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公开(公告)号：US20230172579A1
公开(公告)日：2023-06-08
申请号：US17920220
申请日：2021-04-15
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Sujitkumar Hiwale , Biswaroop Chakrabarti , Deep Bera , Mark Thomas Johnson
CPC classification number: A61B8/08 , A61B8/4236
Abstract: The invention provides device for detecting potential sinus pathologies, comprising a patch (310), comprising one or more vibration sensing devices (320), configured to be placed on facial bones overlying a sinus of a subject, wherein the patch is configured to obtain facial bone vibration signals generated due to vibrations in facial bones surrounding the sinus, wherein characteristics of the facial bone vibration signals are representative of condition of the sinus. The device further comprises a processing subsystem operationally coupled to the patch and configured to: receive the facial bone vibration signals from the patch during vocalization of sounds by the subject, resulting in resonant frequency vibrations of the facial bones; and determine a physiological measure of the sinus of the subject based on characteristics of the facial bone vibration signals received during said vocalization of sounds by the subject, wherein the facial bone vibration signals comprise the resonant frequency vibrations.
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公开(公告)号：US20230352191A1
公开(公告)日：2023-11-02
申请号：US18140235
申请日：2023-04-27
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Murtaza Bulut , Mark Thomas Johnson , Biswaroop Chakrabarti , Wilbert Bouwman
Abstract: The invention relates to a computer-implemented method (600) of monitoring patient data. A patient record data source enables to access a patient record of a patient, wherein the patient record indicates a version of a medical protocol currently being used with the patient. A protocol data source indicates available versions of the medical protocol and/or of a medical guideline from which the medical protocol is derived. The used version of the medical protocol is compared to a further version of the medical protocol or of the medical guideline accessible via the protocol data source to obtain a change indicator for the used version of the medical protocol, and the change indicator is output.
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公开(公告)号：US11179117B2
公开(公告)日：2021-11-23
申请号：US16623476
申请日：2018-06-20
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Gereon Vogtmeier , Ravindra Bhat , Biswaroop Chakrabarti , Prasad Raghotham Venkat
Abstract: An apparatus (M) and related method for supporting X-ray imaging. The apparatus comprises an input interface (IN) for receiving a request to perform an X-ray exposure with an X-ray source (XR) of an X-ray imager (XI) to image an object (PAT). A compliance checker (CC) of the apparatus (M) is configured to check said request against an imaging safety protocol for said object to produce a safety compliance result. A safety enforcer (SE) of the apparatus is configured to issue, based on the safety compliance result, i) an alert signal and/or ii) a control signal to initiate a safety action that at least affect an impact of the requested X-ray exposure on the object.
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4.发明申请BIOLOGICAL CELL ASSESSMENT USING WHOLE GENOME SEQUENCE AND ONCOLOGICAL THERAPY PLANNING USING SAME 审中-公开使用全基因组序列和肿瘤治疗方法进行生物细胞评估公开(公告)号：US20140330162A1
公开(公告)日：2014-11-06
申请号：US14362508
申请日：2012-11-29
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Biswaroop Chakrabarti , Randeep Singh , Sunil Kamar
CPC classification number: C12Q1/6869 , A61B10/02 , G16B20/00 , G16B30/00
Abstract: A cancer test includes: processing a suspect tissue sample (10) acquired from a subject (6) to generate a suspect whole genome sequence (WGS) (20); processing a normal tissue sample (12) acquired from the subject to generate a normal WGS (22); computing a WGS comparison metric comparing the suspect WGS with the normal WGS; and identifying whether the suspect tissue sample comprises cancer tissue based on the computed WGS comparison metric. A tumor delineation method comprises: acquiring a plurality of probative tissue samples (104) from a subject (6) in or near a tumor (100); recording the sampling locations of the probative tissue samples; classifying each probative tissue sample respective to cancer based on genetic testing of the probative tissue sample; and delineating a boundary (110) of the tumor based on the classifications of the probative tissue samples and the recorded sampling locations.
Abstract translation: 癌症测试包括：处理从受试者（6）获得的可疑组织样品（10）以产生可疑全基因组序列（WGS）（20）; 处理从受试者获得的正常组织样本（12）以产生正常的WGS（22）; 计算将可疑WGS与正常WGS进行比较的WGS比较度量; 以及基于所计算的WGS比较度量来确定所述可疑组织样本是否包含癌组织。 肿瘤描绘方法包括：从肿瘤（100）中或附近的受试者（6）获取多个证明组织样本（104）; 记录证明组织样本的采样位置; 基于证实组织样本的遗传检测，将各自的癌症组织样本分类; 以及基于鉴别组织样本和记录的采样位置的分类来描绘肿瘤的边界（110）。
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公开(公告)号：US20230157614A1
公开(公告)日：2023-05-25
申请号：US17916594
申请日：2021-03-31
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Robertus Leonardus Maria in 't Groen , Gerardus Henricus Maria Gijsbers , Fei Zuo , Mark Johnson , Biswaroop Chakrabarti , Sujitkumar Hiwale , Deep Bera
CPC classification number: A61B5/33 , A61B8/54 , A61B5/28 , A61B8/42 , A61B8/0883
Abstract: A system (10) is for performing ECG measurements and comprises a probe (12) with an integrated one or more ECG electrodes (22) and an ultrasound sensing means (18), such as a transducer arrangement. The probe thus provides a mobile ECG electrode which can be sequentially moved between a set of different locations on the body for acquiring ECG measurements from different angles relative to the heart (i.e. different ‘leads’). Positioning of the probe in each required location is guided by a position guidance function which uses ultrasound data acquired by the ultrasound sensing means to locate the probe (with reference to an ultrasound body atlas (28) or map), and uses a stored set of reference body locations to guide a user with guidance information as to how to move the probe to arrive at a next target electrode location. In examples, the user may be guided through a sequence of electrode locations, with ECG data acquired at each one, thereby sequentially building up a set of standard ECG lead measurements.
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Patent Agency Ranking
公开(公告)号：US20220133230A1
公开(公告)日：2022-05-05
申请号：US17433485
申请日：2020-02-10
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Sujitkumar Sureshrao Hiwale , Deep Bera , Nico Maris Adriaan de Wild , Biswaroop Chakrabarti , Gerardus Henricus Maria Gijsbers , Ganesan Ramachandran , Mark Thomas Johnson
Abstract: An acoustic sensing apparatus and method are disclosed for acoustically surveying the chest area of a subject, and in particular the rib cage. In use the apparatus is placed on the chest, and it includes an arrangement of one or more sound sensors for sensing acoustic signals received from inside the chest. Based on the signal intensities picked up at a plurality of different locations across the chest, the different locations are each classified by a controller as either rib-aligned or intercostal space-aligned. The controller is further adapted to identify one or more sound intensity hotspots (42) within the signal intensity distribution to locate one or more anatomical objects or regions of interest within the chest, such as the heart mitral valve, the heart tricuspid valve, heart aortic valve, and the pulmonary artery as key areas for an auscultation procedure.
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公开(公告)号：US10751016B2
公开(公告)日：2020-08-25
申请号：US15774414
申请日：2016-11-02
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Stewart Young , Jens Von Berg , Daniel Bystrov , Nataly Wieberneit , Ulrich Neitzel , Pallavi Vajinepalli , Biswaroop Chakrabarti , Soubhik Paul
IPC: A61B6/00
Abstract: The quality of thoracic X-rays is depends on the inspiration state of an imaged patient. If the lungs of a patient are not significantly inflated during a thoracic X-ray, tissue from surrounding organs can cause the image to become cloudier, and the lung parenchyma is not effectively shown. Thus, there is a reliance on a medical professional to ensure that the patient is in an appropriate posture and inspiration state at the point of image exposure. This can be difficult with patients suffering from chronic conditions, though. Therefore, this application discusses a means to assess the inspiration state using the position of rib bones, and the diaphragm line in the X-ray image. Thus, an accurate estimate of inspiration state can automatically be reported to a medical professional, before a patient leaves the examination room, allowing an X-ray to be retaken, if necessary.
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8.发明申请POPULATION CLASSIFICATION OF GENETIC DATA SET USING TREE BASED SPATIAL DATA STRUCTURE 审中-公开使用基于树的空间数据结构对遗传数据进行群体分类公开(公告)号：US20150186596A1
公开(公告)日：2015-07-02
申请号：US14416647
申请日：2013-08-07
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Biswaroop Chakrabarti , Prakash Muniyappa , Sunil Kumar , Randeep Singh , Subodh Kumar , Ashwatha Matthur
IPC: G06F19/18
Abstract: Reference feature vectors are constructed representing refer-ence genetic data sets of a reference population. The reference feature vec-tors are transformed using a linear transformation to generate reduced di-mensionality vector representations of the reference genetic data sets of the reference population. A tree-based spatial data structure is constructed to index the reference genetic data sets as data points defined by at least some dimensions of the reduced dimensionality vector representations of the ref-erence genetic data sets of the reference population. The linear transform may be generated by performing feature reduction on the reference feature vectors. A feature vector representing a proband genetic data set is trans-formed using the linear transformation to generate a reduced-dimensional-ity vector representation that is located in the tree-based spatial data struc-ture to perform population assignment for the proband genetic data set.
Abstract translation: 参考特征向量被构建为参考群体的参考遗传数据集。 参考特征矢量使用线性变换来变换，以生成参考群的参考遗传数据集的减少的二维向量表示。 构建基于树的空间数据结构以将参考遗传数据集作为由参考群体的参考遗传数据集的缩减维度向量表示的至少一些维度定义的数据点进行索引。 可以通过对参考特征向量执行特征缩减来生成线性变换。 表示概率遗传数据集的特征向量使用线性变换来转换，以产生位于基于树的空间数据结构中的简化维度向量表示，以对先验遗传数据集执行群体分配 。
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公开(公告)号：US11191496B2
公开(公告)日：2021-12-07
申请号：US16623488
申请日：2018-06-26
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Biswaroop Chakrabarti , Prasad Raghotham Venkat , Ravindra Bhat , Gereon Vogtmeier
Abstract: An apparatus and related method for supporting X-ray imaging. The apparatus comprises an input interface (IN) for receiving an X-radiation scatter measurement obtained by an X-ray sensor (SXi) during operation of an X-ray imager (XI) for imaging a first object (PAT). A predictor component (PC) is configured to predict, based on said measurement, whether or not: i) a second object (P) is present, or ii) there is sufficient X-ray exposure of said first object (PAT). The apparatus comprises an output interface (OUT) for outputting a predictor signal indicative of an outcome of said prediction.
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公开(公告)号：US10607719B2
公开(公告)日：2020-03-31
申请号：US14363436
申请日：2012-12-03
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Sunil Kumar , Randeep Singh , Biswaroop Chakrabarti , Subodh Kumar
Abstract: A non-transitory storage medium stores an assembled genetic sequence comprising aligned sequencing reads. An electronic processing device is configured to perform operations including: identifying a possible variant in the assembled genetic sequence; computing value of at least one read property for reads of the assembled genetic sequence; and calling the possible variant conditional upon the computed values of the at least one read property for sequencing reads of the assembled genetic sequence that include the possible variant satisfying an acceptance criterion. The electronic processing device may be further configured to select at least one region of the assembled genetic sequence for validation based on a non random selection criterion.
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