公开(公告)号：US20180344489A1

公开(公告)日：2018-12-06

申请号：US15716620

申请日：2017-09-27

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Soo Hyun KIM ,  Young Mee JUNG ,  Seung Hyuk IM

IPC: A61F2/91 ,  A61L31/14 ,  A61L31/06

Abstract: A biodegradable stent and a method for preparing the same, which more particularly relate to a technology of preparing a biodegradable stent with improved flexibility and mechanical strength. The method includes a step of solid-state drawing a biodegradable filament and a step of shaping and then annealing the drawn biodegradable filament.

公开(公告)号：US20210269602A1

公开(公告)日：2021-09-02

申请号：US17095925

申请日：2020-11-12

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Soo Hyun KIM ,  Youngmee JUNG ,  Justin Jihong CHUNG ,  Seung Hyuk IM

IPC: C08J3/03 ,  A61K9/107 ,  A61K47/34

Abstract: Provided are a method for producing a stereocomplex polylactic acid composite based on oil-in-water emulsion blending, a method for preparing a drug delivery composition using a stereocomplex polylactic acid composite produced by the production method, and a drug delivery composition prepared by the preparation method. The stereocomplex polylactic acid composite is produced using oil-in-water emulsion blending that has the advantages of simple process, short production time, and high stereocomplexation efficiency compared to existing methods such as solution blending, melt-blending, and supercritical fluid technology. In addition, the drug delivery composition is prepared using oil-in-water emulsion blending that allows the drug to be loaded into the polymer chains of the stereocomplex polylactic acid in a very easy and efficient manner and facilitates release of the drug at room temperature over a long period of time.

公开(公告)号：US20180179331A1

公开(公告)日：2018-06-28

申请号：US15717212

申请日：2017-09-27

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Soo Hyun KIM ,  Young Mee JUNG ,  Seung Hyuk IM

IPC: C08G63/08

CPC classification number: C08G63/08 ,  G01N25/4866

Abstract: Disclosed is a method for preparing a poly(L-lactic acid) composite. According to the method, PLLA can be processed without losing its physical properties during thermal processing and can be effectively used to manufacture a final product with improved thermal properties. In addition, the monomer is not thermally decomposed during high-temperature polymerization. Therefore, the poly(L-lactic acid) composite can be prevented from browning. Also disclosed is a poly(L-lactic acid) composite prepared by the method.