公开(公告)号：US20240209327A1

公开(公告)日：2024-06-27

申请号：US18288728

申请日：2022-04-15

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Jee Won LEE ,  Yeon Hwa YU ,  Yoo Bin CHOI

IPC: C12N9/02 ,  C07K14/47 ,  C12P7/04 ,  C12P7/16

CPC classification number: C12N9/0073 ,  C07K14/47 ,  C12N9/0083 ,  C12P7/04 ,  C12P7/16 ,  C12Y114/99039

Abstract: The present invention relates to: a protein having activity for producing methanol or butanol by oxidizing methane or butanol; a microorganism expressing same; a composition for producing methanol or butanol using same; and a method for producing methanol or butanol, wherein the protein is a self-assembled protein comprising a ferritin monomer fused with an ammonia oxidase active domain having methane oxidation activity, or a butane oxidase active domain having butane oxidation activity.

公开(公告)号：US20240376443A1

公开(公告)日：2024-11-14

申请号：US18288490

申请日：2022-04-15

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Jee Won LEE ,  Yeon Hwa YU ,  Yoo Bin CHOI

IPC: C12N9/02 ,  C07K14/47 ,  C12P7/04

Abstract: The present invention relates to a protein including self-assembled ferritin monomers, in which a methane oxidation active domain, and an electron transfer domain including a flavin adenine dinucleotide (FAD)-binding domain are fused, and to: a protein which can oxidize methane by using NADH in vivo as a reducing agent, thus being capable of oxidizing methane to methanol without using a separate reducing agent; a microorganism expressing the same; a composition for producing methanol by using the same; and a method for producing methanol.

公开(公告)号：US20140134601A1

公开(公告)日：2014-05-15

申请号：US13938575

申请日：2013-07-10

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Jee Won LEE ,  Eun Jung LEE ,  Jong Hwan LEE

IPC: G01N33/543 ,  G01N33/569

CPC classification number: G01N33/54346 ,  G01N33/56988

Abstract: The present invention relates to a use of a protein nanoparticle-based hydrogel, and more particularly, to a use of a protein nanoparticle-based hydrogel capable of highly sensitive and simultaneous multi-detection of disease markers by using a hydrogel to which a protein nanoparticle representing a disease marker detection probe is immobilized.

Abstract translation: 本发明涉及蛋白质纳米颗粒型水凝胶的用途，更具体地说，涉及使用蛋白质纳米颗粒型水凝胶，其能够通过使用蛋白质纳米颗粒的水凝胶来高度灵敏和同时多重检测疾病标记物 代表疾病标记检测探针被固定。