公开(公告)号：US11709165B2

公开(公告)日：2023-07-25

申请号：US16611947

申请日：2018-05-10

申请人： KAWASAKI GAKUEN EDUCATIONAL FOUNDATION

发明人： Mikio Oka ,  Eiichi Nakayama ,  Yoshihiro Ohue ,  Koji Kurose

IPC分类号： G01N33/68 ,  A61K39/00 ,  C07K14/82 ,  C12N5/0783 ,  G01N33/574 ,  A61K38/00 ,  A61P35/00

CPC分类号： G01N33/6854 ,  A61K39/001184 ,  A61P35/00 ,  C07K14/82 ,  C12N5/0636 ,  G01N33/57407 ,  A61K38/00 ,  A61K2039/892 ,  C12N2501/505 ,  G01N2800/344 ,  G01N2800/52

摘要： [Object] To provide a novel examination method for a cancer treatment effect, screening method for a peptide for a cancer vaccine, and peptide and composition for inducing an immune response against cancer. [Solving Means] Provided are an examination method for a cancer treatment effect and a screening method for a peptide for a cancer vaccine each including detecting an antibody against a cancer/testis antigen or an anti-p53 antibody in a sample. It is suitable that an anti-XAGE1 antibody (IgG and/or IgA) be detected, or an anti-NY-ESO-1 antibody (IgG) be detected. Also provided are a novel peptide and novel composition for inducing immune responses against cancer.