公开(公告)号：US20180105852A1

公开(公告)日：2018-04-19

申请号：US15444605

申请日：2017-02-28

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Dae Ro AHN ,  Kyoung Ran KIM

IPC: C12P19/34 ,  C12N15/87 ,  C12N15/115

Abstract: Provided is a method of preparing nanoparticle-type polynucleotides, the method comprising forming the polynucleotides comprising modified nucleotides, in which the forming includes chemically synthesizing the polynucleotides comprising modified nucleotides, synthesizing the polynucleotides comprising modified nucleotides using an enzyme, or a combination thereof.

公开(公告)号：US20160051483A1

公开(公告)日：2016-02-25

申请号：US14803343

申请日：2015-07-20

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Dae Ro AHN ,  Se Hoon KIM ,  Kyoung Ran KIM ,  Hyo Young KIM ,  Yong Deok LEE

IPC: A61K9/51 ,  A61K49/00 ,  A61K38/02 ,  A61K31/713 ,  A61K31/7088

CPC classification number: A61K9/513 ,  A61K9/0019 ,  A61K31/704 ,  A61K31/7088 ,  A61K31/713 ,  A61K38/02 ,  A61K47/549 ,  A61K49/0002 ,  A61K49/0032 ,  A61K49/0043 ,  A61K49/0054

Abstract: The present invention relates to a molecule delivery technology and a carrier technology, which may selectively deliver a material to a desired specific cell and living tissue. The present invention may be utilized in the field of a drug carrier which effectively delivers an imaging probe and a therapeutic agent to an affected part.

Abstract translation: 本发明涉及分子递送技术和载体技术，其可以选择性地将材料递送到期望的特定细胞和活组织。 本发明可以用于有效地将成像探针和治疗剂输送到患部的药物载体领域。