公开(公告)号：US20220233577A1

公开(公告)日：2022-07-28

申请号：US16761107

申请日：2018-11-03

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Molly Krisann Gibson ,  Nathan Wilson Stebbins ,  Ruth Thieroff-Ekerdt ,  Geoffrey A. von Maltzahn

IPC: A61K31/716 ,  A61K47/10 ,  A61K35/741 ,  A61P3/12

Abstract: Compositions, e.g., pharmaceutical compositions, nutritional compositions, medical foods, and food ingredients, as well as their methods of use, are provided, for treating diseases associated with hyperammonemia, e.g., urea cycle disorders (UCD) and hepatic encephalopathy (HE), e.g., minimal HE (MHE) and overt HE (OHE), and modulating enzyme activities and levels of microbes and taxa, and metabolites (e.g., ammonia) in the microbiome of a subject.

公开(公告)号：US20190290675A1

公开(公告)日：2019-09-26

申请号：US16466945

申请日：2017-12-06

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Molly Krisann Gibson ,  Christopher Matthew Liu ,  Geoffrey A. von Maltzahn ,  Han Yuan

IPC: A61K31/716 ,  A61K9/00 ,  A61P3/00

Abstract: Compositions of glycan polymers and methods of making and manufacturing the same are described herein. Also provided are methods of treating a disease or disorder with a glycan polymer preparation.