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公开(公告)号：US20200033305A1
公开(公告)日：2020-01-30
申请号：US16495156
申请日：2018-03-20
IPC分类号： G01N30/60 , G01N33/00 , G01N33/497
摘要： A 3D gas chromatography (GC) column development is possible by assembly of two parts each being substrates formed by gas tight materials. One part may be a silicon substrate with a snake shaped flow channel structure and the other part may be a glass plate. Both are coated with a column packing comprising polubutadiene, which is also able to glue or bond both parts together, thereby sealing the flow channel, thus forming a GC column. The column packaging can be composed in all kinds of polarity from very hydrophobic till very hydrophilic. In this way the column packing can be tuned on resolution for particular molecules which are interesting to detect, e.g. Octane. The invention is advantageous for micro GC columns.
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公开(公告)号：US20190133553A1
公开(公告)日：2019-05-09
申请号：US16095422
申请日：2017-04-26
发明人： Harm Jan Willem BELT , Franciscus Johannes Gerardus HAKKENS , Godefridus Antonius HARKS , Gerardus Henricus Maria GIJSBERS , Kevin Grayson WICKLINE , Lucas Johannes Anna Maria BECKERS
摘要： An ultrasound device (10) is disclosed comprising a transducer arrangement (110) and an acoustically transmissive window (150) over said arrangement, said window comprising an elastomer layer (153) having conductive particles dispersed in the elastomer, the elastomer layer having a pressure-sensitive conductivity, the ultrasound device further comprising an electrode arrangement (160) coupled to said elastomer layer and adapted to measure said pressure-sensitive conductivity. An ultrasound system and arrangement including such an ultrasound device are also disclosed.
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公开(公告)号：US20240197288A1
公开(公告)日：2024-06-20
申请号：US18393832
申请日：2023-12-22
发明人： Franciscus Johannes Gerardus HAKKENS , Lucas Johannes Anna Maria BECKERS , Johannes Wilhelmus WEEKAMP , Peter DIRKSEN , Petrus Henricus Maria TIMMERMANS , Sergei Y. SHULEPOV , Hans-Peter LOEBL
CPC分类号： A61B8/12 , A61B8/445 , A61B8/4477 , A61B8/4494 , G01S7/52085 , G01S15/8906
摘要： An intraluminal ultrasound imaging device includes a flexible elongate member configured to be positioned within a body lumen of a patient. An ultrasound imaging assembly is disposed at the distal portion of the flexible elongate member. The ultrasound imaging assembly includes a plurality of acoustic elements and an acoustically-transparent window disposed over the plurality of acoustic elements. The acoustically-transparent window comprising a plurality of layers formed on top of one another. The plurality of layers includes an innermost layer directly contacting the plurality of acoustic elements, an outermost layer opposite the innermost layer, and an adhesive layer. The outermost layer includes a tubing. A hardness of the innermost layer is less than hardnesses of every other layer of the plurality of layers. A hardness of the outermost layer is greater than the hardnesses of every other layer of the plurality of layers.
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公开(公告)号：US20180116546A1
公开(公告)日：2018-05-03
申请号：US15572850
申请日：2016-05-17
发明人： Sander Theodoor PASTOOR , Lucas Johannes Anna Maria BECKERS , Timon Rutger GROB , Denny MATHEW , Edward Theodorus Maria BERBEN
IPC分类号： A61B5/053 , A61B5/0408 , A61B5/0416 , A61B5/0478
摘要： An electrode configured to provide electrical contact with skin of a subject is provided. The electrode includes an electrode body configured to be removably coupled with the skin of the subject and to receive electrical signals from and/or transmit electrical signals to the skin of the subject, and an electrical coupling that facilitates coupling the electrode to an external computing system. The electrode body includes a conductive silicone material configured to enable uptake or diffusion of moisture from the skin of the subject over which the electrode body is disposed; and a detergent configured to facilitate a flow of ions through the conductive silicone material.
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公开(公告)号：US20220380722A1
公开(公告)日：2022-12-01
申请号：US17762396
申请日：2020-09-24
IPC分类号： C12N5/00
摘要： A material for culturing cells is disclosed. The material contains a bulk-modified elastomer having a Shore hardness (DIN EN ISO 868) in a range of Shore00 20 to Shore A 80 and comprising a plurality of fatty acid moieties covalently bound to the elastomer bulk, wherein the carboxylic acid groups of said moieties are available on an external surface of said material to provide said binding, and wherein the bulk-modified elastomer is obtained by forming a composition comprising a vinyl-functionalized or a hydride-functionalized elastomer or at least one precursor thereof, a free of saponified unsaturated fatty acid in a range of 0.5-5% by weight of the total weight of the a vinyl-functionalized or a hydride-functionalized elastomer or at least one precursor thereof and a cross-linking catalyst in a mold having a polar inner surface; and bulk-modifying the vinyl-functionalized or the hydride-functionalized elastomer by covalently binding the free or saponified unsaturated fatty acid to the elastomer bulk in said mold by a cross-linking reaction between a vinyl group or a hydride group of the elastomer and an unsaturated carbon-carbon bond of the unsaturated fatty acid to obtain the material. Also disclosed are a fluidic device module and fluidic device, a cell culturing method and a drug testing method.
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公开(公告)号：US20210128107A1
公开(公告)日：2021-05-06
申请号：US17256248
申请日：2019-06-28
发明人： Franciscus Johannes Gerardus HAKKENS , Lucas Johannes Anna Maria BECKERS , Johannes Wilhelmus WEEKAMP , Peter DIRKSEN , Petrus Henricus Maria TIMMERMANS , Sergei Y. SHULEPOV , Hans-Peter LOEBL
摘要： An intraluminal ultrasound imaging device includes a flexible elongate member configured to be positioned within a body lumen of a patient. An ultrasound imaging assembly is disposed at the distal portion of the flexible elongate member. The ultrasound imaging assembly includes a plurality of acoustic elements and an acoustically-transparent window disposed over the plurality of acoustic elements. The acoustically-transparent window comprising a plurality of layers formed on top of one another. The plurality of layers includes an innermost layer directly contacting the plurality of acoustic elements, an outermost layer opposite the innermost layer, and an adhesive layer. The outermost layer includes a tubing. A hardness of the innermost layer is less than hardnesses of every other layer of the plurality of layers. A hardness of the outermost layer is greater than the hardnesses of every other layer of the plurality of layers.
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