公开(公告)号：US11359096B2

公开(公告)日：2022-06-14

申请号：US16403041

申请日：2019-05-03

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jun-Seok Lee ,  Dhiraj P. Murale ,  Seong-Cheol Hong ,  Kyung-Tae Hong ,  Yun-Kyung Kim ,  Seok Lee

IPC: C09B23/04 ,  G01N21/64 ,  C07F5/02

Abstract: Disclosed is a fluorescent probe specifically labeling mitochondria, which can exhibit high transmittance by virtue of light emission in the NIR range and in which nonspecific fluorescence absorption in biomolecules can be avoided, making it possible to observe fluorescence images in deep tissue.

公开(公告)号：US10100065B2

公开(公告)日：2018-10-16

申请号：US15479150

申请日：2017-04-04

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jun-Seok Lee ,  Dhiraj P. Murale ,  Seong-Cheol Hong ,  Seok Lee

IPC: C07F5/02 ,  C09B69/00 ,  C07F9/6561 ,  C09K11/06 ,  G01N33/58

Abstract: This invention relates to a compound for labeling mitochondria and a method of producing the same, wherein the compound is represented by Chemical Formula 1 or Chemical Formula 2 below, and is useful in labeling mitochondria. In Chemical Formulas 1 and 2, n is 4 or 10.

公开(公告)号：US09650660B2

公开(公告)日：2017-05-16

申请号：US15084925

申请日：2016-03-30

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Min-Ah Seo ,  Dong-Kyu Lee ,  Jun-Seok Lee ,  Jae-Hun Kim ,  Chul-Ki Kim ,  Taik-Jin Lee ,  Seok Lee ,  Young-Min Jhon

IPC: G01N33/569 ,  C12Q1/02 ,  G01N21/59 ,  G01N21/63

CPC classification number: G01N21/59 ,  C12Q1/04 ,  G01N21/3581 ,  G01N21/63 ,  G01N33/56983 ,  G01N2333/11

Abstract: Disclosed herein are a method and device for sensing avian influenza viruses, using terahertz electromagnetic waves. By the method, even a trace amount of avian influenza viruses in a liquid state can be accurately discriminated and sensed, with high sensitivity and selectivity, using a sensing chip that works in a terahertz electromagnetic wave band. Using the method, avian influenza viruses even at low concentrations can be accurately analyzed with high sensitivity and selectivity in which terahertz electromagnetic waves are irradiated onto avian influenza viruses through a sensing chip having a meta unit in which a pattern is formed to amplify a frequency corresponding to an absorption frequency of an avian influenza virus of interest.