公开(公告)号：US20150336938A1

公开(公告)日：2015-11-26

申请号：US14760400

申请日：2014-01-28

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jungyeob HAM ,  Tae Jung KIM ,  Hak Cheol KWON ,  Kyu Hyuk JEONG ,  Jungho SONG ,  Bong Chul CHUNG

IPC: C07D407/04 ,  C07D405/04 ,  C07D493/04 ,  C07D307/88 ,  C07D409/04

CPC classification number: C07D307/88 ,  C07D405/04 ,  C07D407/04 ,  C07D409/04 ,  C07D493/04

Abstract: The present disclosure relates to a novel method for preparing an arylnaphthalene lignan compound. In synthesis of arylnaphthalene lignan compounds and derivatives according to the present disclosure, a naphthalene backbone may be constructed first and an aryl group may be introduced at the final stage. Through this, various kinds of derivatives that could not be prepared from the existing methods can be synthesized effectively. Further, the synthesis method according to the present disclosure is appropriate for large-scale production.

Abstract translation: 本公开涉及一种制备芳基萘酚化合物的新方法。 在根据本公开的芳基萘木酚素化合物和衍生物的合成中，可以首先构建萘主链，并且可以在最后阶段引入芳基。 通过这种方法，可以有效地合成不能用现有方法准备的各种衍生物。 此外，根据本公开的合成方法适用于大规模生产。