公开(公告)号：US11241517B2

公开(公告)日：2022-02-08

申请号：US16165515

申请日：2018-10-19

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sang Heon Kim ,  Joo Young Lee ,  Seung Ja Oh

IPC: A61L27/24 ,  B33Y70/00 ,  B29C64/40 ,  A61L27/20 ,  A61L27/22 ,  A61L27/26 ,  A61L27/38 ,  A61L27/52 ,  B33Y10/00 ,  B29K105/00

Abstract: Provided are a hydrogel composition with high viscoelasticity and a bioink composition including the hydrogel composition. The hydrogel composition according to an embodiment is composed of natural biocompatible substances and thus is not toxic, but has high viscosity, resulting in high mechanical stability or long persistence. Thus, the hydrogel composition may be usefully utilized as a bioink composition for bioprinting, a support in tissue engineering, or a soft tissue filler.

公开(公告)号：US09682113B2

公开(公告)日：2017-06-20

申请号：US15132899

申请日：2016-04-19

Applicant: Korea Institute of Science and Technology

Inventor： Sang Hoon Jung ,  Kyung A Kim ,  Suk-Woo Kang ,  Joo Young Lee ,  Hong Ryul Ahn ,  Youngwoo Song

IPC: A61K36/44 ,  A61K9/00 ,  A23L1/30 ,  A23L33/105

CPC classification number: A61K36/44 ,  A23L33/105 ,  A61K9/0053

Abstract: Disclosed is a method for preventing, improving and/or treating cornea damage or a corneal disease, including administering an effective amount of an extract of a persimmon tree for preventing, improving or treating cornea damage to a subject in need thereof. The extract may be a persimmon leaf extract and the extract is effective in suppressing inflammation of the cornea and protecting corneal cells.