专利检索 ap:("Jun Feng" OR "Stephen L. Gwaltney" OR "Robert J. Skene" OR "Mingnam Tang" OR "Sheldon X. Cao" OR "David J. Hossfield" OR "Jeffrey A. Stafford") AND inv:"David J. Hossfield" 第 1 页

1.

发明授权
Substituted isoindoles as glucokinase activators 失效
标题翻译：取代的异吲哚作为葡萄糖激酶激活剂

公开(公告)号：US08394843B2

公开(公告)日：2013-03-12

申请号：US13185166

申请日：2011-07-18

申请人： Jun Feng , Stephen L. Gwaltney , Robert J. Skene , Mingnam Tang , Sheldon X. Cao , David J. Hossfield , Jeffrey A. Stafford

发明人： Jun Feng , Stephen L. Gwaltney , Robert J. Skene , Mingnam Tang , Sheldon X. Cao , David J. Hossfield , Jeffrey A. Stafford

IPC分类号： C07D209/02 , C07D275/02 , A61K31/4035 , A61K31/4168 , C07D231/56 , C07D471/02 , C07D487/04 , A61K31/519 , A61K31/4152 , A61K31/416 , A61K31/437 , A61K31/4985 , A61P13/12

CPC分类号： C07D417/12 , C07D401/12 , C07D471/04 , C07D487/04

摘要： Compounds are provided which have the formula: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture which contain such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds to activate glucokinase.

摘要翻译： 提供了具有下式的化合物：其中变量如本文所定义。还提供含有这些化合物的药物组合物，试剂盒和制品，用于制备化合物的方法和中间体，以及使用该化合物来激活葡糖激酶的方法。