公开(公告)号：US10806422B2

公开(公告)日：2020-10-20

申请号：US16097636

申请日：2017-05-24

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Roland Proksa ,  Daniela Muenzel

IPC: A61B6/00 ,  H05G1/20 ,  H05G1/08 ,  H01J35/04 ,  H01J35/06 ,  H01J35/08 ,  H05G1/58

Abstract: The present invention relates to an apparatus for generating X-rays. It is described to produce (210) with a power supply (30) a voltage. A cathode (22) of an X-ray source (20) is positioned (220) relative to an anode (24) of the X-ray source. Electrons are emitted (230) from the cathode. Electrons emitted from the cathode interact (240) with the anode with energies corresponding to the voltage. X-rays are generated (250) from the anode, wherein the electrons interact with the anode to generate the X-rays. The X-ray source is controlled (260), such that a plurality of first X-ray pulses is generated each having a first X-ray flux, wherein the first X-ray pulses are temporally separated from each other. The X-ray source is controlled (270), such that a least one second X-ray pulse is generated having a second X-ray flux that is substantially less than the first X-ray flux, wherein the at least one second X-ray pulse is generated temporally between consecutive pulses of the first X-ray pulses.

公开(公告)号：US11116465B2

公开(公告)日：2021-09-14

申请号：US15756602

申请日：2016-09-01

Applicant: KONINKLIJKE PHILIPS N.V. ,  TECHNISCHE UNIVERSITAET MUENCHEN

Inventor： Roland Proksa ,  Alexander André Fingerle ,  Daniela Muenzel ,  Franz Josef Pfeiffer ,  Thomas Koehler ,  Peter Benjamin Theodor Noel ,  Maximilian Von Teuffenbach ,  Julia Herzen ,  Konstantin Willer

IPC: A61B6/00 ,  A61B6/03

Abstract: A method of a virtual X-ray colonoscopy includes scanning (204) a dark-field contrast (144) insufflated colon lumen (140) with an X-ray scanner (110) configured for dark-field-contrast, which generates dark-field-contrasted projection data and attenuation projection data. The dark-field-contrasted projection data and the attenuation projection data are reconstructed (206) into one or more dark-field-contrasted images (148).

公开(公告)号：US10667769B2

公开(公告)日：2020-06-02

申请号：US15770773

申请日：2016-11-01

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Roland Proksa ,  Heiner Daerr ,  Daniela Muenzel ,  Peter Noel

IPC: G06K9/00 ,  A61B6/03 ,  A61B6/00

Abstract: The invention relates to a method of Computed Tomography imaging comprising: a. Performing a single acquisition of image data from at least two contrast agents into a blood vessel network, a first contrast agent among said at least two contrast agents having been in said blood vessel network for a longer time than a second contrast agent among said at least two contrast agents, b. Processing said image data using K-Edge detection and/or iodine delineation to separate data associated with each contrast agents in order to obtain a concentration map of each contrast agent, c. Determining from said image data a first part of the blood vessel network comprising both the first contrast agent and the second contrast agent, and a second part of the blood vessel network comprising only the first contrast agent, d. Calculating a partial blood volume map of the first part of the blood vessel network based on the total amount of second contrast agent and on the concentration map of the second contrast agent, e. Calculating a partial blood volume map of the second part of the blood vessel network based on the total amount of first contrast agent, on the concentration map of the first contrast agent and on the partial blood volume map of the first part of the blood vessel network.