公开(公告)号：US20250027095A1

公开(公告)日：2025-01-23

申请号：US18776896

申请日：2024-07-18

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Ju Young LEE ,  Mi Ri KIM ,  Myung Hyun NOH ,  Soo Young MOON

IPC: C12N15/70 ,  C07K14/47 ,  C12N1/20 ,  C12N9/22 ,  C12N15/113

Abstract: Disclosed are a plasmid comprising dxCas9 and a CRP derivative for controlling the expression of a target gene, a recombinant strain transformed with the plasmid, a preparation method therefor, a target gene control system, and a method for controlling the expression of a target gene, wherein the plasmid, recombinant strain, and expression control system according to the present invention can improve the production of high-value-added substances by construction of a system for simultaneously and multiply controlling the expression of target genes.