公开(公告)号：US20140209475A1

公开(公告)日：2014-07-31

申请号：US14189552

申请日：2014-02-25

Applicant: Korea University Research and Business Foundation

Inventor： Young Keun KIM ,  Jee-Won LEE ,  Jin-Seung PARK ,  Moon Kyu CHO ,  Eun Jung LEE

IPC: G01N27/327 ,  C25D5/02

CPC classification number: G01N27/327 ,  B82Y30/00 ,  C07K14/005 ,  C07K14/31 ,  C12N2730/10122 ,  C12N2740/16122 ,  C25D5/022

Abstract: There is provided a nanohair structure with the nanowires exposed on a nanotemplate; the method thereof; and a three-dimensional nanostructure-based sensor with ultra-sensitivity and greatly increased three-dimensional surface-to-volume ratio which immobilizes bio-nanoparticles to the nanohair structure and arranges antibodies to the nano surface with the controlled orientation by physical interaction.

Abstract translation: 提供纳米线结构，纳米线暴露在纳米模板上; 其方法; 以及具有超灵敏度和大大提高的三维表面体积比的三维纳米结构传感器，其将生物纳米颗粒固定到纳米结构结构，并通过物理相互作用以受控的取向将抗体排列到纳米表面。

公开(公告)号：US20160349250A1

公开(公告)日：2016-12-01

申请号：US15152259

申请日：2016-05-11

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Jeewon LEE ,  Eun Jung LEE ,  Jong Hwan LEE

IPC: G01N33/543 ,  G01N33/58

CPC classification number: G01N33/54346 ,  G01N33/56988 ,  G01N33/582 ,  G01N2333/155

Abstract: The present invention relates to a use of a protein nanoparticle-based hydrogel, and more particularly, to a use of a protein nanoparticle-based hydrogel capable of highly sensitive and simultaneous multi-detection of disease markers by using a hydrogel within which protein nanoparticles presenting multiple copies of disease marker detection probes are immobilized.

Abstract translation: 本发明涉及蛋白质纳米颗粒型水凝胶的使用，更具体地，涉及使用蛋白质纳米颗粒型水凝胶，其能够通过使用其中蛋白质纳米粒子呈现的水凝胶来高度灵敏和同时多重检测疾病标记物 疾病标记物检测探针的多个拷贝被固定化。

公开(公告)号：US20140134601A1

公开(公告)日：2014-05-15

申请号：US13938575

申请日：2013-07-10

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Jee Won LEE ,  Eun Jung LEE ,  Jong Hwan LEE

IPC: G01N33/543 ,  G01N33/569

CPC classification number: G01N33/54346 ,  G01N33/56988

Abstract: The present invention relates to a use of a protein nanoparticle-based hydrogel, and more particularly, to a use of a protein nanoparticle-based hydrogel capable of highly sensitive and simultaneous multi-detection of disease markers by using a hydrogel to which a protein nanoparticle representing a disease marker detection probe is immobilized.

Abstract translation: 本发明涉及蛋白质纳米颗粒型水凝胶的用途，更具体地说，涉及使用蛋白质纳米颗粒型水凝胶，其能够通过使用蛋白质纳米颗粒的水凝胶来高度灵敏和同时多重检测疾病标记物 代表疾病标记检测探针被固定。