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    VALVE STENT FOR INTRAVASCULAR REPERFUSION THERAPY
    1.
    发明公开
    VALVE STENT FOR INTRAVASCULAR REPERFUSION THERAPY 审中-公开

    公开(公告)号：US20240285407A1

    公开(公告)日：2024-08-29

    申请号：US18693487

    申请日：2022-09-19

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： James David CEZO ,  Arjen VAN DER HORST

    IPC: A61F2/24 ,  A61B8/04 ,  A61B8/06 ,  A61B8/12 ,  A61F2/48 ,  A61F2/95

    CPC classification number: A61F2/2476 ,  A61B8/04 ,  A61B8/06 ,  A61B8/12 ,  A61F2/2418 ,  A61F2/484 ,  A61F2002/9528 ,  A61F2250/001

    Abstract: A system includes a stent positionable within a coronary vein. The stent includes a valve and a stent body coupled to the valve and arranged to transition between a collapsed state and an expanded state. The system includes an intravascular reperfusion therapy device with a sensor and a catheter with a lumen shaped to receive the stent. The intravascular reperfusion therapy device delivers reperfusion therapy to a myocardium of a heart. The system includes a processor circuit that receives physiological data from the sensor, determines a progression of the reperfusion therapy, controls a configuration of the valve and/or the expansion state of the stent such that back pressure is controlled. With the stent in the expanded state, the stent body contacts a wall of the coronary vein and the valve obstructs blood flow in a first direction to generate the back pressure in an opposite, second direction.

    VALVED HANDLE ASSEMBLY HAVING A MOVABLE RING
    2.
    发明申请
    VALVED HANDLE ASSEMBLY HAVING A MOVABLE RING 有权

    公开(公告)号：US20210244930A1

    公开(公告)日：2021-08-12

    申请号：US17271223

    申请日：2019-09-06

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： Tyson REMM ,  Joseph Charles Pius GRIEBEL, JR. ,  James David CEZO ,  Adam TSCHIDA

    IPC: A61M39/02 ,  A61M39/06

    Abstract: The present disclosure discussed a device, method and/or system for performing a sealing control for a vascular treatment system having a handle assembly. To perform the sealing control, a movable ring associated with the handle assembly is adjusted to at least one of: a first position to provide a minimum pressure seal between the catheter and the handle assembly such that the catheter is freely movable within the handle assembly, a second position to provide a predetermined amount of pressure seal between the catheter and the handle assembly such that the catheter is movable in frictional contact with the handle assembly, and a third position to provide a maximum pressure seal between the catheter and the handle assembly such that the catheter is unmovable within the handle assembly.

    RENAL VASCULAR RESISTANCE USING INTRAVASCULAR BLOOD FLOW AND PRESSURE AND ASSOCIATED SYSTEMS, DEVICES, AND METHODS
    3.
    发明公开
    RENAL VASCULAR RESISTANCE USING INTRAVASCULAR BLOOD FLOW AND PRESSURE AND ASSOCIATED SYSTEMS, DEVICES, AND METHODS 审中-公开

    公开(公告)号：US20230233095A1

    公开(公告)日：2023-07-27

    申请号：US18099152

    申请日：2023-01-19

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： James David CEZO

    IPC: A61B5/026 ,  A61B5/0215 ,  A61B5/00 ,  G16H50/50 ,  G16H40/63

    CPC classification number: A61B5/026 ,  A61B5/02158 ,  A61B5/6852 ,  A61B5/742 ,  G16H50/50 ,  G16H40/63 ,  A61B2562/04 ,  A61B2562/0247

    Abstract: A system includes a processor circuit configured to receive a first set of data. The first set of data includes two pressure measurements and a flow measurement from the vasculature of a patient obtained while the sympathetic nervous system of the patient is not under stimulation. The processor circuit calculates a blood flow resistance value based on the first set of data. The processor circuit then receives a second set of data. The second set of data also includes two pressure measurements and a flow measurement from the vasculature of the patient obtained while the sympathetic nervous system of the patient is stimulated. The processor circuit calculates another blood resistance value based on the second set of data. The processor circuit then compares the two blood flow resistance values to determine whether a denervation procedure would be effective to mitigate the nerve system's response to stimulation. The processor circuit outputs to a screen display metrics obtained from the measurement procedure.

    ATHERECTOMY GUIDANCE THROUGH PHOTOACOUSTIC SIGNAL ANALYSIS
    4.
    发明公开
    ATHERECTOMY GUIDANCE THROUGH PHOTOACOUSTIC SIGNAL ANALYSIS 审中-公开

    公开(公告)号：US20230225793A1

    公开(公告)日：2023-07-20

    申请号：US18009127

    申请日：2021-06-15

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： Ramon Quido ERKAMP ,  Alvin CHEN ,  Shyam BHARAT ,  Mingxin ZHENG ,  Grzegorz Andrzej TOPOREK ,  James David CEZO

    IPC: A61B18/24

    CPC classification number: A61B18/24 ,  A61B2018/00577

    Abstract: Methods, Apparatuses, and Systems of operating a laser atherectomy system to perform an endoscopic atherectomy procedure within a vessel at a therapeutic region of an anatomical condition by use of an atherectomy laser device coupled to an ultrasound imaging probe. The atherectomy laser device operates to generate photoacoustic signals from a light source of the atherectomy laser device to for guidance within the vessel and to characterize tissue about the therapeutic region by delivery of pulsed wavelengths within the vessel, and to perform operations of tissue ablation directed to the anatomical condition. This enables guidance of the atherectomy laser device by feedback from the viewing of photoacoustic images based on photoacoustic signals generated the atherectomy laser device and created in response to changes in acoustic intensity due to changes of optical wavelength monitored by the ultrasound imaging probe.

    INTRAVASCULAR REPERFUSION THERAPY WITH AN EXPANDABLE STRUCTURE AND ASSOCIATED DEVICES, SYSTEMS, AND METHODS
    5.
    发明申请
    INTRAVASCULAR REPERFUSION THERAPY WITH AN EXPANDABLE STRUCTURE AND ASSOCIATED DEVICES, SYSTEMS, AND METHODS 有权

    公开(公告)号：US20240390009A1

    公开(公告)日：2024-11-28

    申请号：US18693339

    申请日：2022-09-20

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： James David CEZO ,  Arjen VAN DER HORST

    IPC: A61B17/12 ,  A61B17/00 ,  A61B90/00

    Abstract: A system includes an intravascular reperfusion therapy device positionable within a coronary vein to deliver reperfusion therapy to a myocardium of a heart. The intravascular reperfusion therapy device includes a catheter and a sensor. The catheter includes a plurality of arms configured to expand into the coronary vein to deliver the reperfusion therapy by obstructing blood flow in a first direction to generate back pressure in an opposite, second direction. The system includes a processor circuit that receives, from the sensor, physiological data associated with blood flow, determines, based on the physiological data, a progression of the reperfusion therapy, and controls, based on the progression of the reperfusion therapy, expansion of the plurality of arms while the intravascular reperfusion therapy device is positioned within the coronary vein such that the back pressure within the coronary vein is controlled.

    FLUID DELIVERY BASED INTRAVASCULAR REPERFUSION THERAPY DEVICES, SYSTEMS, AND METHODS
    8.
    发明申请
    FLUID DELIVERY BASED INTRAVASCULAR REPERFUSION THERAPY DEVICES, SYSTEMS, AND METHODS 有权

    公开(公告)号：US20240424284A1

    公开(公告)日：2024-12-26

    申请号：US18693622

    申请日：2022-09-14

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： James David CEZO ,  Arjen VAN DER HORST

    IPC: A61M60/523 ,  A61M60/104 ,  A61M60/32 ,  A61M60/531

    Abstract: A system includes an intravascular reperfusion therapy device configured to be positioned within a coronary vein of a patient to deliver reperfusion therapy to a myocardium of a heart associated with the coronary vein. The intravascular reperfusion therapy device includes a sensor, a pump, and a catheter with a lumen. The intravascular reperfusion therapy device is configured to, using the pump, direct flow of a fluid through the lumen to deliver the reperfusion therapy. The system includes a processor circuit configured to receive, from the sensor, physiological data associated with blood flow through the coronary vein, determine, based on the physiological data, a progression of the reperfusion therapy; and control, based on the progression of the reperfusion therapy, the flow of the fluid through the lumen such that the reperfusion therapy is controlled.

    BLOOD FLOW IN RENAL VASCULATURE USING ELECTRICAL RESISTANCE AND ASSOCIATED SYSTEMS, DEVICES, AND METHODS
    9.
    发明公开
    BLOOD FLOW IN RENAL VASCULATURE USING ELECTRICAL RESISTANCE AND ASSOCIATED SYSTEMS, DEVICES, AND METHODS 审中-公开

    公开(公告)号：US20230277076A1

    公开(公告)日：2023-09-07

    申请号：US18098364

    申请日：2023-01-18

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： James David CEZO

    IPC: A61B5/027 ,  A61B5/00

    CPC classification number: A61B5/027 ,  A61B5/742 ,  A61B5/6876

    Abstract: A system includes an endovascular catheter or guidewire that is positioned within a blood vessel. The catheter or guidewire includes two pairs of electrodes. One pair of electrodes is in communication with a power source. The other pair of electrodes is in communication with an amplifier and/or rectifier. The system also includes a processor circuit configured for communication with the endovascular catheter or guidewire. The processor circuit controls one pair of electrodes to provide a constant electrical current from one electrode to another. The processor circuit controls the other pair of electrodes to measure a voltage difference. The processor circuit then determines, based on the voltage difference, a blood flow metric of the blood within the blood vessel and outputs the blood flow metric to a display.

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