公开(公告)号：US11319360B2

公开(公告)日：2022-05-03

申请号：US16475052

申请日：2017-12-29

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Eun-ee Koh ,  Eun Jung Lee ,  Yoo Soo Yang ,  In-San Kim

IPC: C07K14/71 ,  A61P35/00 ,  C12N9/12 ,  A61K38/00

Abstract: The present invention provides a recombinant exosome and uses thereof. More particularly, the present invention provides a recombinant exosome wherein a phagocytosis promoting protein is presented on the surface thereof.

公开(公告)号：US20190216947A1

公开(公告)日：2019-07-18

申请号：US16247937

申请日：2019-01-15

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Gi Hoon NAM ,  Eun Jung Lee ,  Yoo Soo Yang ,  Cherl Hyun Jeong ,  In-San Kim ,  Kwangmeyung Kim

IPC: A61K47/69 ,  B82Y5/00 ,  C07K16/28 ,  B82Y40/00 ,  A61K31/704 ,  A61P35/00 ,  C07K14/785 ,  C07K14/79 ,  C07K14/705 ,  C07K14/005 ,  A61K31/337

CPC classification number: A61K47/6929 ,  A61K9/51 ,  A61K31/337 ,  A61K31/69 ,  A61K31/704 ,  A61K39/395 ,  A61P35/00 ,  B82Y5/00 ,  B82Y40/00 ,  C07K14/005 ,  C07K14/47 ,  C07K14/70546 ,  C07K14/785 ,  C07K14/79 ,  C07K16/2818

Abstract: The present invention relates to a novel recombinant nanocage and use thereof wherein the nanocage is formed by self-assembly of a fusion protein including a phagocytosis enhancing protein and a self-assembling protein, and to a protein nanocage complex in which an immunogenic cell death inducer is loaded in the nanocage as an active ingredient.

公开(公告)号：US10905774B2

公开(公告)日：2021-02-02

申请号：US16247937

申请日：2019-01-15

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Gi Hoon Nam ,  Eun Jung Lee ,  Yoo Soo Yang ,  Cherl Hyun Jeong ,  In-San Kim ,  Kwangmeyung Kim

IPC: A61K39/00 ,  A61K47/00 ,  A61K9/14 ,  A61K39/12 ,  A61K47/69 ,  A61K31/704 ,  C07K14/79 ,  C07K14/47 ,  A61K31/69 ,  A61K9/51 ,  A61K39/395 ,  A61P35/00 ,  A61K31/337 ,  B82Y5/00 ,  B82Y40/00 ,  C07K14/005 ,  C07K14/705 ,  C07K14/785 ,  C07K16/28

Abstract: The present invention relates to a novel recombinant nanocage and use thereof wherein the nanocage is formed by self-assembly of a fusion protein including a phagocytosis enhancing protein and a self-assembling protein, and to a protein nanocage complex in which an immunogenic cell death inducer is loaded in the nanocage as an active ingredient.