公开(公告)号：US20170246115A1

公开(公告)日：2017-08-31

申请号：US15290387

申请日：2016-10-11

Applicant: KOWA COMPANY, LTD.

Inventor： Chisa NISHIDA

IPC: A61K9/20 ,  A61K31/47 ,  A61K9/00

CPC classification number: A61K9/2054 ,  A61K9/0056 ,  A61K9/2027 ,  A61K31/47

Abstract: The present invention provides a pharmaceutical product which includes a solid preparation comprising pitavastatin or a salt thereof, in which production of a lactone form thereof is suppressed.The pharmaceutical product is characterized by including a solid preparation comprising the following ingredients (A) and (B): (A) pitavastatin or a salt thereof; and (B) at least one member selected from the group consisting of carmellose and a salt thereof, crospovidone, and microcrystalline cellulose, and the solid preparation having a water content of 2.9 mass % or less, wherein the solid preparation is stored in a tight package.

公开(公告)号：US20220000786A1

公开(公告)日：2022-01-06

申请号：US17418091

申请日：2019-12-27

Applicant: KOWA COMPANY, LTD.

Inventor： Chisa NISHIDA

IPC: A61K9/20 ,  A61K9/16 ,  A61K31/423

Abstract: Provided is a technique for suppressing the composition changes between pemafibrate, a salt thereof or a solvate thereof and (meth)acrylic acid-based polymers. A pharmaceutical preparation is provided by storing a pharmaceutical composition containing the following components (A) and (B) in a tight package: (A) pemafibrate, a salt thereof or a solvate thereof; and (B) a (meth)acrylic acid-based polymer.

公开(公告)号：US20220054458A1

公开(公告)日：2022-02-24

申请号：US17418129

申请日：2019-12-27

Applicant: KOWA COMPANY, LTD.

Inventor： Chisa NISHIDA

IPC: A61K31/423 ,  A61K47/38

Abstract: Provided is a technique for suppressing the composition changes between pemafibrate, a salt thereof or a solvate thereof and an alkylcellulose species. A pharmaceutical preparation is provided by storing a pharmaceutical composition containing the following components (A) and (B) in a tight package: (A) pemafibrate, a salt thereof or a solvate thereof; and (B) an alkylcellulose species.

公开(公告)号：US20220096443A1

公开(公告)日：2022-03-31

申请号：US17418518

申请日：2019-12-27

Applicant: KOWA COMPANY, LTD.

Inventor： Shin SUGIMOTO ,  Akito MINAMIZONO ,  Chisa NISHIDA

IPC: A61K31/423 ,  A61K47/32 ,  A61K47/38

Abstract: Provided is a pharmaceutical composition containing pemafibrate, a salt thereof or a solvate thereof and having excellent homogeneity. The pharmaceutical composition is provided to contain the following components (A) and (B): (A) pemafibrate, a salt thereof or a solvate thereof; and (B) one or more selected from the group consisting of the following components (B-1) and (B-7): (B-1) an alkylcellulose and a salt thereof; and a (meth)acrylic acid-based polymer.