公开(公告)号：US20200016269A1

公开(公告)日：2020-01-16

申请号：US16395236

申请日：2019-04-26

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sehoon KIM ,  Youngsun KIM ,  Keunsoo JEONG ,  Gayoung KIM

IPC: A61K41/00 ,  C09B23/08 ,  C09B67/46 ,  C09B67/02 ,  C09B67/54 ,  A61N5/06

Abstract: The present invention relates to near-infrared-absorbing dye-based composite particles which exhibit a photothermal effect and/or photoacoustic signal upon photoirradiation, a preparation method thereof, and a use thereof. The near-infrared-absorbing composite particles comprise: a water-insoluble salt of a near-infrared-absorbing dye, which comprises anions of the near-infrared-absorbing dye and metal cations capable of forming a precipitation product with the anions of the near-infrared-absorbing dye; and particles of a polymeric surfactant, in which a water-insoluble salt of the near-infrared-absorbing dye is supported in the hydrophobic part of the polymeric surfactant.