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公开(公告)号：US20190321455A1
公开(公告)日：2019-10-24
申请号：US16283121
申请日：2019-02-22
Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY , MEDICINAL BIOCONVERGENCE RESEARCH CENTER
Inventor： Myung Hee Kim , Eun Young Lee , Sung Hoon Kim , Chul Ho Lee
Abstract: The present invention relates to an EPRS (glutamyl-prolyl-tRNA synthetase) protein or a fragment thereof.The EPRS protein of the present invention or fragment thereof may bind to PCBP2 protein to activate the MAVS signaling pathway, and thus it has anti-RNA viral effects, thereby being effective for preventing or treating a RNA viral infectious disease.
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公开(公告)号：US11173192B2
公开(公告)日：2021-11-16
申请号：US16283121
申请日：2019-02-22
Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY , MEDICINAL BIOCONVERGENCE RESEARCH CENTER
Inventor： Myung Hee Kim , Eun Young Lee , Sung Hoon Kim , Chul Ho Lee
Abstract: The present invention relates to an EPRS (glutamyl-prolyl-tRNA synthetase) protein or a fragment thereof.
The EPRS protein of the present invention or fragment thereof may bind to PCBP2 protein to activate the MAVS signaling pathway, and thus it has anti-RNA viral effects, thereby being effective for preventing or treating a RNA viral infectious disease.-
公开(公告)号：US10695390B2
公开(公告)日：2020-06-30
申请号：US16060780
申请日：2016-12-09
Inventor： Chul Ho Lee , Yong-Hoon Kim , Jung Ran Noh , Dong Hui Choi , Jung Hwan Hwang , Kyoung Shim Kim , Yun-Jung Seo , In-Bok Lee , Jung-Hyeon Choi
IPC: A61K36/428 , A61K36/42 , A23K10/30 , A23L33/105 , A61P1/16
Abstract: The present invention relates to: a composition comprising a Sicyos angulatus extract or a fraction thereof as an effective ingredient for preventing, alleviating, or treating liver diseases; and a method for preventing or treating liver diseases, comprising a step of administering the composition to a subject suspected of having a liver disease.
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