公开(公告)号：US12226395B2

公开(公告)日：2025-02-18

申请号：US17811327

申请日：2022-07-08

Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

Inventor： Won Gon Kim ,  Baek Soo Han ,  Jeong Su Byun ,  Van Minh Nguyen ,  Ha Young Choi

IPC: A61K31/36 ,  A23L33/105 ,  A61K31/232

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases comprising a diterpene, or a pharmaceutically acceptable salt thereof. Specifically, the diterpene of the present invention can prevent or treat neurodegenerative diseases caused by inhibition of Nurr1 activity by activating Nurr1 and inhibiting the inflammatory response.