an anti-activity agent disposed therein, thereabout, or thereon are also described. The anti-activity agent interferes with the activity of the anti-infective agent, may be released from a surface at the IMD at a time when activity of the anti-infective agent is no longer desired, and may reduce the likelihood that microorganisms resistant to the anti-infective agent will develop.

    摘要翻译： 描述具有抗感染性的植入式医疗装置（IMDS）。 抗感染剂设置在医疗装置的表面的至少一部分上，其上或附近。 抗感染剂设置在车辆中或车辆上，其可以是涂层或覆盖物的形式。 载体可以是可生物降解的，使得随着时间的推移，抗感染剂从植入装置所在的组织位置移除，降低了抗感染剂抗微生物的可能性。 还描述了其上设置有抗感染剂和抗活性剂的IMD，其上或其上。 干扰抗感染剂的活性的抗活性剂可以在不再需要抗感染剂的活性的时候从IMD的表面释放，并且可能降低抗微生物抗性的可能性 抗感染剂会发展。

    LEADLESS IMPLANTABLE MEDICAL DEVICE WITH OSMOTIC PUMP
    7.
    发明申请
    LEADLESS IMPLANTABLE MEDICAL DEVICE WITH OSMOTIC PUMP 有权
    无菌可塑性医疗器械与OSMOTIC PUMP

    公开(公告)号：US20120290025A1

    公开(公告)日：2012-11-15

    申请号：US13106664

    申请日：2011-05-12

    申请人： John G. Keimel

    发明人： John G. Keimel

    IPC分类号： A61M37/00 ,  A61N1/36

    CPC分类号： A61N1/3756 ,  A61B5/0006 ,  A61B5/0245 ,  A61B5/686 ,  A61M31/002 ,  A61N1/0568 ,  A61N1/0575 ,  A61N1/3712 ,  A61N1/37247 ,  A61N1/37282

    摘要： Techniques for delivering genetic material to a target tissue site of a patient via a leadless implantable medical device that includes a pump and a stimulation energy delivery element are described. In some examples, delivery of genetic material to the target tissue site causes transgene expression of tissue at the target tissue site, which may result in generation of new cells or modified properties of existing cells of the target tissue site, facilitating more effective and efficient treatment of a disorder of the patient.

    摘要翻译： 描述了通过包括泵和刺激能量递送元件的无引导可植入医疗装置将遗传物质递送到患者的靶组织部位的技术。 在一些实例中，将遗传物质递送至靶组织部位导致靶组织部位的组织的转基因表达，这可能导致新细胞的产生或靶组织部位现有细胞的修饰性质，促进更有效和有效的治疗 的病人的病症。

    NEUROSTIMULATION SYSTEM
    8.
    发明申请
    NEUROSTIMULATION SYSTEM 有权
    神经系统

    公开(公告)号：US20120197370A1

    公开(公告)日：2012-08-02

    申请号：US13402786

    申请日：2012-02-22

    申请人： Daniel H. Kim ,  Mir A. Imran

    发明人： Daniel H. Kim ,  Mir A. Imran

    IPC分类号： A61N1/05

    CPC分类号： A61N1/36071 ,  A61M5/142 ,  A61M25/06 ,  A61M2210/1003 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/0568 ,  A61N1/36017 ,  A61N1/36021 ,  A61N1/36067 ,  A61N1/36139 ,  A61N1/36171

    摘要： Some embodiments of the present invention provide neurostimulation systems and components for selective stimulation and/or neuromodulation of one or more dorsal root ganglia through implantation of an electrode on, in or around a dorsal root ganglia. Some other embodiments of the present invention provide neurostimulation systems adapted for selective neurostimulation of one or more nerve root ganglia as well as techniques for applying neurostimulation to the spinal cord. Still other embodiments of the present invention provide stimulation systems and components for selective stimulation and/or neuromodulation of one or more dorsal root ganglia through implantation of an electrode on, in or around a dorsal root ganglia in combination with a pharmacological agent.

    摘要翻译： 本发明的一些实施方案通过在背根神经节内或周围植入电极来提供用于选择性刺激和/或神经调节一个或多个背根神经节的神经刺激系统和组件。 本发明的一些其他实施方案提供了适用于一种或多种神经根神经节的选择性神经刺激的神经刺激系统以及将神经刺激应用于脊髓的技术。 本发明的其它实施方案通过在背根神经节内或周围植入电极来选择性刺激和/或神经调节一个或多个背根神经节的刺激系统和组件，其与药理学组合。

    Distal portions for medical electrical leads
    9.
    发明授权
    Distal portions for medical electrical leads 有权
    医疗电线的远端部分

    公开(公告)号：US08219212B2

    公开(公告)日：2012-07-10

    申请号：US10923926

    申请日：2004-08-23

    申请人： Ryan T. Bauer ,  Yong D. Zhao

    发明人： Ryan T. Bauer ,  Yong D. Zhao

    IPC分类号： A61N1/372

    CPC分类号： A61N1/057 ,  A61N1/0568 ,  A61N2001/0585

    摘要： A medical electrical lead includes a canted lead body distal portion extending from an approximately straight lead body proximal portion; the canted distal portion includes an approximately straight segment and a hump-like segment extending from a first end, in proximity to the approximately straight segment, to a second end. The lead further includes a first electrode coupled to the approximately straight segment of the distal portion and a second electrode coupled to the distal portion in proximity to a second end of the hump-like segment.

    摘要翻译： 医疗用电线包括：从大致直的铅体近端部延伸的倾斜的铅体远端部; 倾斜的远侧部分包括大致直的部分和从第一端部延伸到大致直线部分的隆起状部分到第二端部。 引线还包括耦合到远端部分的大致直线部分的第一电极和耦合到靠近隆起状部分的第二端的远端部分的第二电极。

    Intra-ventricular substance delivery catheter system
    10.
    发明授权
    Intra-ventricular substance delivery catheter system 有权
    室内物质输送导管系统

    公开(公告)号：US08152757B2

    公开(公告)日：2012-04-10

    申请号：US12495623

    申请日：2009-06-30

    申请人： William E. Webler

    发明人： William E. Webler

    IPC分类号： A61M31/00

    CPC分类号： A61M25/0084 ,  A61N1/0568

    摘要： A guide catheter and a needle catheter are disclosed. The guide catheter construction provides for maximum articulation of the deflectable tip and maximum torque response during rotation. The needle catheter may include a release mechanism that imparts a sudden force to the needle in order to facilitate tissue penetration.

    摘要翻译： 公开了引导导管和针导管。 引导导管结构提供可旋转尖端的最大关节和旋转期间的最大扭矩响应。 针导管可以包括向针施加突然的力以释放组织穿透的释放机构。