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公开(公告)号：US11738063B2
公开(公告)日：2023-08-29
申请号：US17012238
申请日：2020-09-04
Inventor： Won Gon Kim , Baek Soo Han , Jeong Su Byun , Ha Young Choi
Abstract: The present invention relates to a pharmaceutical composition and health functional food for preventing or treating neurodegenerative diseases which include a flower extract of Daphne genkwa or fractions thereof as an active ingredient. The pharmaceutical composition and health functional food for preventing or treating neurodegenerative diseases are, not like extracts from stems and/or roots of Daphne genkwa, free from genotoxicity and have superior prophylactic or treatment effects against neurodegenerative diseases.
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公开(公告)号：US12226395B2
公开(公告)日：2025-02-18
申请号：US17811327
申请日：2022-07-08
Inventor： Won Gon Kim , Baek Soo Han , Jeong Su Byun , Van Minh Nguyen , Ha Young Choi
IPC: A61K31/36 , A23L33/105 , A61K31/232
Abstract: The present invention relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases comprising a diterpene, or a pharmaceutically acceptable salt thereof. Specifically, the diterpene of the present invention can prevent or treat neurodegenerative diseases caused by inhibition of Nurr1 activity by activating Nurr1 and inhibiting the inflammatory response.
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公开(公告)号：US10792323B2
公开(公告)日：2020-10-06
申请号：US16349762
申请日：2017-11-13
Inventor： Won Gon Kim , Baek Soo Han , Jeong Su Byun , Ha Young Choi
Abstract: The present invention relates to a pharmaceutical composition and health functional food for preventing or treating neurodegenerative diseases which include a flower extract of Daphne genkwa or fractions thereof as an active ingredient. The pharmaceutical composition and health functional food for preventing or treating neurodegenerative diseases are, not like extracts from stems and/or roots of Daphne genkwa, free from genotoxicity and have superior prophylactic or treatment effects against neurodegenerative diseases.
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