公开(公告)号：US20080038256A1

公开(公告)日：2008-02-14

申请号：US11626055

申请日：2007-01-23

申请人： Junho CHUNG ,  Kisu Kim

发明人： Junho CHUNG ,  Kisu Kim

IPC分类号： A61K39/395 ,  A61P35/00 ,  C07H21/04 ,  C07K16/22 ,  C40B10/00

CPC分类号： C07K16/32 ,  A61K39/39558 ,  A61K2039/505 ,  C07K2317/24 ,  A61K2300/00

摘要： The inventive anti-HGF/SF humanized antibody prepared by displaying on the surface of a phage an anti-HGF/SF chimeric Fab library comprising a set of human antibody light chain variable region (VL) and human antibody heavy chain variable region (VH) which are grafted with heavy chain complementary determining regions (HCDRs) of an anti-HGF/SF antibody of an animal other than human, has the equal or greater binding affinity than that of the parent anti-HGF/SF antibody, the neutralizing activity inhibiting the binding of HGF/SF to its receptor, cMET, while having the reduced immunogenicity in human. Therefore, the inventive anti-HGF/SF humanized antibody can be used for preventing and treating diseases effectively, e.g., cancers, by the action of binding HGF/SF to cMET.

摘要翻译： 通过在噬菌体表面上显示包含一组人抗体轻链可变区（V L L L）和人的抗HGF / SF嵌合Fab文库制备的本发明抗HGF / SF人源化抗体 用除人以外的动物的抗HGF / SF抗体的重链互补决定区（HCDR）接枝的抗体重链可变区（V H H H S）具有相等或更大的结合亲和力 与抗原HGF / SF抗体相比，中和活性抑制HGF / SF与其受体cMET的结合，同时在人体中具有降低的免疫原性。 因此，通过将HGF / SF结合到cMET的作用，本发明的抗HGF / SF人源化抗体可用于有效地预防和治疗疾病，例如癌症。

公开(公告)号：US07718174B2

公开(公告)日：2010-05-18

申请号：US11626055

申请日：2007-01-23

申请人： Junho Chung ,  Kisu Kim

发明人： Junho Chung ,  Kisu Kim

IPC分类号： A61K39/395 ,  C12P21/08

CPC分类号： C07K16/32 ,  A61K39/39558 ,  A61K2039/505 ,  C07K2317/24 ,  A61K2300/00

摘要： The inventive anti-HGF/SF humanized antibody prepared by displaying on the surface of a phage an anti-HGF/SF chimeric Fab library comprising a set of human antibody light chain variable region (VL) and human antibody heavy chain variable region (VH) which are grafted with heavy chain complementary determining regions (HCDRs) of an anti-HGF/SF antibody of an animal other than human, has the equal or greater binding affinity than that of the parent anti-HGF/SF antibody, the neutralizing activity inhibiting the binding of HGF/SF to its receptor, cMET while having the reduced immunogenicity in human. Therefore, the inventive anti-HGF/SF humanized antibody can be used for preventing and treating diseases effectively, e.g., cancers, by the action of binding HGF/SF to cMET.

摘要翻译： 通过在噬菌体表面上显示包含一组人抗体轻链可变区（VL）和人抗体重链可变区（VH）的抗HGF / SF嵌合Fab文库制备的本发明抗HGF / SF人源化抗体， 其与除人以外的动物的抗HGF / SF抗体的重链互补决定区（HCDR）接枝，具有与母体抗HGF / SF抗体相同或更大的结合亲和力，抑制中和活性 HGF / SF与其受体的结合，cMET在人体中具有降低的免疫原性。 因此，通过将HGF / SF结合到cMET的作用，本发明的抗HGF / SF人源化抗体可用于有效地预防和治疗疾病，例如癌症。

公开(公告)号：US09871146B2

公开(公告)日：2018-01-16

申请号：US13560723

申请日：2012-07-27

申请人： Seunghwan Shim ,  Kisu Kim ,  Eunae Yoon ,  Yuju Hwang ,  Younghyun Lee ,  Sangwook Park

发明人： Seunghwan Shim ,  Kisu Kim ,  Eunae Yoon ,  Yuju Hwang ,  Younghyun Lee ,  Sangwook Park

IPC分类号： H01L31/0216 ,  H01L31/0236 ,  H01L31/0224 ,  H01L31/068

CPC分类号： H01L31/02168 ,  H01L31/022433 ,  H01L31/02363 ,  H01L31/068 ,  Y02E10/547

摘要： A solar cell includes a substrate formed of n-type single crystal silicon, an emitter region of a p-type which is positioned at a first surface of the substrate and includes a first emitter region having a first sheet resistance and a second emitter region having a second sheet resistance less than the first sheet resistance, a plurality of surface field regions of the n-type locally positioned at a second surface opposite the first surface of the substrate, a plurality of first electrodes which are positioned only on the second emitter region to be separated from one another and are connected to the second emitter region, and a plurality of second electrodes which are positioned on the plurality of surface field regions to be separated from one another and are connected to the plurality of surface field regions.

公开(公告)号：US20130118571A1

公开(公告)日：2013-05-16

申请号：US13560723

申请日：2012-07-27

申请人： Seunghwan Shim ,  Kisu Kim ,  Eunae Yoon ,  Yuju Hwang ,  Younghyun Lee ,  Sangwook Park

发明人： Seunghwan Shim ,  Kisu Kim ,  Eunae Yoon ,  Yuju Hwang ,  Younghyun Lee ,  Sangwook Park

IPC分类号： H01L31/0224 ,  H01L31/18

CPC分类号： H01L31/02168 ,  H01L31/022433 ,  H01L31/02363 ,  H01L31/068 ,  Y02E10/547

摘要： A solar cell includes a substrate formed of n-type single crystal silicon, an emitter region of a p-type which is positioned at a first surface of the substrate and includes a first emitter region having a first sheet resistance and a second emitter region having a second sheet resistance less than the first sheet resistance, a plurality of surface field regions of the n-type locally positioned at a second surface opposite the first surface of the substrate, a plurality of first electrodes which are positioned only on the second emitter region to be separated from one another and are connected to the second emitter region, and a plurality of second electrodes which are positioned on the plurality of surface field regions to be separated from one another and are connected to the plurality of surface field regions.

摘要翻译： 太阳能电池包括由n型单晶硅形成的衬底，位于衬底的第一表面处的p型发射极区域，并且包括具有第一薄层电阻的第一发射极区域和具有第一发射极区域的第二发射极区域， 小于第一薄层电阻的第二薄层电阻，位于与基板的第一表面相对的第二表面的n型的多个表面场区域，仅位于第二发射极区域上的多个第一电极 彼此分离并连接到第二发射极区域，并且多个第二电极位于多个表面场区域上以彼此分离并且连接到多个表面场区域。

公开(公告)号：US09040813B2

公开(公告)日：2015-05-26

申请号：US13472038

申请日：2012-05-15

申请人： Jongdae Kim ,  Kisu Kim

发明人： Jongdae Kim ,  Kisu Kim

IPC分类号： H01L31/05 ,  H01L31/0224 ,  H01L31/068 ,  H01L31/18

CPC分类号： H01L31/0504 ,  H01L31/022425 ,  H01L31/0512 ,  H01L31/068 ,  H01L31/1804 ,  Y02E10/547 ,  Y02P70/521

摘要： A solar cell module includes a plurality of solar cells each comprising a substrate, an emitter region placed at the substrate, and an anti-reflection region placed on the emitter region. The anti-reflection region includes a first opening region through which part of the emitter region is exposed and one or more second opening regions through which part of the emitter region is exposed. A first electrode is connected to the exposed emitter region of the first opening region through the anti-reflection region by metal plating and a first bus bar is connected to the exposed emitter region of one or more second opening regions through the anti-reflection region by metal plating.

摘要翻译： 太阳能电池模块包括多个太阳能电池，每个太阳能电池包括基板，放置在基板处的发射极区域和放置在发射极区域上的防反射区域。 防反射区域包括第一开口区域，发射区域的一部分被暴露出来，并且一个或多个第二开口区域通过该第一开口区域暴露出发射区域的一部分。 第一电极通过金属电镀通过抗反射区域连接到第一开口区域的暴露的发射极区域，并且第一汇流条通过反射区域通过反射区域连接到一个或多个第二开口区域的暴露的发射极区域， 金属电镀。

公开(公告)号：US20130220400A1

公开(公告)日：2013-08-29

申请号：US13472038

申请日：2012-05-15

申请人： Jongdae Kim ,  Kisu Kim

发明人： Jongdae Kim ,  Kisu Kim

IPC分类号： H01L31/05 ,  H01L31/052

CPC分类号： H01L31/0504 ,  H01L31/022425 ,  H01L31/0512 ,  H01L31/068 ,  H01L31/1804 ,  Y02E10/547 ,  Y02P70/521

摘要： A solar cell module includes a plurality of solar cells each comprising a substrate, an emitter region placed at the substrate, and an anti-reflection region placed on the emitter region. The anti-reflection region includes a first opening region through which part of the emitter region is exposed and one or more second opening regions through which part of the emitter region is exposed. A first electrode is connected to the exposed emitter region of the first opening region through the anti-reflection region by metal plating and a first bus bar is connected to the exposed emitter region of one or more second opening regions through the anti-reflection region by metal plating.

摘要翻译： 太阳能电池模块包括多个太阳能电池，每个太阳能电池包括基板，放置在基板处的发射极区域和放置在发射极区域上的防反射区域。 防反射区域包括第一开口区域，发射区域的一部分被暴露出来，并且一个或多个第二开口区域通过该第一开口区域暴露出发射区域的一部分。 第一电极通过金属电镀通过抗反射区域连接到第一开口区域的暴露的发射极区域，并且第一汇流条通过反射区域通过反射区域连接到一个或多个第二开口区域的暴露的发射极区域， 金属电镀。