公开(公告)号：US20230406812A1

公开(公告)日：2023-12-21

申请号：US18036847

申请日：2021-11-12

Applicant: INSTITUTE FOR BASIC SCIENCE ,  KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Chang Jun LEE ,  Heejung CHUN ,  Woojin WON ,  Ki Duk PARK ,  Jong Hyun PARK ,  Ae Nim PAE ,  Ji Won CHOI ,  Elijah LEE ,  Sun Jun PARK ,  Hyeon Jeong KIM ,  Yoowon KIM ,  Byung Eun KIM ,  Siwon KIM

IPC: C07C211/53 ,  A23L33/10 ,  A61P25/28

CPC classification number: C07C211/53 ,  A61P25/28 ,  A23L33/10

Abstract: The present invention provides a novel aminoaromatic compound or a pharmaceutically acceptable salt thereof, a pharmaceutical composition that is for preventing or treating neurodegenerative diseases and comprises same as an active ingredient, and a health functional food composition for preventing or ameliorating neurodegenerative diseases.

公开(公告)号：US20210317083A1

公开(公告)日：2021-10-14

申请号：US17268958

申请日：2019-08-19

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Ki Duk PARK ,  Ae Nim PAE ,  Sang Min LIM ,  Jong Hyun PARK ,  Ji Won CHOI ,  Siwon KIM ,  Hyeon Jeong KIM ,  Seul Ki YEON

IPC: C07D213/52 ,  C07F9/40

Abstract: The present invention relates to a novel halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative or a pharmaceutically acceptable salt thereof; a preparation method thereof; and an Nrf2 activator and a pharmaceutical composition for preventing or treating diseases induced by a decrease in Nrf2 activity, both of which comprise the same as an active ingredient.